Search Results - "Medeiros, Marisa H. G."

Singlet Molecular Oxygen Reactions with Nucleic Acids, Lipids, and Proteins by Di Mascio, Paolo, Martinez, Glaucia R, Miyamoto, Sayuri, Ronsein, Graziella E, Medeiros, Marisa H. G, Cadet, Jean

“…Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently reacting with cellular constituents. The resulting oxidatively…”
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Melanin photosensitization and the effect of visible light on epithelial cells by Chiarelli-Neto, Orlando, Ferreira, Alan Silva, Martins, Waleska Kerllen, Pavani, Christiane, Severino, Divinomar, Faião-Flores, Fernanda, Maria-Engler, Silvya Stuchi, Aliprandini, Eduardo, Martinez, Glaucia R, Di Mascio, Paolo, Medeiros, Marisa H G, Baptista, Maurício S

“…Protecting human skin from sun exposure is a complex issue that involves unclear aspects of the interaction between light and tissue. A persistent…”
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Intermittent fasting results in tissue-specific changes in bioenergetics and redox state by Chausse, Bruno, Vieira-Lara, Marcel A, Sanchez, Angélica B, Medeiros, Marisa H G, Kowaltowski, Alicia J

“…Intermittent fasting (IF) is a dietary intervention often used as an alternative to caloric restriction (CR) and characterized by 24 hour cycles alternating ad…”
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Singlet molecular oxygen generation by light-activated DHN-melanin of the fungal pathogen Mycosphaerella fijiensis in black Sigatoka disease of bananas by Beltrán-García, Miguel J, Prado, Fernanda M, Oliveira, Marilene S, Ortiz-Mendoza, David, Scalfo, Alexsandra C, Pessoa, Jr, Adalberto, Medeiros, Marisa H G, White, James F, Di Mascio, Paolo

“…In pathogenic fungi, melanin contributes to virulence, allowing tissue invasion and inactivation of the plant defence system, but has never been implicated as…”
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DNA damage by singlet oxygen and cellular protective mechanisms by Agnez-Lima, Lucymara F., Melo, Julliane T.A., Silva, Acarízia E., Oliveira, Ana Helena S., Timoteo, Ana Rafaela S., Lima-Bessa, Keronninn M., Martinez, Glaucia R., Medeiros, Marisa H.G., Di Mascio, Paolo, Galhardo, Rodrigo S., Menck, Carlos F.M.

“…Reactive oxygen species, as singlet oxygen (1O2) and hydrogen peroxide, are continuously generated by aerobic organisms, and react actively with biomolecules…”
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DNA Adduct Formation in the Lungs and Brain of Rats Exposed to Low Concentrations of [13C2]‑Acetaldehyde by Sanchez, Angélica B, Garcia, Camila C. M, Freitas, Florêncio P, Batista, Guilherme L, Lopes, Fernando S, Carvalho, Victor H, Ronsein, Graziella E, Gutz, Ivano G. R, Di Mascio, Paolo, Medeiros, Marisa H. G

“…Air pollution is a major environmental risk for human health. Acetaldehyde is present in tobacco smoke and vehicle exhaust. In this study, we show that…”
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The development of a specific and sensitive LC-MS-based method for the detection and quantification of hydroperoxy- and hydroxydocosahexaenoic acids as a tool for lipidomic analysis by Derogis, Priscilla B M C, Freitas, Florêncio P, Marques, Anna S F, Cunha, Daniela, Appolinário, Patricia P, de Paula, Fernando, Lourenço, Tiago C, Murgu, Michael, Di Mascio, Paolo, Medeiros, Marisa H G, Miyamoto, Sayuri

“…Docosahexaenoic acid (DHA) is an n-3 polyunsaturated fatty acid that is highly enriched in the brain, and the oxidation products of DHA are present or…”
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Singlet Oxygen Oxidation of Isolated and Cellular DNA: Product Formation and Mechanistic Insights by Cadet, Jean, Ravanat, Jean-Luc, Martinez, Glaucia R., Medeiros, Marisa H. G., Di Mascio, Paolo

“…This survey focuses on recent aspects of the singlet oxygen oxidation of the guanine moiety of nucleosides, oligonucleotides, isolated and cellular DNA that…”
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Alterations in lipid metabolism of spinal cord linked to amyotrophic lateral sclerosis by Chaves-Filho, Adriano Britto, Pinto, Isabella Fernanda Dantas, Dantas, Lucas Souza, Xavier, Andre Machado, Inague, Alex, Faria, Rodrigo Lucas, Medeiros, Marisa H. G., Glezer, Isaias, Yoshinaga, Marcos Yukio, Miyamoto, Sayuri

“…Amyotrophic lateral sclerosis (ALS) is characterized by progressive loss of upper and lower motor neurons leading to muscle paralysis and death. While a link…”
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Formation and repair of oxidatively generated damage in cellular DNA by Cadet, Jean, Davies, Kelvin J.A., Medeiros, Marisa HG, Di Mascio, Paolo, Wagner, J. Richard

“…In this review article, emphasis is placed on the critical survey of available data concerning modified nucleobase and 2-deoxyribose products that have been…”
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Mild mitochondrial uncoupling in mice affects energy metabolism, redox balance and longevity by Caldeira da Silva, Camille C., Cerqueira, Fernanda M., Barbosa, Lívea F., Medeiros, Marisa H. G., Kowaltowski, Alicia J.

