Search Results - "Medina, Pablo José"

The phospholipase A2 activity of peroxiredoxin 6 modulates NADPH oxidase 2 activation via lysophosphatidic acid receptor signaling in the pulmonary endothelium and alveolar macrophages by Vázquez‐Medina, José Pablo, Dodia, Chandra, Weng, Liwei, Mesaros, Clementina, Blair, Ian A., Feinstein, Sheldon I., Chatterjee, Shampa, Fisher, Aron B.

“…ABSTRACT Peroxiredoxin 6 (Prdx6) is essential for activation of NADPH oxidase type 2 (NOX2) in pulmonary microvascular endothelial cells (PMVECs), alveolar…”
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Natural Tolerance to Ischemia and Hypoxemia in Diving Mammals: A Review by Allen, Kaitlin N., Vázquez-Medina, José Pablo

“…Reperfusion injury follows ischemia/reperfusion events occurring during myocardial infarction, stroke, embolism, and other peripheral vascular diseases…”
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Short-term elevations in glucocorticoids do not alter telomere lengths: A systematic review and meta-analysis of non-primate vertebrate studies by Zane, Lauren, Ensminger, David C, Vázquez-Medina, José Pablo

“…Background The neuroendocrine stress response allows vertebrates to cope with stressors via the activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis,…”
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The Role of Peroxiredoxin 6 in Cell Signaling by Arevalo, José A, Vázquez-Medina, José Pablo

“…Peroxiredoxin 6 (Prdx6, 1-cys peroxiredoxin) is a unique member of the peroxiredoxin family that, in contrast to other mammalian peroxiredoxins, lacks a…”
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Hypoxia exposure blunts angiogenic signaling and upregulates the antioxidant system in endothelial cells derived from elephant seals by Allen, Kaitlin N, Torres-Velarde, Julia María, Vazquez, Juan Manuel, Moreno-Santillán, Diana D, Sudmant, Peter H, Vázquez-Medina, José Pablo

“…Elephant seals exhibit extreme hypoxemic tolerance derived from repetitive hypoxia/reoxygenation episodes they experience during diving bouts. Real-time…”
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Impact of the COVID-19 pandemic and restrictive measures on acute appendicitis: Do not let your guard down by Herrera, Jeronimo, Arrechea, Ramiro, Mihura, Matías, Bregante, Mariano, Medina, José, Pirchi, Daniel

“…Background: The COVID-19 pandemic has altered the usual dynamics of consultation and presentation for acute appendicitis (AA). The aim of this study was to…”
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Potentiation of Acetylcholine-Induced Relaxation of Aorta in Male UC Davis Type 2 Diabetes Mellitus (UCD-T2DM) Rats: Sex-Specific Responses by Akther, Farjana, Razan, Md Rahatullah, Shaligram, Sonali, Graham, James L, Stanhope, Kimber L, Allen, Kaitlin N, Vázquez-Medina, José Pablo, Havel, Peter J, Rahimian, Roshanak

“…Previous reports suggest that diabetes may differentially affect the vascular beds of females and males. The objectives of this study were to examine whether…”
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Plasma FGF21 concentrations, adipose fibroblast growth factor receptor-1 and β-klotho expression decrease with fasting in northern elephant seals by Suzuki, Miwa, Lee, Andrew Y, Vázquez-Medina, José Pablo, Viscarra, Jose A, Crocker, Daniel E, Ortiz, Rudy M

“…Highlights • We tested effects of fast on FGF21-associated changes in elephant seal. • Expression of FGF receptor-1 and its co-activator in adipose was…”
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In silico Characterization of the Heme Oxygenase 1 From Bottlenose Dolphin ( Tursiops truncatus ): Evidence of Changes in the Active Site and Purifying Selection by Reyes-Ramos, Carlos A, Gaxiola-Robles, Ramón, Vázquez-Medina, José Pablo, Ramírez-Jirano, Luis Javier, Bitzer-Quintero, Oscar Kurt, Zenteno-Savín, Tania

“…Cetacea is a clade well-adapted to the aquatic lifestyle, with diverse adaptations and physiological responses, as well as a robust antioxidant defense system…”
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Apnea stimulates the adaptive response to oxidative stress in elephant seal pups by Vázquez-Medina, José Pablo, Zenteno-Savín, Tania, Tift, Michael S, Forman, Henry Jay, Crocker, Daniel E, Ortiz, Rudy M

