Search Results - "Medin, Paul M."

Existence of a Dose-Length Effect in Spinal Nerves Receiving Single-Session Stereotactic Ablative Radiation Therapy by Hrycushko, Brian, van der Kogel, Albert J., Phillips, Lauren, Folkert, Michael, Sayre, James W., Vernino, Steven, Hassan-Rezaeian, Nima, Foster, Ryan D., Yamada, Yoshiya, Timmerman, Robert, Medin, Paul M.

“…The spinal nerves have been observed to have a similar single-session dose tolerance to that of the spinal cord in pigs. Small-animal studies have shown that…”
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Spinal Cord Tolerance in the Age of Spinal Radiosurgery: Lessons From Preclinical Studies by Medin, Paul M., Ph.D, Boike, Thomas P., M.D

“…Clinical implementation of spinal radiosurgery has increased rapidly in recent years, but little is known regarding human spinal cord tolerance to…”
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A Method for Evaluating Quality Assurance Needs in Radiation Therapy by Huq, M. Saiful, Ph.D, Fraass, Benedick A., Ph.D, Dunscombe, Peter B., Ph.D, Gibbons, John P., Ph.D, Ibbott, Geoffrey S., Ph.D, Medin, Paul M., Ph.D, Mundt, Arno, M.D, Mutic, Sassa, Ph.D, Palta, Jatinder R., Ph.D, Thomadsen, Bruce R., Ph.D, Williamson, Jeffrey F., Ph.D, Yorke, Ellen D., Ph.D

“…The increasing complexity of modern radiation therapy planning and delivery techniques challenges traditional prescriptive quality control and quality…”
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Spinal Cord Tolerance to Reirradiation With Single-Fraction Radiosurgery: A Swine Model by Medin, Paul M., Ph.D, Foster, Ryan D., Ph.D, van der Kogel, Albert J., Ph.D, Sayre, James W., Ph.D, McBride, William H., D.Sc, Solberg, Timothy D., Ph.D

“…Purpose This study was performed to determine swine spinal cord tolerance to single-fraction, partial-volume irradiation 1 year after receiving uniform…”
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Use of the BrainLAB ExacTrac X-Ray 6D System in Image-Guided Radiotherapy by Jin, Jian-Yue, Ph.D, Yin, Fang-Fang, Ph.D, Tenn, Stephen E., Ph.D, Medin, Paul M., Ph.D, Solberg, Timothy D., Ph.D

“…Abstract The ExacTrac X-Ray 6D image-guided radiotherapy (IGRT) system will be described and its performance evaluated. The system is mainly an integration of…”
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Local Hypothermia as a Radioprotector of the Rectal Wall During Prostate Stereotactic Body Radiation Therapy by Hrycushko, Brian A., PhD, Chopra, Rajiv, PhD, Sayre, James W., PhD, Richardson, James A., PhD, Folkert, Michael R., MD, PhD, Timmerman, Robert D., MD, Medin, Paul M., PhD

“…Purpose To compare the single-fraction dose-related incidence of rectal obstruction and/or bleeding in normothermic and hypothermic rectums of a rat model…”
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Quality Assurance of Immobilization and Target Localization Systems for Frameless Stereotactic Cranial and Extracranial Hypofractionated Radiotherapy by Solberg, Timothy D., Ph.D, Medin, Paul M., Ph.D, Mullins, John, B.S, Li, Sicong, D.Sc

“…The success of stereotactic radiosurgery has stimulated significant interest in the application of such an approach for the treatment of extracranial tumors…”
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Spinal cord tolerance to single-session uniform irradiation in pigs: Implications for a dose-volume effect by Medin, Paul M, Foster, Ryan D, van der Kogel, Albert J, Sayre, James W, McBride, William H, Solberg, Timothy D

“…Abstract Background and purpose This study was performed to test the hypothesis that spinal cord radiosensitivity is significantly modified by uniform versus…”
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A microscopic oxygen transport model for ultra‐high dose rate radiotherapy in vivo: The impact of physiological conditions on FLASH effect by Guo, Lixiang, Medin, Paul M., Wang, Ken Kang‐Hsin

“…Background Ultra‐high dose rate irradiation (≥40 Gy/s, FLASH) has been shown to reduce normal tissue toxicity, while maintaining tumor control compared to…”
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Effects From Nonuniform Dose Distribution in the Spinal Nerves of Pigs: Analysis of Normal Tissue Complication Probability Models by Hrycushko, Brian, Medin, Paul M.