“…Summary Caloric restriction is the most effective non‐genetic intervention to enhance lifespan known to date. A major research interest has been the…”
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Exocyclic DNA Adducts as Biomarkers of Lipid Oxidation and Predictors of Disease. Challenges in Developing Sensitive and Specific Methods for Clinical Studies by Medeiros, Marisa H. G

“…Exocyclic DNA adducts are emerging as potential new tools for the study of oxidative stress-related diseases as well as the determination of cancer etiology…”
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Singlet oxygen‐induced protein aggregation: Lysozyme crosslink formation and nLC‐MS/MS characterization by Marques, Emerson Finco, Medeiros, Marisa H.G., Di Mascio, Paolo

“…Singlet molecular oxygen (1O2) has been associated with a number of physiological processes. Despite the recognized importance of 1O2‐mediated protein…”
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Iron Deficiency Generates Oxidative Stress and Activation of the SOS Response in Caulobacter crescentus by Leaden, Laura, Silva, Larissa G, Ribeiro, Rodolfo A, Dos Santos, Naara M, Lorenzetti, Alan P R, Alegria, Thiago G P, Schulz, Mariane L, Medeiros, Marisa H G, Koide, Tie, Marques, Marilis V

“…In , iron metabolism is mainly controlled by the transcription factor Fur (ferric uptake regulator). Iron-bound Fur represses genes related to iron uptake and…”
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Generation of Singlet Molecular Oxygen by Lipid Hydroperoxides and Nitronium Ion by Prado, Fernanda M., Scalfo, Alexsandra C., Miyamoto, Sayuri, Medeiros, Marisa H.G., Di Mascio, Paolo

“…Singlet molecular oxygen is a reactive species involved in biological oxidative processes. The major cellular targets of singlet molecular oxygen are…”
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Heck reaction synthesis of anthracene and naphthalene derivatives as traps and clean chemical sources of singlet molecular oxygen in biological systems by Oliveira, Marilene Silva, Chorociejus, Gabriel, Angeli, José Pedro F, Vila Verde, Giuliana, Aquino, Gilberto L B, Ronsein, Graziella E, Oliveira, Maurício César Bof de, Barbosa, Livea F, Medeiros, Marisa H G, Greer, Alexander, Di Mascio, Paolo

“…Studies have previously shown that anthracene and naphthalene derivatives serve as compounds for trapping and chemically generating singlet molecular oxygen…”
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Excited singlet molecular O2 (1Δg) is generated enzymatically from excited carbonyls in the dark by Mano, Camila M., Prado, Fernanda M., Massari, Júlio, Ronsein, Graziella E., Martinez, Glaucia R., Miyamoto, Sayuri, Cadet, Jean, Sies, Helmut, Medeiros, Marisa H. G., Bechara, Etelvino J. H., Di Mascio, Paolo

“…In mammalian tissues, ultraweak chemiluminescence arising from biomolecule oxidation has been attributed to the radiative deactivation of singlet molecular…”
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Lysozyme oxidation by singlet molecular oxygen: Peptide characterization using [18O]‐labeling oxygen and nLC‐MS/MS by Marques, Emerson Finco, Medeiros, Marisa H.G., Di Mascio, Paolo

“…Singlet molecular oxygen (1O2) is generated in biological systems and reacts with different biomolecules. Proteins are a major target for 1O2, and His, Tyr,…”
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Generation of Cholesterol Carboxyaldehyde by the Reaction of Singlet Molecular Oxygen [O2 (1Δg)] as Well as Ozone with Cholesterol by Uemi, Miriam, Ronsein, Graziella E, Miyamoto, Sayuri, Medeiros, Marisa H. G, Di Mascio, Paolo

“…A few years ago, it was reported that ozone is produced in human atherosclerotic arteries, on the basis of the identification of…”
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The molecular structure of β-alanine is resistant to sterilising doses of gamma radiation by Gonçalves, Lívia de Souza, Franchi, Mariana, Mathor, Monica B, Lugao, Ademar B, Carvalho, Victor H, Medeiros, Marisa H G, Artioli, Guilherme Giannini, Varca, Gustavo H C

“…β-alanine is the rate-limiting point for the endogenous synthesis of carnosine in skeletal muscle. Carnosine has a wide range of implications for health,…”
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