Search Results - "Medeiros, Lea A."

Mir-290–295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects by Medeiros, Lea A, Dennis, Lucas M, Gill, Mark E, Houbaviy, Hristo, Markoulaki, Styliani, Fu, Dongdong, White, Amy C, Kirak, Oktay, Sharp, Phillip A, Page, David C, Jaenisch, Rudolf

“…Mir-290 through mir-295 (mir-290–295) is a mammalian-specific microRNA (miRNA) cluster that, in mice, is expressed specifically in early embryos and embryonic…”
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A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells by Zheng, Grace X Y, Ravi, Arvind, Calabrese, J Mauro, Medeiros, Lea A, Kirak, Oktay, Dennis, Lucas M, Jaenisch, Rudolf, Burge, Christopher B, Sharp, Phillip A

“…MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal…”
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Fibrillar Amyloid Protein Present in Atheroma Activates CD36 Signal Transduction by Medeiros, Lea A., Khan, Tayeba, El Khoury, Joseph B., Pham, Chi L.L., Hatters, Danny M., Howlett, Geoffrey J., Lopez, Roland, O’Brien, Kevin D., Moore, Kathryn J.

“…The self-association of proteins to form amyloid fibrils has been implicated in the pathogenesis of a number of diseases including Alzheimer’s, Parkinson’s,…”
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Polycomb complexes repress developmental regulators in murine embryonic stem cells by Vidal, Miguel, Levine, Stuart S, Zeitlinger, Julia, Otte, Arie P, Gifford, David K, Bell, George W, Plath, Kathrin, Medeiros, Lea A, Jaenisch, Rudolf, Boyer, Laurie A, Wernig, Marius, Tajonar, Adriana, Ray, Mridula K, Brambrink, Tobias, Young, Richard A, Lee, Tong Ihn

“…The mechanisms by which embryonic stem (ES) cells self-renew while maintaining the ability to differentiate into virtually all adult cell types are not well…”
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beta-Amyloid promotes accumulation of lipid peroxides by inhibiting CD36-mediated clearance of oxidized lipoproteins by Kunjathoor, Vidya V, Tseng, Anita A, Medeiros, Lea A, Khan, Tayeba, Moore, Kathryn J

“…BACKGROUND: Recent studies suggest that hypercholesterolemia, an established risk factor for atherosclerosis, is also a risk factor for Alzheimer's disease…”
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A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid by Moore, Kathryn J., El Khoury, Joseph, Medeiros, Lea A., Terada, Kinya, Geula, Changiz, Luster, Andrew D., Freeman, Mason W.

“…β-Amyloid accumulation is associated with pathologic changes in the brain in Alzheimer's disease and has recently been identified in plaques of another chronic…”
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A Latent Pro-Survival Function for the Mir-290-295 Cluster in Mouse Embryonic Stem Cells: e1002054 by Zheng, Grace XY, Ravi, Arvind, Calabrese, J Mauro, Medeiros, Lea A, Kirak, Oktay, Dennis, Lucas M, Jaenisch, Rudolf, Burge, Christopher B, Sharp, Phillip A

“…MicroRNAs (miRNAs) post-transcriptionally regulate the expression of thousands of distinct mRNAs. While some regulatory interactions help to maintain basal…”
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A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of β-Amyloid by Kathryn J. Moore, Joseph El Khoury, Lea A. Medeiros, Kinya Terada, Changiz Geula, Andrew D. Luster, Mason W. Freeman

“…β-Amyloid accumulation is associated with pathologic changes in the brain in Alzheimer's disease and has recently been identified in plaques of another…”
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