“…Our purpose was to evaluate normal tissue complication probability (NTCP) models for their ability to describe the increase in tolerance as the length of…”
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Spinal Cord Tolerance to Single-Fraction Partial-Volume Irradiation: A Swine Model by Medin, Paul M., Ph.D, Foster, Ryan D., Ph.D, van der Kogel, Albert J., Ph.D, Sayre, James W., Ph.D, McBride, William H., D.Sc, Solberg, Timothy D., Ph.D

“…Purpose To determine the spinal cord tolerance to single-fraction, partial-volume irradiation in swine. Methods and Materials A 5-cm-long cervical segment was…”
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Low-cost 3D print–based phantom fabrication to facilitate interstitial prostate brachytherapy training program by Chiu, Tsuicheng, Xiong, Zhenyu, Parsons, David, Folkert, Michael R., Medin, Paul M., Hrycushko, Brian

“…The purpose of this study was to manufacture a realistic and inexpensive prostate phantom to support training programs for ultrasound-based interstitial…”
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Emphasis on Repair, Not Just Avoidance of Injury, Facilitates Prudent Stereotactic Ablative Radiotherapy by Kim, D.W. Nathan, Medin, Paul M., Timmerman, Robert D.

“…Stereotactic ablative radiotherapy (SAbR) is a potent, hypofractionated treatment against cancer which puts adjacent normal tissue in potential peril. Accurate…”
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Brachial Plexus Tolerance to Single-Session SABR in a Pig Model by Hrycushko, Brian, van der Kogel, Albert J., Phillips, Lauren, Chhabra, Avneesh, Folkert, Michael R., Sayre, James W., Vernino, Steven, Hassan-Rezaeian, Nima, Yamada, Yoshiya, Timmerman, Robert, Medin, Paul M.

“…The single-session dose tolerance of the spinal nerves has been observed to be similar to that of the spinal cord in pigs, counter to the perception that…”
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Targeting accuracy of an image guided gating system for stereotactic body radiotherapy by Tenn, Stephen E, Solberg, Timothy D, Medin, Paul M

“…Recently, a commercial system capable of x-ray image guided patient positioning and respiratory gated delivery has become available. Here we describe the…”
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Spinal Nerve Tolerance to Single-Session Stereotactic Ablative Radiation Therapy by Hrycushko, Brian, van der Kogel, Albert J., Phillips, Lauren, Folkert, Michael R., Sayre, James W., Vernino, Steven, Hassan-Rezaeian, Nima, Foster, Ryan D., Yamada, Yoshiya, Timmerman, Robert, Medin, Paul M.

“…This study was performed to determine the dose-related incidence of neuropathy from single-session irradiation of the C6-C8 spinal nerves using a pig model and…”
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Technical Note: System for evaluating local hypothermia as a radioprotector of the rectum in a small animal model by Hrycushko, Brian A., Bing, Chenchen, Futch, Cecil, Wodzak, Michelle, Stojadinovic, Strahinja, Medin, Paul M., Chopra, Rajiv

“…Purpose The protective effects of induced or even accidental hypothermia on the human body are widespread with several medical uses currently under active…”
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Commissioning and initial stereotactic ablative radiotherapy experience with Vero by Solberg, Timothy D., Medin, Paul M., Ramirez, Ezequiel, Ding, Chuxiong, Foster, Ryan D., Yordy, John

“…The purpose of this study is to describe the comprehensive commissioning process and initial clinical performance of the Vero linear accelerator, a new…”
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Stereotactic Body Radiation Therapy: A New Paradigm in Radiotherapy Management of Cancer by Solberg, Timothy D., PhD, Kavanagh, Brian D., MD, Medin, Paul M., PhD

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Paralysis following stereotactic spinal irradiation in pigs suggests a tolerance constraint for single-session irradiation of the spinal nerve by Medin, Paul M, Foster, Ryan D, van der Kogel, Albert J, Meyer, Jeffrey, Sayre, James W, Huang, Hao, Öz, Orhan K

“…Abstract Background and purpose Paralysis observed during a study of vertebral bone tolerance to single-session irradiation led to further study of the…”
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