Search Results - "Medvedeva, Svetlana M"

Synthesis of 4,5-Dihydro-1H-[1,2]dithiolo[3,4-c]quinoline-1-thione Derivatives and Their Application as Protein Kinase Inhibitors by Medvedeva, Svetlana M., Shikhaliev, Khidmet S.

“…This study represents the design and synthesis of a new set of hybrid and chimeric derivatives of…”
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New Hybrid Tetrahydropyrrolo[3,2,1- ij ]quinolin-1-ylidene-2-thioxothiazolidin-4-ones as New Inhibitors of Factor Xa and Factor XIa: Design, Synthesis, and In Silico and Experimental Evaluation by Novichikhina, Nadezhda P, Shestakov, Alexander S, Medvedeva, Svetlana M, Lagutina, Anna M, Krysin, Mikhail Yu, Podoplelova, Nadezhda A, Panteleev, Mikhail A, Ilin, Ivan S, Sulimov, Alexey V, Tashchilova, Anna S, Sulimov, Vladimir B, Geronikaki, Athina, Shikhaliev, Khidmet S

“…Despite extensive research in the field of thrombotic diseases, the prevention of blood clots remains an important area of study. Therefore, the development of…”
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6-Hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline Demonstrates Anti-Inflammatory Properties and Reduces Oxidative Stress in Acetaminophen-Induced Liver Injury in Rats by Kryl'skii, Evgenii D, Kravtsova, Svetlana E, Popova, Tatyana N, Matasova, Larisa V, Shikhaliev, Khidmet S, Medvedeva, Svetlana M

“…We examined the effects of 6-hydroxy-2,2,4-trimethyl-1,2-dihydroquinoline on markers of liver injury, oxidative status, and the extent of inflammatory and…”
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6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Alleviates Oxidative Stress and NF-κB-Mediated Inflammation in Rats with Experimental Parkinson’s Disease by Kryl’skii, Evgenii D., Razuvaev, Grigorii A., Popova, Tatyana N., Medvedeva, Svetlana M., Shikhaliev, Khidmet S.

“…A study was conducted to investigate the effects of different doses of 6-hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline (HTHQ) on motor coordination…”
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6-Hydroxy-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline Demonstrates Neuroprotective Properties in Experimental Parkinson's Disease by Enhancing the Antioxidant System, Normalising Chaperone Activity and Suppressing Apoptosis by Kryl’skii, Evgenii D., Razuvaev, Grigorii A., Popova, Tatyana N., Oleinik, Sergei A., Medvedeva, Svetlana M., Shikhaliev, Khidmet S.

“…Parkinson's disease (PD) is a neurodegenerative disease, whereby disturbances within the antioxidant defence system, increased aggregation of proteins, and…”
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Appendix A. dithioloquinolinethiones as new potential multitargeted antibacterial and antifungal agents: Synthesis, biological evaluation and molecular docking studies by Kartsev, V., Shikhaliev, Khidmet S., Geronikaki, A., Medvedeva, Svetlana M., Ledenyova, Irina V., Krysin, Mikhail Yu, Petrou, A., Ciric, A., Glamoclija, J., Sokovic, M.

“…Herein we report the design, synthesis, molecular docking study and evaluation of antimicrobial activity of ten new dithioloquinolinethiones. The structures of…”
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Application of Molecular Modeling to Development of New Factor Xa Inhibitors by Sinauridze, Elena I., Ataullakhanov, Fazoil I., Krysin, Michael Yu, Shikhaliev, Khidmet S., Kutov, Danil C., Sulimov, A. V., Katkova, E. V., Kochugaeva, Maria P., Gribkova, Irina V., Sulimov, V. B., Medvedeva, Svetlana M.

“…In consequence of the key role of factor Xa in the clotting cascade and absence of its activity in the processes that do not affect coagulation, this protein…”
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Efficient synthesis of substituted 8-(pyrazolo[3,4-d]pyrimidin-6-yl)-1,2-dihydroquinolines by Medvedeva, Svetlana M., Kosheleva, Yevgeniya A., Berdnikova, Mariya A., Shikhaliev, Khidmet S.

“…An effective method for the synthesis of 8-(1-aryl-4-methoxy-1 Н -pyrazolo[3,4- d ]pyrimidin-6-yl)-2,2,4-trimethyl-1,2-dihydroquinolines was developed on the…”
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(3+2) Cycloaddition reactions in the synthesis of C(4)–N(5)-condensed tetrahydropyrrolo[3,4-c]pyrrole-1,3-diones (microreview) by Medvedeva, Svetlana M., Shikhaliev, Khidmet S.

