Search Results - "Medeiros, Daniel"
-
1
The deuterostome context of chordate origins
Published in Nature (London) (23-04-2015)“…Our understanding of vertebrate origins is powerfully informed by comparative morphology, embryology and genomics of chordates, hemichordates and echinoderms,…”
Get full text
Journal Article -
2
Linking Vertebrate Gene Duplications to the New Head Hypothesis
Published in Biology (Basel, Switzerland) (01-09-2023)“…Vertebrates have diverse morphologies and various anatomical novelties that set them apart from their closest invertebrate relatives. A conspicuous head…”
Get full text
Journal Article -
3
BMP, Wnt and FGF signals are integrated through evolutionarily conserved enhancers to achieve robust expression of Pax3 and Zic genes at the zebrafish neural plate border
Published in Development (Cambridge) (15-11-2012)“…Neural crest cells generate a range of cells and tissues in the vertebrate head and trunk, including peripheral neurons, pigment cells, and cartilage. Neural…”
Get full text
Journal Article -
4
Evolution of the endothelin pathway drove neural crest cell diversification
Published in Nature (London) (24-09-2020)“…Neural crest cells (NCCs) are migratory, multipotent embryonic cells that are unique to vertebrates and form an array of clade-defining adult features. The…”
Get full text
Journal Article -
5
Evolution of the new vertebrate head by co-option of an ancient chordate skeletal tissue
Published in Nature (London) (26-02-2015)“…A tissue with many of the defining features of vertebrate cellular cartilage is shown to form transiently in larvae of the invertebrate chordate amphioxus,…”
Get full text
Journal Article -
6
Lamprey lecticans link new vertebrate genes to the origin and elaboration of vertebrate tissues
Published in Developmental biology (01-08-2021)“…The evolution of vertebrates from an invertebrate chordate ancestor involved the evolution of new organs, tissues, and cell types. It was also marked by the…”
Get full text
Journal Article -
7
Biochemical and Biological Profile of Parotoid Secretion of the Amazonian Rhinella marina (Anura: Bufonidae)
Published in BioMed research international (01-01-2019)“…Skin secretions of frogs have a high chemical complexity. They have diverse types of biomolecules, such as proteins, peptides, biogenic amines, and alkaloids…”
Get full text
Journal Article -
8
Evolution of vertebrate gill covers via shifts in an ancient Pou3f3 enhancer
Published in Proceedings of the National Academy of Sciences - PNAS (06-10-2020)“…Whereas the gill chambers of jawless vertebrates open directly into the environment, jawed vertebrates evolved skeletal appendages that drive oxygenated water…”
Get full text
Journal Article -
9
Epilepsy as a dynamical system, a most needed paradigm shift in epileptology
Published in Epilepsy & behavior (01-08-2021)“…The idea of the epileptic brain being highly excitable and facilitated to synchronic activity has guided pharmacological treatment since the early twentieth…”
Get full text
Journal Article -
10
A mouse model of sleep disorders in Parkinson’s disease showing distinct effects of dopamine D2-like receptor activation
Published in Progress in neurobiology (01-12-2023)“…Excessive daytime sleepiness (EDS) and sleep fragmentation are often observed in Parkinson’s disease (PD) patients and are poorly understood despite their…”
Get full text
Journal Article -
11
CRISPR/Cas9-mediated mutagenesis in the sea lamprey Petromyzon marinus: a powerful tool for understanding ancestral gene functions in vertebrates
Published in Development (Cambridge) (01-12-2015)“…Lamprey is one of only two living jawless vertebrates, a group that includes the first vertebrates. Comparisons between lamprey and jawed vertebrates have…”
Get full text
Journal Article -
12
Synergism of in vitro plasmodicidal activity of phospholipase A2 isoforms isolated from panamanian Bothrops asper venom
Published in Chemico-biological interactions (01-09-2021)“…Bothrops asper is one of the most important snake species in Central America, mainly because of its medical importance in countries like Ecuador, Panama and…”
Get full text
Journal Article -
13
Effects of early or late prenatal immune activation in mice on behavioral and neuroanatomical abnormalities relevant to schizophrenia in the adulthood
Published in International journal of developmental neuroscience (01-05-2017)“…•Poly I:C injection during gestation alters locomotor activity of the adult offspring.•Poly I:C injection during gestation reduces glucose preference of the…”
Get full text
Journal Article -
14
Kub: Enabling Elastic HPC Workloads on Containerized Environments
Published in 2023 IEEE 35th International Symposium on Computer Architecture and High Performance Computing (SBAC-PAD) (17-10-2023)“…The conventional model of resource allocation in HPC systems is static. Thus, a job cannot leverage newly available resources in the system or release…”
Get full text
Conference Proceeding -
15
Variability of Trends in Precipitation across the Amazon River Basin Determined from the CHIRPS Precipitation Product and from Station Records
Published in Water (Basel) (01-05-2020)“…The Amazon River Basin is the largest rainforest in the world. Long-term changes in precipitation trends in the basin can affect the continental water balance…”
Get full text
Journal Article -
16
Cartilage diversification and modularity drove the evolution of the ancestral vertebrate head skeleton
Published in EvoDevo (05-05-2023)“…The vertebrate head skeleton has evolved a myriad of forms since their divergence from invertebrate chordates. The connection between novel gene expression and…”
Get full text
Journal Article -
17
Sublayer- and cell-type-specific neurodegenerative transcriptional trajectories in hippocampal sclerosis
Published in Cell reports (Cambridge) (08-06-2021)“…Hippocampal sclerosis, the major neuropathological hallmark of temporal lobe epilepsy, is characterized by different patterns of neuronal loss. The mechanisms…”
Get full text
Journal Article -
18
Religiosity and religious and spiritual struggle and their association to depression and anxiety among adolescents admitted to inpatient psychiatric units
Published in Journal of health care chaplaincy (2023)“…This study examines the relationship between religious and spiritual (R/S) struggle and religiosity with depression and anxiety in adolescents admitted to…”
Get full text
Journal Article -
19
Roles for FGF in lamprey pharyngeal pouch formation and skeletogenesis highlight ancestral functions in the vertebrate head
Published in Development (Cambridge) (01-02-2014)“…A defining feature of vertebrates (craniates) is a pronounced head supported and protected by a cellularized endoskeleton. In jawed vertebrates (gnathostomes),…”
Get full text
Journal Article -
20
The Composition and Cellular Sources of CSPGs in the Glial Scar After Spinal Cord Injury in the Lamprey
Published in Frontiers in molecular neuroscience (27-06-2022)“…Axon regrowth after spinal cord injury (SCI) is inhibited by several types of inhibitory extracellular molecules in the central nervous system (CNS), including…”
Get full text
Journal Article