Search Results - "Medei, Emiliano"

Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice by Monnerat, Gustavo, Alarcón, Micaela L., Vasconcellos, Luiz R., Hochman-Mendez, Camila, Brasil, Guilherme, Bassani, Rosana A., Casis, Oscar, Malan, Daniela, Travassos, Leonardo H., Sepúlveda, Marisa, Burgos, Juan Ignacio, Vila-Petroff, Martin, Dutra, Fabiano F., Bozza, Marcelo T., Paiva, Claudia N., Carvalho, Adriana Bastos, Bonomo, Adriana, Fleischmann, Bernd K., de Carvalho, Antonio Carlos Campos, Medei, Emiliano

“…Diabetes mellitus (DM) encompasses a multitude of secondary disorders, including heart disease. One of the most frequent and potentially life threatening…”
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IL-1β Blockade Attenuates Thrombosis in a Neutrophil Extracellular Trap-Dependent Breast Cancer Model by Gomes, Tainá, Várady, Carolina B S, Lourenço, André L, Mizurini, Daniella M, Rondon, Araci M R, Leal, Ana C, Gonçalves, Barbara S, Bou-Habib, Dumith Chequer, Medei, Emiliano, Monteiro, Robson Q

“…Cancer patients are at increased risk of developing thrombosis, comorbidity that has been associated with increased neutrophil counts and the formation of…”
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Author Correction: Macrophage-dependent IL-1β production induces cardiac arrhythmias in diabetic mice by Monnerat, Gustavo, Alarcón, Micaela L., Vasconcellos, Luiz R., Hochman-Mendez, Camila, Brasil, Guilherme, Bassani, Rosana A., Casis, Oscar, Malan, Daniela, Travassos, Leonardo H., Sepúlveda, Marisa, Burgos, Juan Ignacio, Vila-Petroff, Martin, Dutra, Fabiano F., Bozza, Marcelo T., Paiva, Claudia N., Carvalho, Adriana Bastos, Bonomo, Adriana, Fleischmann, Bernd K., de Carvalho, Antonio Carlos Campos, Medei, Emiliano

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Methylmercury Poisoning Induces Cardiac Electrical Remodeling and Increases Arrhythmia Susceptibility and Mortality by Santos Ruybal, Mara Cristina P, Gallego, Monica, Sottani, Thais Bazoti B, Medei, Emiliano H, Casis, Oscar, Nascimento, Jose Hamilton M

“…This study aims to investigate the cardiac electrical remodeling associated with intoxication by methylmercury (MeHg). We evaluated the chronic effects of MeHg…”
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Toll-like receptor 4 activation promotes cardiac arrhythmias by decreasing the transient outward potassium current (Ito ) through an IRF3-dependent and MyD88-independent pathway by Monnerat-Cahli, Gustavo, Alonso, Hiart, Gallego, Monica, Alarcón, Micaela Lopez, Bassani, Rosana A, Casis, Oscar, Medei, Emiliano

“…Abstract Cardiac arrhythmias are one of the main causes of death worldwide. Several studies have shown that inflammation plays a key role in different cardiac…”
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ROS and Trypanosoma cruzi: Fuel to infection, poison to the heart by Paiva, Claudia N, Medei, Emiliano, Bozza, Marcelo T

“…The activation of macrophage respiratory burst in response to infection with Trypanosoma cruzi inflicts oxidative damage to the host's tissues. For decades,…”
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High Thyrotropin Is Critical for Cardiac Electrical Remodeling and Arrhythmia Vulnerability in Hypothyroidism by Fernandez-Ruocco, Julieta, Gallego, Monica, Rodriguez-de-Yurre, Ainhoa, Zayas-Arrabal, Julian, Echeazarra, Leyre, Alquiza, Amaia, Fernández-López, Victor, Rodriguez-Robledo, Juan M, Brito, Oscar, Schleier, Ygor, Sepulveda, Marisa, Oshiyama, Natalia F, Vila-Petroff, Martin, Bassani, Rosana A, Medei, Emiliano H, Casis, Oscar

“…Hypothyroidism, the most common endocrine disease, induces cardiac electrical remodeling that creates a substrate for ventricular arrhythmias. Recent studies…”
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Resveratrol Reverses Functional Chagas Heart Disease in Mice by Vilar-Pereira, Glaucia, Carneiro, Vitor C, Mata-Santos, Hilton, Vicentino, Amanda R R, Ramos, Isalira P, Giarola, Naira L L, Feijó, Daniel F, Meyer-Fernandes, José R, Paula-Neto, Heitor A, Medei, Emiliano, Bozza, Marcelo T, Lannes-Vieira, Joseli, Paiva, Claudia N

