Search Results - "Medina, Benjamin D"

Mitochondrial Inhibition Augments the Efficacy of Imatinib by Resetting the Metabolic Phenotype of Gastrointestinal Stromal Tumor by Vitiello, Gerardo A, Medina, Benjamin D, Zeng, Shan, Bowler, Timothy G, Zhang, Jennifer Q, Loo, Jennifer K, Param, Nesteene J, Liu, Mengyuan, Moral, Alec J, Zhao, Julia N, Rossi, Ferdinand, Antonescu, Cristina R, Balachandran, Vinod P, Cross, Justin R, DeMatteo, Ronald P

“…Imatinib dramatically reduces gastrointestinal stromal tumor (GIST) F-FDG uptake, providing an early indicator of treatment response. Despite decreased glucose…”
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Rethinking T Cells in Pancreas Cancer by Medina, Benjamin D, Miller, George

“…Patients with pancreatic ductal adenocarcinoma do not benefit from checkpoint blockade. However, human tumors harbor evidence of adaptive immunity in clonally…”
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Differential immune profiles distinguish the mutational subtypes of gastrointestinal stromal tumor by Vitiello, Gerardo A, Bowler, Timothy G, Liu, Mengyuan, Medina, Benjamin D, Zhang, Jennifer Q, Param, Nesteene J, Loo, Jennifer K, Goldfeder, Rachel L, Chibon, Frederic, Rossi, Ferdinand, Zeng, Shan, DeMatteo, Ronald P

“…Gastrointestinal stromal tumor (GIST) is the most common human sarcoma, frequently characterized by an oncogenic mutation in the KIT or platelet-derived growth…”
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PD-1/PD-L1 Blockade Enhances T-cell Activity and Antitumor Efficacy of Imatinib in Gastrointestinal Stromal Tumors by Seifert, Adrian M, Zeng, Shan, Zhang, Jennifer Q, Kim, Teresa S, Cohen, Noah A, Beckman, Michael J, Medina, Benjamin D, Maltbaek, Joanna H, Loo, Jennifer K, Crawley, Megan H, Rossi, Ferdinand, Besmer, Peter, Antonescu, Cristina R, DeMatteo, Ronald P

“…Tyrosine kinase inhibitors are effective in gastrointestinal stromal tumors (GISTs) but often are of transient benefit as resistance commonly develops…”
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Just breathe: 12-step robotic tracheobronchoplasty by Lazzaro, Richard, Kontopidis, Ioannis, Medina, Benjamin D.

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Characterizing a learning curve for robotic-assisted bronchoscopy: Analysis of skills acquisition in a high-volume academic center by Bott, Matthew J., Toumbacaris, Nicolas, Tan, Kay See, Husta, Bryan C., Medina, Benjamin D., Adusumilli, Prasad S., Beattie, Jason A., Lee, Robert P., Park, Bernard J., Dycoco, Joseph, Jones, David R., Chawla, Mohit, Rocco, Gaetano, Kalchiem-Dekel, Or

“…Shape-sensing robotic-assisted bronchoscopy is an emerging technology for the sampling of pulmonary lesions. We seek to characterize the shape-sensing…”
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Percutaneous Dilational Tracheostomy at the Epicenter of the SARS-CoV-2 Pandemic: Impact on Critical Care Resource Utilization and Early Outcomes by Krowsoski, Leandra, Medina, Benjamin D, DiMaggio, Charles, Hong, Charles, Moore, Samantha, Straznitskas, Andrew, Rogers, Charmel, Mukherjee, Vikramjit, Uppal, Amit, Frangos, Spiros, Bukur, Marko

“…The COVID-19 pandemic overwhelmed New York City hospitals early in the pandemic. Shortages of ventilators and sedatives prompted tracheostomy earlier than…”
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Oncogenic kinase inhibition limits Batf3-dependent dendritic cell development and antitumor immunity by Medina, Benjamin D, Liu, Mengyuan, Vitiello, Gerardo A, Seifert, Adrian M, Zeng, Shan, Bowler, Timothy, Zhang, Jennifer Q, Cavnar, Michael J, Loo, Jennifer K, Param, Nesteene J, Maltbaek, Joanna H, Rossi, Ferdinand, Balachandran, Vinod, DeMatteo, Ronald P

“…Gastrointestinal stromal tumor (GIST) is driven by an activating mutation in the proto-oncogene. Using a mouse model of GIST and human specimens, we show that…”
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The V654A second-site KIT mutation increases tumor oncogenesis and STAT activation in a mouse model of gastrointestinal stromal tumor by Zhang, Jennifer Q., Bosbach, Benedikt, Loo, Jennifer K., Vitiello, Gerardo A., Zeng, Shan, Seifert, Adrian M., Medina, Benjamin D., Param, Nesteene J., Maltbaek, Joanna H., Rossi, Ferdinand, Antonescu, Cristina R., Besmer, Peter, DeMatteo, Ronald P.

