Search Results - "Medeiros, Philip J."

Potential involvement of lactate and interleukin-6 in the appetite-regulatory hormonal response to an acute exercise bout by Islam, Hashim, Townsend, Logan K, McKie, Greg L, Medeiros, Philip J, Gurd, Brendon J, Hazell, Tom J

“…High-intensity exercise suppresses appetite partly through changes in peripheral appetite-regulating hormones. Lactate and IL-6 mediate the release of these…”
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Expression of hypoxia inducible factor–dependent neuropeptide Y receptors Y1 and Y5 sensitizes hypoxic cells to NPY stimulation by Medeiros, Philip J., Pascetta, Sydney A., Kirsh, Sarah M., Al-Khazraji, Baraa K., Uniacke, James

“…Neuropeptide Y (NPY) is an abundant neurohormone in the central and peripheral nervous system involved in feeding behavior, energy balance, nociception, and…”
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Point-of-care autofluorescence imaging for real-time sampling and treatment guidance of bioburden in chronic wounds: first-in-human results by DaCosta, Ralph S, Kulbatski, Iris, Lindvere-Teene, Liis, Starr, Danielle, Blackmore, Kristina, Silver, Jason I, Opoku, Julie, Wu, Yichao Charlie, Medeiros, Philip J, Xu, Wei, Xu, Lizhen, Wilson, Brian C, Rosen, Cheryl, Linden, Ron

“…Traditionally, chronic wound infection is diagnosed by visual inspection under white light and microbiological sampling, which are subjective and suboptimal,…”
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Intraoperative fluorescence imaging with aminolevulinic acid detects grossly occult breast cancer: a phase II randomized controlled trial by Ottolino-Perry, Kathryn, Shahid, Anam, DeLuca, Stephanie, Son, Viktor, Sukhram, Mayleen, Meng, Fannong, Liu, Zhihui Amy, Rapic, Sara, Anantha, Nayana Thalanki, Wang, Shirley C, Chamma, Emilie, Gibson, Christopher, Medeiros, Philip J, Majeed, Safa, Chu, Ashley, Wignall, Olivia, Pizzolato, Alessandra, Rosen, Cheryl F, Teene, Liis Lindvere, Starr-Dunham, Danielle, Kulbatski, Iris, Panzarella, Tony, Done, Susan J, Easson, Alexandra M, Leong, Wey L, DaCosta, Ralph S

“…Re-excision due to positive margins following breast-conserving surgery (BCS) negatively affects patient outcomes and healthcare costs. The inability to…”
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Neuropeptide Y stimulates proliferation and migration in the 4T1 breast cancer cell line by Medeiros, Philip J., Al-Khazraji, Baraa K., Novielli, Nicole M., Postovit, Lynne M., Chambers, Ann F., Jackson, Dwayne N.

“…Stress has long been thought of to be associated with increased risk of cancer. Chronic stress is associated with elevated levels of sympathetic…”
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Hypercapnic vs. hypoxic control of cardiovascular, cardiovagal, and sympathetic function by Steinback, Craig D, Salzer, Deborah, Medeiros, Philip J, Kowalchuk, J, Shoemaker, J Kevin

“…We compared the integrated cardiovascular and autonomic responses to hypercapnia and hypoxia to test the hypothesis that these stimuli differentially affect…”
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The Necrosis-Avid Small Molecule HQ4-DTPA as a Multimodal Imaging Agent for Monitoring Radiation Therapy-Induced Tumor Cell Death by Stammes, Marieke A, Maeda, Azusa, Bu, Jiachuan, Scollard, Deborah A, Kulbatski, Iris, Medeiros, Philip J, Sinisi, Riccardo, Dubikovskaya, Elena A, Snoeks, Thomas J A, van Beek, Ermond R, Chan, Alan B, Löwik, Clemens W G M, DaCosta, Ralph S

“…Most effective antitumor therapies induce tumor cell death. Non-invasive, rapid and accurate quantitative imaging of cell death is essential for monitoring…”
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A Simple "Streak Length Method" for Quantifying and Characterizing Red Blood Cell Velocity Profiles and Blood Flow in Rat Skeletal Muscle Arterioles by AL-KHAZRAJI, BARAA K., NOVIELLI, NICOLE M., GOLDMAN, DANIEL, MEDEIROS, PHILIP J., JACKSON, DWAYNE N.

“…Please cite this paper as: Al‐Khazraji BK, Novielli NM, Goldman D, Medeiros PJ, Jackson DN. A simple “Streak Length Method” for quantifying and characterizing…”
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An automated cell-counting algorithm for fluorescently-stained cells in migration assays by Al-Khazraji, Baraa K, Medeiros, Philip J, Novielli, Nicole M, Jackson, Dwayne N

“…A cell-counting algorithm, developed in Matlab®, was created to efficiently count migrated fluorescently-stained cells on membranes from migration assays. At…”
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The exercise-induced suppression of acylated ghrelin is blunted in the luteal phase of the menstrual cycle compared to the follicular phase following vigorous-intensity exercise by Moniz, Sara C., McCarthy, Seth F., Broad, Abigail A., Medeiros, Philip J., Hazell, Tom J.