“…Extended breath-hold (apnea) bouts are routine during diving and sleeping in seals. These apneas result in oxygen store depletion and blood flow redistribution…”
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Prolonged fasting increases glutathione biosynthesis in postweaned northern elephant seals by Vázquez-Medina, José Pablo, Zenteno-Savín, Tania, Forman, Henry Jay, Crocker, Daniel E, Ortiz, Rudy M

“…Northern elephant seals experience prolonged periods of absolute food and water deprivation (fasting) while breeding, molting or weaning. The postweaning fast…”
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Rapid Hypoxia‐Induced Upregulation of Glutathione‐Related Genes May Protect Elephant Seal Endothelial Cells Against Oxidative Stress by Allen, Kaitlin, Li, Alexander, Vázquez‐Medina, José Pablo

“…Northern elephant seals (Mirounga angustirostris) experience extreme fluctuations in blood oxygen levels during repeated bouts of deep diving. Such…”
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Fasting ameliorates oxidative stress: A review of physiological strategies across life history events in wild vertebrates by Ensminger, David C., Salvador-Pascual, Andrea, Arango, B. Gabriela, Allen, Kaitlin N., Vázquez-Medina, José Pablo

“…Fasting is a component of many species' life history due to environmental factors or behavioral patterns that limit access to food. Despite metabolic and…”
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Oxidative stress induced by phthalates in mammals: State of the art and potential biomarkers by Brassea-Pérez, Elizabeth, Hernández-Camacho, Claudia J., Labrada-Martagón, Vanessa, Vázquez-Medina, José Pablo, Gaxiola-Robles, Ramón, Zenteno-Savín, Tania

“…Phthalates, plasticizers that are widely used in consumer products including toys, cosmetics, and food containers, have negative effects in liver, kidney,…”
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Glutathione protection against dive-associated ischemia/reperfusion in ringed seal tissues by Vázquez-Medina, José Pablo, Zenteno-Savín, Tania, Elsner, Robert

“…Ischemia/reperfusion is a potentially hazardous condition that increases reactive oxygen species (ROS) production and oxidative damage. Seals of the phocid…”
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Dolphin leukocytes exhibit an attenuated cytokine response and increase heme oxygenase activity upon exposure to lipopolysaccharides by Reyes-Ramos, Carlos A., Ramírez-Jirano, Luis Javier, Bitzer-Quintero, Oscar Kurt, Vázquez-Medina, José Pablo, Gaxiola-Robles, Ramón, Zenteno-Savín, Tania

“…Cetaceans exhibit physiological adaptations that allowed the transition to aquatic life, including a robust antioxidant defense system that prevents injury…”
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Peroxiredoxin 6 suppresses ferroptosis in lung endothelial cells by Torres-Velarde, Julia María, Allen, Kaitlin N., Salvador-Pascual, Andrea, Leija, Roberto G., Luong, Diamond, Moreno-Santillán, Diana Daniela, Ensminger, David C., Vázquez-Medina, José Pablo

“…Peroxiredoxin 6 (Prdx6) repairs peroxidized membranes by reducing oxidized phospholipids, and by replacing oxidized sn-2 fatty acyl groups through…”
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Elephant seal muscle cells adapt to sustained glucocorticoid exposure by shifting their metabolic phenotype by Torres-Velarde, Julia María, Kolora, Sree Rohit Raj, Khudyakov, Jane I, Crocker, Daniel E, Sudmant, Peter H, Vázquez-Medina, José Pablo

“…Elephant seals experience natural periods of prolonged food deprivation while breeding, molting, and undergoing postnatal development. Prolonged food…”
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Functional Studies with Primary Cells Provide a System for Genome-to-Phenome Investigations in Marine Mammals by Lam, Emily K, Allen, Kaitlin N, Torres-Velarde, Julia María, Vázquez-Medina, José Pablo

“…Marine mammals exhibit some of the most dramatic physiological adaptations in their clade and offer unparalleled insights into the mechanisms driving…”
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Repeated stimulation of the HPA axis alters white blood cell count without increasing oxidative stress or inflammatory cytokines in fasting elephant seal pups by Ensminger, David C., Crocker, Daniel E., Lam, Emily K., Allen, Kaitlin N., Vázquez-Medina, José Pablo

“…The hypothalamic–pituitary–adrenal (HPA) axis controls the release of glucocorticoids, which regulate immune and inflammatory function by modulating cytokines,…”
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