“…This microreview summarizes the approaches to constructing tricyclic tetrahydropyrrolo[3,4- c ]pyrrole-1,3-diones condensed at the C(4)–N(5)bond with five-,…”
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Reaction of substituted 1-methylthio-4,5-dihydro[1,2]dithiolo[3,4-c]quinolin iodides with arylamines. Synthesis of novel 1,2-dithiolo[3,4-c]quinolin-1-ylidene(aryl)amines and 10-(arylimino)-7,10-dihydro[1,2]dithiolo[3,4-c]pyrrolo[3,2,1-ij]quinoline-4,5-diones by Medvedeva, Svetlana M., Zubkov, Fedor I., Yankina, Kristina Yu, Grudinin, Dmitry G., Shikhaliev, Khidmet S.

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New multicomponent method for the synthesis of polyhydrogenated pyrazino[1,2-a]quinolines by Medvedeva, Svetlana M., Shikhlaliev, Khidmet S., Krysin, Mikhail Yu, Gotsak, Irina V.

“…A new one-pot method for the synthesis of 2,3,4,6,7,8,9,10-octahydro-1 H -pyrazino[1,2- a ]quinolines was developed based on a three-component reaction between…”
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Synthesis of substituted pyrazolo[3,4-d]pyrimidines by reactions of 5-amino-1-phenyl-1H-pyrazole derivatives with N-substituted isatins by Kosheleva, Yevgeniya A., Medvedeva, Svetlana M., Shikhaliev, Khidmet S., Zubkov, Fedor I., Ryzhkova, Elena A., Prezent, Mikhail A.

“…The reaction of N- substituted isatins with 5-amino-1-phenyl-1 H -pyrazole-4-carboxamide in refluxing methanol in the presence of excess sodium methoxide led…”
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Synthesis of 4,5-Dihydro-1H-1,2dithiolo3,4-cquinoline-1-thione Derivatives and Their Application as Protein Kinase Inhibitors by Medvedeva, Svetlana M, Shikhaliev, Khidmet S

“…This study represents the design and synthesis of a new set of hybrid and chimeric derivatives of…”
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Synthesis of 4,5-Dihydro-1 H -[1,2]dithiolo[3,4- c ]quinoline-1-thione Derivatives and Their Application as Protein Kinase Inhibitors by Medvedeva, Svetlana M, Shikhaliev, Khidmet S

“…This study represents the design and synthesis of a new set of hybrid and chimeric derivatives of…”
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Preparation of individual derivatives in 1,3-oxazino[5,4,3-ij]quinolines and 1,4-oxazino[2,3,4-ij]quinolines series by column chromatography and their mass spectrometric study by Medvedeva, Svetlana M., Movchan, Alexey V., Bondarenko, Ksenia A., Shikhalieva, Ksenia Dz, Shikhaliev, Khidmet S.

“…Hundreds of highly effective compounds that have a complex of practically useful properties are known among tricyclic hydroquinolines. Therefore, the…”
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History and Morality: 21 Shishkin Readings by Svetlana M. Medvedeva

“…23d December 2016 the Department of Philosophy of MGIMO-University conducted annual XXI Shishkin Readings in memory of famous Russian philosopher A. F…”
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History and Morality: 21 Shishkin Readings by Svetlana M. Medvedeva

“…23d December 2016 the Department of Philosophy of MGIMO-University conducted annual XXI Shishkin Readings in memory of famous Russian philosopher A. F…”
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Self-Sacrifice of a Scientist in Soviet-Russian Cinema by Svetlana M. Medvedeva

“…In the article we analyze the evolution of the idea of self-sacrifice of a scientist in Soviet-Russian cinema (from 1930th until now). The research is based on…”
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Investigation of catalytic properties of glutathione reductase obtained by chromatographic methods from the liver of rats with paracetamol-induced liver damage upon administration of 6-hydroxy-2,2,2,4-trimethyl-1,2-dihydroquinoline by Kravtsova, Svetlana E., Popova, Tatyana N., Kryl’skii, Evgenii D., Agarkov, Alexander A., Shikhaliev, Khidmet S., Medvedeva, Svetlana M., Oleinik, Sergey A., Lavruschev, Andrei I.

“…The aim of the present study was to analyze some catalytic and regulatory properties of the enzyme preparation of glutathione reductase (GR, EC 1.6.4.2.)…”
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Synthesis of substituted 1,3-oxazino[5,4,3-ij]quinolin-1,3-diones by the oxidation of various pyrrolo[3,2,1-ij]quinoline-1,2-diones with m-chloroperbenzoic acid by Medvedeva, Svetlana M., Movchan, Alexey V., Sidorenko, Oleg E., Shestakov, Alexander S., Ledenyova, Irina V., Zavarzin, Igor V., Shikhaliev, Khidmet S.

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