Search Results - "Medina Rivero, Emilio"
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Immunomodulatory Effects Mediated by Dopamine
Published in Journal of immunology research (01-01-2016)“…Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory functions at the systemic level. The peripheral and central nervous…”
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Determination of Peptide Profile Consistency and Safety of Collagen Hydrolysates as Quality Attributes
Published in Journal of food science (01-03-2019)“…Collagen hydrolysates are dietary supplements used for nutritional and medical purposes. They are complex mixtures of low‐molecular‐weight peptides obtained…”
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Analysis of recombinant monoclonal antibodies by capillary zone electrophoresis
Published in Electrophoresis (01-04-2013)“…Analytical platforms that characterize charge heterogeneity in therapeutic proteins, such as mAbs, are important tools that can be used to define quality…”
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Assessment of Physicochemical Properties of Rituximab Related to Its Immunomodulatory Activity
Published in Journal of immunology research (01-01-2015)“…Rituximab is a chimeric monoclonal antibody employed for the treatment of CD20-positive B-cell non-Hodgkin’s lymphoma, chronic lymphocytic leukemia, rheumatoid…”
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Validation of three viable-cell counting methods: Manual, semi-automated, and automated
Published in Biotechnology reports (Amsterdam, Netherlands) (01-09-2015)“…[Display omitted] A viable cell count is essential to evaluate the kinetics of cell growth. Since the hemocytometer was first used for counting blood cells,…”
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Sequencing Analysis and Identification of the Primary Peptide Component of the Dialyzable Leukocyte Extract "Transferon Oral": The Starting Point to Understand Its Mechanism of Action
Published in Frontiers in pharmacology (07-10-2020)“…"Transferon Oral" is a peptide-derived product with immunomodulatory properties obtained from the lysis and dialysis of human buffy coat. Its active…”
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Validation of a Cell Proliferation Assay to Assess the Potency of a Dialyzable Leukocyte Extract Intended for Batch Release
Published in Molecules (Basel, Switzerland) (20-09-2019)“…Transferon is a blood product with immunomodulatory properties constituted by a complex mixture of peptides obtained from a human dialyzable leukocyte extract…”
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Efficient enzymatic hydrolysis for enriching the antioxidant content of agro‐food industrial residues
Published in JSFA reports (01-09-2023)Get full text
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CD80 Expression Correlates with IL-6 Production in THP-1-Like Macrophages Costimulated with LPS and Dialyzable Leukocyte Extract (Transferon®)
Published in Journal of immunology research (01-01-2019)“…Transferon® is a complex drug based on a mixture of low molecular weight peptides. This biotherapeutic is employed as a coadjuvant in clinical trials of…”
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Characterization of a Complex Mixture of Immunomodulator Peptides Obtained from Autologous Urine
Published in Journal of immunology research (2020)“…A complex mixture of peptides plays a key role in the regulation of the immune system; different sources as raw materials mainly from animals and vegetables…”
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Quality attributes of partially hydrolyzed collagen in a liquid formulation used for skin care
Published in Journal of cosmetic dermatology (01-01-2021)“…Background The deterioration of the skin accentuates over time, affecting its aesthetic appearance. This is characterized by the weakening of the mechanisms…”
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Analysis of therapeutic proteins and peptides using multiangle light scattering coupled to ultra high performance liquid chromatography
Published in Journal of separation science (01-05-2015)“…Analysis of the physical properties of biotherapeutic proteins is crucial throughout all the stages of their lifecycle. Herein, we used size‐exclusion ultra…”
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Development of Functional Antibodies Directed to Human Dialyzable Leukocyte Extract (Transferon®)
Published in Journal of immunology research (01-01-2019)“…Transferon® is an immunomodulator made of a complex mixture of peptides from human dialyzable leucocyte extracts (hDLEs). Development of surrogate antibodies…”
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14
Taking advantage of a high-throughput flow cytometer for the implementation of an ADCC assay for regulatory compliance
Published in Biotechnology reports (Amsterdam, Netherlands) (01-06-2020)“…•High-throughput flow cytometry for the evaluation of ADCC potency.•Optimization of biological assays for batch release testing of biopharmaceuticals.•Quickly…”
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Physicochemical and Biological Characterization of a Biosimilar Trastuzumab
Published in BioMed research international (01-01-2015)“…According to the World Health Organization, the incidence of malignant neoplasms and endocrine, blood, and immune disorders will increase in the upcoming…”
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Characterization and comparability of biosimilars: A filgrastim case of study and regulatory perspectives for Latin America
Published in Electronic Journal of Biotechnology (01-11-2016)“…Developing countries have an estimate of ten times more approved biosimilars than developed countries. This disparity demands the need of an objective…”
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Herpes Murine Model as a Biological Assay to Test Dialyzable Leukocyte Extracts Activity
Published in Journal of immunology research (01-01-2015)“…Human dialyzable leukocyte extracts (DLEs) are heterogeneous mixtures of low-molecular-weight peptides that are released on disruption of peripheral blood…”
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New Alternatives for Autoimmune Disease Treatments: Physicochemical and Clinical Comparability of Biosimilar Etanercept
Published in Journal of immunology research (01-01-2016)“…Etanercept is a recombinant fusion protein approved for the treatment of TNF-α mediated diseases such as rheumatoid arthritis (RA), psoriasis, psoriatic…”
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Response to: Comment on “New Alternatives for Autoimmune Disease Treatments: Physicochemical and Clinical Comparability of Biosimilar Etanercept”
Published in Journal of immunology research (01-01-2018)“…This communication responds to the Letter to the Editor [1], where noticeably Messrs. Brian Hassett, Steven Vicik, and Brian Fitzpatrick from Pfizer Biotech…”
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Swine Dialyzable Spleen Extract as Antiviral Prophylaxis
Published in Journal of medicinal food (01-11-2015)“…Worldwide, the most highly consumed meat is of porcine origin. The production and distribution of swine meat are affected by diverse health matters, such as…”
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