“…Chronic chagasic cardiomyopathy (CCC) develops years after acute infection by Trypanosoma cruzi and does not improve after trypanocidal therapy, despite…”
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Knockout of Toll-Like Receptors 2 and 4 Prevents Renal Ischemia-Reperfusion-Induced Cardiac Hypertrophy in Mice by Trentin-Sonoda, Mayra, da Silva, Rogério Cirino, Kmit, Fernanda Vieira, Abrahão, Mariana Vieira, Monnerat Cahli, Gustavo, Brasil, Guilherme Visconde, Muzi-Filho, Humberto, Silva, Paulo André, Tovar-Moll, Fernanda Freire, Vieyra, Adalberto, Medei, Emiliano, Carneiro-Ramos, Marcela Sorelli

“…We investigated whether the pathways linked to Toll-like receptors 2 and 4 (TLRs) are involved in renal ischemia-reperfusion (I/R)-induced cardiac hypertrophy…”
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R534C mutation in hERG causes a trafficking defect in iPSC-derived cardiomyocytes from patients with type 2 long QT syndrome by Mesquita, Fernanda C. P., Arantes, Paulo C., Kasai-Brunswick, Tais H., Araujo, Dayana S., Gubert, Fernanda, Monnerat, Gustavo, Silva dos Santos, Danúbia, Neiman, Gabriel, Leitão, Isabela C., Barbosa, Raiana A. Q., Coutinho, Jorge L., Vaz, Isadora M., dos Santos, Marcus N., Borgonovo, Tamara, Cruz, Fernando E. S., Miriuka, Santiago, Medei, Emiliano H., Campos de Carvalho, Antonio C., Carvalho, Adriana B.

“…Patient-specific cardiomyocytes obtained from induced pluripotent stem cells (CM-iPSC) offer unprecedented mechanistic insights in the study of inherited…”
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IL-1β is not critical to chronic heart dysfunction in mice with Chagas disease by Sousa Oliveira, Camila Victória, Moreno-Loaiza, Oscar, Figueiredo-Vanzan, Daniel, Peroba Ramos, Isalira, Mata-Santos, Hilton, Torres Bozza, Marcelo, Neto Paiva, Claudia, Medei, Emiliano

“…Long after infection, 40% of individuals develop a progressive chronic chagasic cardiomyopathy (CCC), with systolic dysfunction and arrhythmias. Since we…”
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Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart by Malagueta-Vieira, Layse, Fernández-Ruocco, Julieta, Hortigón-Vinagre, María P, Zamora, Víctor, Zayas-Arrabal, Julián, Echeazarra, Leyre, Smith, Godfrey L, Vila Petroff, Martín, Medei, Emiliano, Casis, Óscar, Gallego, Mónica

“…Metformin is the first choice drug for the treatment of type 2 diabetes due to positive results in reducing hyperglycaemia and insulin resistance. However,…”
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Non-β-Blocking Carvedilol Analog, VK-II-86, Prevents Ouabain-Induced Cardiotoxicity by Gonano, Luis A., Sepúlveda, Marisa, Morell, Malena, Toteff, Tamara, Racioppi, María Florencia, Lascano, Elena, Negroni, Jorge, Ruocco, María Julieta Fernández, Medei, Emiliano, Neiman, Gabriel, Miriuka, Santiago G., Back, Thomas G., Chen, S. R. Wayne, Mattiazzi, Alicia, Petroff, Martin Vila

“…Background: It has been shown that carvedilol and its non β-blocking analog, VK-II-86, inhibit spontaneous Ca2+ release from the sarcoplasmic reticulum (SR)…”
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Influence of Stem Cell Therapy on Thyroid Function and Reactive Oxygen Species Production in Diabetic Rats by da Silva, Diorney Luiz Souza Gran, de Freitas, Mariana Lopes, Cahil, Gustavo Monnerat, de São José, Vitória Santório, Neto, Felippe Mousovich, Cardoso, Ricardo Cortez, da Costa, Vânia Maria Correa, Fortunato, Rodrigo Soares, de Carvalho, Denise Pires, Medei, Emiliano Horácio, Ferreira, Andrea Claudia Freitas