“…Gastrointestinal stromal tumor (GIST) is the most common human sarcoma and arises in the gastrointestinal tract. Most GISTs are caused by activating mutations…”
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Metastasectomy for melanoma is associated with improved overall survival in responders to targeted molecular or immunotherapy by Medina, Benjamin D., Choi, Beatrix Hyemin, Rodogiannis, Kathy G., Moran, Una, Shapiro, Richard L., Pavlick, Anna, Osman, Iman, Berman, Russell S., Lee, Ann Y.

“…Background and Objectives Metastasectomy for melanoma provides durable disease control in carefully selected patients. Similarly, BRAF‐targeted and immune…”
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Wnt/β-catenin Signaling Contributes to Tumor Malignancy and Is Targetable in Gastrointestinal Stromal Tumor by Zeng, Shan, Seifert, Adrian M, Zhang, Jennifer Q, Cavnar, Michael J, Kim, Teresa S, Balachandran, Vinod P, Santamaria-Barria, Juan A, Cohen, Noah A, Beckman, Michael J, Medina, Benjamin D, Rossi, Ferdinand, Crawley, Megan H, Loo, Jennifer K, Maltbaek, Joanna H, Besmer, Peter, Antonescu, Cristina R, DeMatteo, Ronald P

“…Gastrointestinal stromal tumor (GIST) is the most common type of sarcoma and usually harbors either a or mutation. However, the molecular basis for tumor…”
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Macrophages and CD8 + T Cells Mediate the Antitumor Efficacy of Combined CD40 Ligation and Imatinib Therapy in Gastrointestinal Stromal Tumors by Zhang, Jennifer Q, Zeng, Shan, Vitiello, Gerardo A, Seifert, Adrian M, Medina, Benjamin D, Beckman, Michael J, Loo, Jennifer K, Santamaria-Barria, Juan, Maltbaek, Joanna H, Param, Nesteene J, Moral, John A, Zhao, Julia N, Balachandran, Vinod, Rossi, Ferdinand, Antonescu, Cristina R, DeMatteo, Ronald P

“…Tyrosine kinase inhibition of gastrointestinal stromal tumors (GIST) is effective but typically culminates in resistance and is rarely curative. Immunotherapy…”
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Tyrosine Kinase Inhibition Activates Intratumoral γδ T Cells in Gastrointestinal Stromal Tumor by Etherington, Mark S, Hanna, Andrew N, Medina, Benjamin D, Liu, Mengyuan, Tieniber, Andrew D, Kwak, Hyunjee V, Tardy, Katherine J, Levin, Lillian, Do, Kevin J, Rossi, Ferdinando, Zeng, Shan, DeMatteo, Ronald P

“…γδ T cells are a rare but potent subset of T cells with pleiotropic functions. They commonly reside within tumors but the response of γδ T cells to tyrosine…”
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Oncogenic KIT Modulates Type I IFN-Mediated Antitumor Immunity in GIST by Liu, Mengyuan, Etherington, Mark S, Hanna, Andrew, Medina, Benjamin D, Vitiello, Gerardo A, Bowler, Timothy G, Param, Nesteene J, Levin, Lillian, Rossi, Ferdinand, DeMatteo, Ronald P

“…Type I IFNs are implicated in tumor immunogenicity and response to systemic therapy, but their interaction with oncogene signaling is not well understood…”
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Tyrosine Kinase Inhibition Alters Intratumoral CD8+ T-cell Subtype Composition and Activity by Tieniber, Andrew D, Hanna, Andrew N, Medina, Benjamin D, Vitiello, Gerardo A, Etherington, Mark S, Liu, Mengyuan, Do, Kevin J, Rossi, Ferdinando, DeMatteo, Ronald P

“…Targeted therapy with a tyrosine kinase inhibitor (TKI) such as imatinib is effective in treating gastrointestinal stromal tumor (GIST), but it is rarely…”
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ETV4 collaborates with Wnt/β-catenin signaling to alter cell cycle activity and promote tumor aggressiveness in gastrointestinal stromal tumor by Zeng, Shan, Seifert, Adrian M, Zhang, Jennifer Q, Kim, Teresa S, Bowler, Timothy G, Cavnar, Michael J, Medina, Benjamin D, Vitiello, Gerardo A, Rossi, Ferdinand, Loo, Jennifer K, Param, Nesteene J, DeMatteo, Ronald P

“…Gastrointestinal stromal tumor (GIST) is the most common sarcoma, often resulting from a or platelet-derived growth factor receptor alpha ( ) mutation. The…”
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Metastatic Colorectal Carcinoma by Medina, Benjamin D., MD, DeMatteo, Ronald P., MD

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