Search Results - "Mee, A. P."

Herpes simplex virus type 1 DNA is located within Alzheimer's disease amyloid plaques by Wozniak, MA, Mee, AP, Itzhaki, RF

“…The brains of Alzheimer's disease sufferers are characterized by amyloid plaques and neurofibrillary tangles. However, the cause(s) of these features and those…”
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Paramyxoviruses and Paget’s disease: the affirmative view by Mee, A.P

“…Evidence has accumulated over the past 20 years to implicate paramyxoviruses in the etiopathology of Paget's disease. In the USA, the predominant virus…”
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Novel Mutations in the 1α‐Hydroxylase (P450c1) Gene in Three Families with Pseudovitamin D–Deficiency Rickets Resulting in Loss of Functional Enzyme Activity in Blood‐Derived Macrophages by Smith, S. J., Rucka, A. K., Berry, J. L., Davies, M., Mylchreest, S., Paterson, C. R., Heath, D. A., Tassabehji, M., Read, A. P., Mee, A. P., Mawer, E. B.

“…Pseudovitamin D–defiency rickets (PDDR) is an autosomal recessive disorder characterized by hypocalcemia, rickets (which are resistant to treatment with…”
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Hypercalcaemia in two dogs caused by excessive dietary supplementation of vitamin D by Mellanby, R.J, Mee, A.P, Berry, J.L, Herrtage, M.E

“…A three‐year‐old Border collie was presented with a two‐week history of lethargy, stiff gait, polydipsia and polyuria. Biochemical analysis revealed…”
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Demonstration of estrogen receptor mRNA in bone using in situ reverse-transcriptase polymerase chain reaction by Hoyland, J.A., Mee, A.P., Baird, P., Braidman, I.P., Mawer, E.B., Freemont, A.J.

“…Falling estrogen levels affect the female skeleton profoundly. Following menopause, estrogen lack is a major cause of osteoporosis. The site of estrogen action…”
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Hypocalcaemia associated with low serum vitamin D metabolite concentrations in two dogs with protein-losing enteropathies by Mellanby, R.J, Mellor, P.J, Roulois, A, Baines, E.A, Mee, A.P, Berry, J.L, Herrtage, M.E

“…Protein‐losing enteropathies were diagnosed in two dogs that were initially presented with diarrhoea and weight loss. Plasma biochemistry in both cases…”
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Detection of canine distemper virus in 100% of Paget’s disease samples by in situ-reverse transcriptase-polymerase chain reaction by Mee, A.P., Dixon, J.A., Hoyland, J.A., Davies, M., Selby, P.L., Mawer, E.B.

“…Previous evidence implicating paramyxoviruses in the aetiopathology of Paget’s disease of bone has been controversial. While several groups have demonstrated…”
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Hypercalcaemia associated with granulomatous lymphadenitis and elevated 1,25 dihydroxyvitamin D concentration in a dog by Mellanby, R.J, Mellor, P, Villiers, E.J, Herrtage, M.E, Halsall, D, O'Rahilly, S, McNeil, P.E, Mee, A.P, Berry, J.L

“…A seven‐year‐old Labrador was presented with weight loss and mild generalised lymphadenopathy. Histopathology of an excised lymph node by the referring…”
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Generation of multinucleated osteoclast-like cells from canine bone marrow : effects of canine distemper virus by MEE, A. P, MAY, C, BENNETT, D, SHARPE, P. T

“…Recent evidence has implicated canine distemper virus (CDV) as a possible aetiologic agent in Paget's disease of bone and the canine bone disorder, metaphyseal…”
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Demonstration of vitamin D receptor transcripts in actively resorbing osteoclasts in bone sections by MEE, A. P, HOYLAND, J. A, BRAIDMAN, I. P, FREEMONT, A. J, DAVIES, M, MAWER, E. B

“…The effects of the active metabolite of vitamin D, 1,25 dihydroxyvitamin D3 (1,25D), are mediated via the vitamin D receptor (VDR). 1,25D is known to have…”
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Canine distemper virus transcripts detected in the bone cells of dogs with metaphyseal osteopathy by Mee, A P, Gordon, M T, May, C, Bennett, D, Anderson, D C, Sharpe, P T

“…Using the technique of in situ hybridisation, we have recently extended our observations that canine distemper virus (CDV) is present in the bone cells of…”
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Canine bone marrow cell cultures infected with canine distemper virus : an in vitro model of Paget's disease by MEE, A. P, HOYLAND, J. A, BAIRD, P, BENNETT, D, SHARPE, P. T

“…We have previously shown that the canine paramyxovirus, canine distemper virus (CDV), is a possible aetiologic agent in Paget's disease of bone and in the…”
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Novel and sensitive detection systems for the vitamin D receptor--in situ-reverse transcriptase-polymerase chain reaction and immunogold cytochemistry by Mee, A P, Davenport, L K, Hoyland, J A, Davies, M, Mawer, E B

“…The receptor for the active metabolite of vitamin D, 1,25(OH)(2)D(3), known as the vitamin D receptor (VDR), belongs to the steroid hormone nuclear receptor…”
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QUANTIFICATION OF VITAMIN D RECEPTOR mRNA IN TISSUE SECTIONS DEMONSTRATES THE RELATIVE LIMITATIONS OF IN SITU‐REVERSE TRANSCRIPTASE‐POLYMERASE CHAIN REACTION by MEE, ANDREW P., DENTON, JOHN, HOYLAND, JUDITH A., DAVIES, MICHAEL, MAWER, E. BARBARA

“…In situ‐reverse transcriptase‐polymerase chain reaction (IS‐RT‐PCR) is a recently described technique that is used to localize low levels of mRNA within cells…”
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Paramyxoviruses in Paget's disease by Gordon, M T, Mee, A P, Sharpe, P T

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Cyclic hydrostatic pressure and particles increase synthesis of 1,25-dihydroxyvitamin D3 by human macrophages in vitro by Evans, C E, Mylchreest, S, Mee, A P, Berry, J L, Andrew, J G

“…1,25-Dihydroxyvitamin D(3) has a pivotal role in bone resorption and osteoclast activity. As activated macrophages are known to synthesise…”
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Functional, molecular, and biochemical characterization of streptozotocin-induced diabetes by WARD, Donald T, KAM YAU, S, MEE, Andrew P, MAWER, E. Barbara, MILLER, Christopher A, GARLAND, Hugh O, RICCARDI, Daniela

“…Altered divalent cation homeostasis with bone mineral loss, hypercalciuria, and hypomagnesemia have been associated consistently with human diabetes mellitus…”
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Prevalence of canine distemper antibodies in the pagetic population by Gordon, M T, Bell, S C, Mee, A P, Mercer, S, Carter, S D, Sharpe, P T

“…Recent molecular evidence has implicated canine distemper virus (CDV) as a possible aetiologic agent in Paget's disease. However, previous serological studies…”
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Detection of canine distemper virus in bone cells in the metaphyses of distemper‐infected dogs by Mee, Andrew P., Webber, David M., May, Christopher, Bennett, David, Sharpe, Paul T., Anderson, David C.

“…In the light of recent evidence implicating canine distemper virus (CDV) as a possible etiologic agent in Paget's disease of bone, we thought that it would be…”
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A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Paget's disease by Hoyland, Judith A, Dixon, Janet A, Berry, Jacqueline L, Davies, Michael, Selby, Peter L, Mee, Andrew P

“…Previous evidence implicating Paramyxoviruses in the aetiopathology of Paget's disease of bone has proved controversial. Whilst several groups have…”
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