“…Limited work examining woman's appetite-regulatory response to exercise has been focused on the follicular phase (FP) of the menstrual cycle. This is an…”
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Greater lactate accumulation does not alter peripheral concentrations of key appetite-regulating neuropeptides by McCarthy, Seth F, Bornath, Derek P D, Tucker, Jessica A L, Cohen, Tamara R, Medeiros, Phillip J, Hazell, Tom J

“…The potential mechanisms involved in lactate's role in exercise-induced appetite suppression requires further examination. We used sodium bicarbonate (NaHCO )…”
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Intense interval exercise induces lactate accumulation and a greater suppression of acylated ghrelin compared with submaximal exercise in middle-aged adults by McCarthy, Seth F, Bornath, Derek P D, Jarosz, Claudia, Tucker, Jessica A L, Medeiros, Philip J, Kenno, Kenji A, Hazell, Tom J

“…Exercise in young adults (18-25 yr) suppresses appetite in a dose-response relationship with exercise intensity. Although several mechanisms have been proposed…”
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Interleukin‐6 is not involved in appetite regulation following moderate‐intensity exercise in males with normal weight and obesity by Bornath, Derek P. D., McKie, Greg L., McCarthy, Seth F., Vanderheyden, Luke W., Howe, Greg J., Medeiros, Philip J., Hazell, Tom J.

“…Objective In obesogenic states and after exercise, interleukin (IL)‐6 elevations are established, and IL‐6 is speculated to be an appetite‐regulating…”
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Neuropeptide Y Y5-receptor activation on breast cancer cells acts as a paracrine system that stimulates VEGF expression and secretion to promote angiogenesis by Medeiros, Philip J., Jackson, Dwayne N.

“…•NPY acts in a paracrine manner with 4T1 breast cancer cells to stimulate VEGF production and release.•We found Y5R activation stimulates increases in VEGF…”
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Corrigendum to “The exercise-induced suppression of acylated ghrelin is blunted in the luteal phase of the menstrual cycle compared to the follicular phase following vigorous-intensity exercise” [Appetite 182 (2023) 106425] by Moniz, Sara C., McCarthy, Seth F., Broad, Abigail A., Medeiros, Philip J., Hazell, Tom J.

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Low- and high-load resistance training exercise to volitional fatigue generate exercise-induced appetite suppression by McCarthy, Seth F., Bornath, Derek P.D., Grisebach, Daniel, Tucker, Jessica A.L., Jarosz, Claudia, Ormond, Sion C., Medeiros, Philip J., Hazell, Tom J.

“…Research on exercise-induced appetite suppression often does not include resistance training (RT) exercise and only compared matched volumes. To compare the…”
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Differential changes in appetite hormones post-prandially based on menstrual cycle phase and oral contraceptive use: A preliminary study by McCarthy, Seth F., Townsend, Logan K., McKie, Greg L., Bornath, Derek P.D., Islam, Hashim, Gurd, Brendon J., Medeiros, Philip J., Hazell, Tom J.

“…This was a preliminary study that examined whether appetite regulation is altered during the menstrual cycle or with oral contraceptives. Ten naturally cycling…”
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Physioxic human cell culture improves viability, metabolism, and mitochondrial morphology while reducing DNA damage by Timpano, Sara, Guild, Brianna D., Specker, Erin J., Melanson, Gaelan, Medeiros, Philip J., Sproul, Shannon L. J., Uniacke, James

“…ABSTRACTMulticellular organisms balance oxygen delivery and toxicity by having oxygen pass through several barriers before cellular delivery. In human cell…”
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Pre-diabetes augments neuropeptide Y1- and α1-receptor control of basal hindlimb vascular tone in young ZDF rats by Novielli, Nicole M, Al-Khazraji, Baraa K, Medeiros, Philip J, Goldman, Daniel, Jackson, Dwayne N

“…Peripheral vascular disease in pre-diabetes may involve altered sympathetically-mediated vascular control. Thus, we investigated if pre-diabetes modifies…”
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Autofluorescence imaging device for real-time detection and tracking of pathogenic bacteria in a mouse skin wound model: preclinical feasibility studies by Wu, Yichao Charlie, Kulbatski, Iris, Medeiros, Philip J, Maeda, Azusa, Bu, Jiachuan, Xu, Lizhen, Chen, Yonghong, DaCosta, Ralph S

“…Bacterial infection significantly impedes wound healing. Clinical diagnosis of wound infections is subjective and suboptimal, in part because bacteria are…”
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