Search Results - "Medelin, Manuela"
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Glucocorticoid receptors modulate dendritic spine plasticity and microglia activity in an animal model of Alzheimer's disease
Published in Neurobiology of disease (01-12-2019)“…Chronic exposure to high circulating levels of glucocorticoids (GCs) may be a key risk factor for Alzheimer's Disease (AD) development and progression. In…”
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Cytokine inflammatory threat, but not LPS one, shortens GABAergic synaptic currents in the mouse spinal cord organotypic cultures
Published in Journal of neuroinflammation (25-06-2019)“…Synaptic dysfunction, named synaptopathy, due to inflammatory status of the central nervous system (CNS) is a recognized factor potentially underlying both…”
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Graphene Oxide Flakes Tune Excitatory Neurotransmission in Vivo by Targeting Hippocampal Synapses
Published in Nano letters (08-05-2019)“…Synapses compute and transmit information to connect neural circuits and are at the basis of brain operations. Alterations in their function contribute to a…”
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Functional rewiring across spinal injuries via biomimetic nanofiber scaffolds
Published in Proceedings of the National Academy of Sciences - PNAS (13-10-2020)“…The regrowth of severed axons is fundamental to reestablish motor control after spinal-cord injury (SCI). Ongoing efforts to promote axonal regeneration after…”
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An improved and simplified protocol to combine Golgi-Cox staining with immunofluorescence and transmission electron microscopy techniques
Published in Neurochemistry international (01-01-2021)“…Approaches utilizing multiple analysis techniques on a single sample are highly desirable in research, especially to reduce the number of animals and obtain…”
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Nanostructures to Engineer 3D Neural‐Interfaces: Directing Axonal Navigation toward Successful Bridging of Spinal Segments
Published in Advanced functional materials (21-03-2018)“…Neural interfaces are the core of prosthetic devices, such as implantable stimulating electrodes or brain–machine interfaces, and are increasingly designed for…”
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Exploiting natural polysaccharides to enhance in vitro bio-constructs of primary neurons and progenitor cells
Published in Acta biomaterialia (01-06-2018)“…[Display omitted] Current strategies in Central Nervous System (CNS) repair focus on the engineering of artificial scaffolds for guiding and promoting neuronal…”
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Correction to Hybrid Interfaces Made of Nanotubes and Backbone-Altered Dipeptides Tune Neuronal Network Architecture
Published in ACS chemical neuroscience (17-11-2021)Get full text
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Altered development in GABA co-release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1(G93A) mouse model of amyotrophic lateral sclerosis
Published in The Journal of physiology (01-07-2016)“…Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in mortality in…”
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Graphene Oxide Nanosheets Target Excitatory Synapses in the Hippocampus: Reversible Down Regulation of Glutamate Neurotransmission In-Vivo
Published in Biophysical journal (02-02-2018)Get full text
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Hybrid Interfaces Made of Nanotubes and Backbone-Altered Dipeptides Tune Neuronal Network Architecture
Published in ACS chemical neuroscience (15-01-2020)“…Peptides constituted of backbone homologated α-amino acids combined with carbon materials offer interesting possibilities in the modulation of cellular…”
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3D meshes of carbon nanotubes guide functional reconnection of segregated spinal explants
Published in Science advances (01-07-2016)“…In modern neuroscience, significant progress in developing structural scaffolds integrated with the brain is provided by the increasing use of nanomaterials…”
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Altered development in GABA co-release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1 super(G93A) mouse model of amyotrophic lateral sclerosis
Published in The Journal of physiology (01-07-2016)“…Key points * Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in…”
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Journal Article -
14
Altered development in GABA co‐release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1 G93A mouse model of amyotrophic lateral sclerosis
Published in The Journal of physiology (01-07-2016)“…Key points Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in…”
Get full text
Journal Article -
15
Altered development in GABA co‐release shapes glycinergic synaptic currents in cultured spinal slices of the SOD1G93A mouse model of amyotrophic lateral sclerosis
Published in The Journal of physiology (01-07-2016)“…Key points Increased environmental risk factors in conjunction with genetic susceptibility have been proposed with respect to the remarkable variations in…”
Get full text
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