Search Results - "Medve, Robert A."

Randomized, Double-Blind, Placebo-Controlled Study of the Abuse Potential of Different Formulations of Oral Oxycodone by Webster, Lynn R., Bath, Brad, Medve, Robert A., Marmon, Tonya, Stoddard, Gregory J.

“…Objective.  The objective of this study was to evaluate the pharmacokinetics and abuse potential of different formulations of oxycodone. Design.  The…”
Get full text

Oral tramadol for the treatment of pain of 7-30 days' duration in children by ROSE, John B, FINKEL, Julia C, ARQUEDAS-MOHS, Adriano, HIMELSTEIN, Bruce P, SCHREINER, Mark, MEDVE, Robert A

“…This open-label, multicenter trial was designed to determine the safety profile and analgesic efficacy of tramadol for the treatment of painful conditions…”
Get full text

Opioid formulations in development designed to curtail abuse: who is the target? by Webster, Lynn R, Bath, Brad, Medve, Robert A

“…Opioids are increasingly prescribed for chronic cancer and noncancer pain, and misuse, abuse, and diversion have risen dramatically. Formulations are being…”
Get more information

Safety, tolerability, pharmacokinetics, and pharmacodynamic effects of naloxegol at peripheral and central nervous system receptors in healthy male subjects: A single ascending-dose study by Eldon, Michael A., Kugler, Alan R., Medve, Robert A., Bui, Khanh, Butler, Kathleen, Sostek, Mark

“…This randomized, double‐blind, placebo‐controlled, ascending‐dose, crossover study evaluated single oral doses of naloxegol (NKTR‐118; 8, 15, 30, 60, 125, 250,…”
Get full text

Safety, tolerability, and pharmacokinetics of multiple ascending doses of naloxegol by Eldon, Michael A., Kugler, Alan R., Medve, Robert A., Bui, Khanh, Butler, Kathleen, Sostek, Mark

“…Opioid‐induced constipation (OIC) is the most common and often a treatment‐limiting adverse event (AE) of opioid therapy for chronic pain. Naloxegol…”
Get full text

An evaluation of the efficacy and tolerability of oral tramadol hydrochloride tablets for the treatment of postsurgical pain in children by FINKEL, Julia C, ROSE, John B, SCHMITZ, Michael L, BIRMINGHAM, Patrick K, ULMA, George A, GUNTER, Joel B, CNAAN, Avital, COTE, Charles J, MEDVE, Robert A, SCHREINER, Mark S

“…In this double-blinded, randomized, multicenter study, we examined analgesic efficacy and tolerability of tramadol in postoperative pediatric patients…”
Get full text

An Evaluation of the Efficacy and Tolerability of Oral Tramadol Hydrochloride Tablets for the Treatment of Postsurgical Pain in Children by Finkel, Julia C., Rose, John B., Schmitz, Michael L., Birmingham, Patrick K., Ulma, George A., Gunter, Joel B., Cnaan, Avital, Coté, Charles J., Medve, Robert A., Schreiner, Mark S.

“…In this double-blinded, randomized, multicenter study, we examined analgesic efficacy and tolerability of tramadol in postoperative pediatric patients…”
Get full text

Oral Tramadol for the Treatment of Pain of 7–30 Days’ Duration in Children by Rose, John B., Finkel, Julia C., Arquedas-Mohs, Adriano, Himelstein, Bruce P., Schreiner, Mark, Medve, Robert A.

Get full text