Search Results - "Meechan, D W"

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  1. 1

    Cognitive ability is associated with altered medial frontal cortical circuits in the LgDel mouse model of 22q11.2DS by Meechan, D W, Rutz, H L H, Fralish, M S, Maynard, T M, Rothblat, L A, LaMantia, A-S

    Published in Cerebral cortex (New York, N.Y. 1991) (01-05-2015)
    “…We established a relationship between cognitive deficits and cortical circuits in the LgDel model of 22q11 Deletion Syndrome (22q11DS)-a genetic syndrome with…”
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    Journal Article
  2. 2

    Limited influence of olanzapine on adult forebrain neural precursors in vitro by Councill, J.H., Tucker, E.S., Haskell, G.T., Maynard, T.M., Meechan, D.W., Hamer, R.M., Lieberman, J.A., LaMantia, A.-S.

    Published in Neuroscience (01-01-2006)
    “…We evaluated the activity of the atypical antipsychotic drug olanzapine on differentiation and gene expression in adult neural precursor cells in vitro. Neural…”
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  3. 3

    Single nucleotide polymorphisms in the leptin receptor gene: studies in anorexia nervosa by Quinton, N D, Meechan, D W, Brown, K, Eastwood, H, Blakemore, A I F

    Published in Psychiatric genetics (01-12-2004)
    “…Anorexia nervosa is an eating disorder of unknown aetiology. There is significant evidence for a genetic component in the pathogenesis of this disorder. A…”
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  4. 4

    Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes by Meechan, D.W., Maynard, T.M., Tucker, E.S., LaMantia, A.-S.

    “…▶ 22q11DS genes are expressed embryonically at mesenychmal/epithelial induction sites. ▶ Embryonic neurogenesis and neuronal migration are altered in a model…”
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  5. 5

    Mitochondrial localization and function of a subset of 22q11 deletion syndrome candidate genes by Maynard, T.M., Meechan, D.W., Dudevoir, M.L., Gopalakrishna, D., Peters, A.Z., Heindel, C.C., Sugimoto, T.J., Wu, Y., Lieberman, J.A., LaMantia, A.-S.

    Published in Molecular and cellular neuroscience (29-10-2008)
    “…Six genes in the 1.5 Mb region of chromosome 22 deleted in DiGeorge/22q11 deletion syndrome– Mrpl40, Prodh, Slc25a1, Txnrd2, T10, and Zdhhc8–encode…”
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  6. 6

    Specific mesenchymal/epithelial induction of olfactory receptor, vomeronasal, and gonadotropin‐releasing hormone (GnRH) neurons by Rawson, N.E., Lischka, F. W., Yee, K.K., Peters, A.Z., Tucker, E.S., Meechan, D.W., Zirlinger, M., Maynard, T.M., Burd, G.B., Dulac, C., Pevny, L., LaMantia, A.‐S.

    Published in Developmental dynamics (01-06-2010)
    “…We asked whether specific mesenchymal/epithelial (M/E) induction generates olfactory receptor neurons (ORNs), vomeronasal neurons (VRNs), and…”
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  7. 7

    Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome by Meechan, D.W., Maynard, T.M., Wu, Y., Gopalakrishna, D., Lieberman, J.A., LaMantia, A.-S.

    Published in Molecular and cellular neuroscience (15-12-2006)
    “…We evaluated the consequences of heterozygous chromosome 22q11 deletion – a significant genetic risk for schizophrenia – for expression levels and patterns of…”
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  8. 8

    When Half Is Not Enough: Gene Expression and Dosage in the 22q11 Deletion Syndrome by MEECHAN, D. W., MAYNARD, T. M., GOPALAKRISHNA, D., WU, Y., LAMANTIA, AND A.-S.

    Published in Gene expression (01-01-2007)
    “…The 22q11 Deletion Syndrome (22q11DS, also known as DiGeorge or Velo-Cardio-Facial Syndrome) has a variable constellation of phenotypes including…”
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  9. 9

    Cortical interneurons require Jnk1 to enter and navigate the developing cerebral cortex by Myers, Abigail K, Meechan, Daniel W, Adney, Danielle R, Tucker, Eric S

    Published in The Journal of neuroscience (04-06-2014)
    “…Proper assembly of cortical circuitry relies on the correct migration of cortical interneurons from their place of birth in the ganglionic eminences to their…”
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  10. 10

    22q11 Gene dosage establishes an adaptive range for sonic hedgehog and retinoic acid signaling during early development by Maynard, Thomas M, Gopalakrishna, Deepak, Meechan, Daniel W, Paronett, Elizabeth M, Newbern, Jason M, LaMantia, Anthony-Samuel

    Published in Human molecular genetics (15-01-2013)
    “…We asked whether key morphogenetic signaling pathways interact with 22q11 gene dosage to modulate the severity of cranial or cardiac anomalies in DiGeorge/22q1…”
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  11. 11

    Mitochondral localization and function of a subset of 22q11 Deletion Syndrome candidate genes by Maynard, T. M., Meechan, D. W., Dudevoir, M. L., Gopalakrishna, D., Peters, A. Z., Heindel, C. C., Sugimoto, T. J., Wu, Y., Lieberman, J. A., LaMantia, A.-S.

    Published in Molecular and cellular neuroscience (15-08-2008)
    “…Six genes in the 1.5 MB region of chromosome 22 deleted in DiGeorge/22q11 Deletion Syndrome— Mrpl40, Prodh, Slc25a1, Txnrd2, T10 , and Zdhhc8 —encode…”
    Get full text
    Journal Article