“…Cell therapy with mesenchymal stem cells (MSC) has been proposed for the treatment of diabetes mellitus (DM). It is known that the prevalence of thyroid…”
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Monitoring of the Parasite Load in the Digestive Tract of Rhodnius prolixus by Combined qPCR Analysis and Imaging Techniques Provides New Insights into the Trypanosome Life Cycle by Dias, Felipe de Almeida, Guerra, Barbara, Vieira, Larissa Rezende, Perdomo, Hugo Diego, Gandara, Ana Caroline Paiva, Amaral, Raquel Juliana Vionette do, Vollú, Renata Estebanez, Gomes, Suzete Araujo Oliveira, Lara, Flavio Alves, Sorgine, Marcos Henrique Ferreira, Medei, Emiliano, de Oliveira, Pedro Lagerblad, Salmon, Didier

“…Here we report the monitoring of the digestive tract colonization of Rhodnius prolixus by Trypanosoma cruzi using an accurate determination of the parasite…”
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Heat Shock Proteins: Connectors between Heart and Kidney by Junho, Carolina Victória Cruz, Azevedo, Carolina Amaral Bueno, da Cunha, Regiane Stafim, de Yurre, Ainhoa Rodriguez, Medei, Emiliano, Stinghen, Andréa Emilia Marques, Carneiro-Ramos, Marcela Sorelli

“…Over the development of eukaryotic cells, intrinsic mechanisms have been developed in order to provide the ability to defend against aggressive agents. In this…”
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Sheltered in Stromal Tissue Cells, Trypanosoma cruzi Orchestrates Inflammatory Neovascularization via Activation of the Mast Cell Chymase Pathway by Vellasco, Lucas, Svensjö, Erik, Bulant, Carlos Alberto, Blanco, Pablo Javier, Nogueira, Fábio, Domont, Gilberto, de Almeida, Natália Pinto, Nascimento, Clarissa Rodrigues, Silva-Dos-Santos, Danielle, Carvalho-Pinto, Carla Eponina, Medei, Emiliano Horácio, Almeida, Igor C, Scharfstein, Julio

“…Microangiopathy may worsen the clinical outcome of Chagas disease. Given the obstacles to investigating the dynamics of inflammation and angiogenesis in heart…”
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Value of 123I-MIBG SPECT for the assessment of dysautonomia in patients with long COVID by Xavier de Brito, Adriana S., Bronchtein, Ana Inês, Schaustz, Eduardo B., Glavam, Adriana P., Pinheiro, Martha Valéria T., Secco, José Carlos P., Camargo, Gabriel C., Almeida, Sergio A., Quintella, Tayene A., Albuquerque, Denilson C., Luiz, Ronir R., Medei, Emiliano, Souza, Olga F., Sales, Allan Robson K., Sousa, Andrea S., Rosado-de-Castro, Paulo Henrique, Moll-Bernardes, Renata J.

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Water-soluble lectin (WSMoL) from Moringa oleifera seeds treatment recovers glycemic levels and improves left ventricular ejection fraction on Type-2 Diabetes mice model by Vera-Nuñez, Narendra, Guirao, Ainhoa R Y, Silva, José Dayvid F DA, Ramos, Isalira P, Torres, Marília K S, Coelho, Luana Cassandra B B, Napoleão, Thiago Henrique, Paiva, Patrícia Maria G, Medei, Emiliano

“…Moringa oleifera, a plant widely used in traditional medicine as well as for water purification, contains a lectin on its seeds named WSMoL which modulates…”
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Cardiac remodeling and inflammation detected by magnetic resonance imaging in COVID-19 survivors by Schaustz, Eduardo B., Secco, José Carlos P., Barroso, Julia M., Ferreira, Juliana R., Tortelly, Mariana B., Pimentel, Adriana L., Figueiredo, Ana Cristina B.S., Albuquerque, Denilson C., Sales, Allan R. Kluser, Rosado de-Castro, Paulo H., Pinheiro, Martha V.T., Souza, Olga F., Medei, Emiliano, Luiz, Ronir R., Silvestre-Sousa, Andréa, Camargo, Gabriel C., Moll-Bernardes, Renata

“…[Display omitted] Concerns have been raised about cardiac inflammation in patients with long COVID-19, particularly those with myocardial injury during the…”
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