Search Results - "Medack, Anja"

Dysfunctional nitric oxide signalling increases risk of myocardial infarction by Erdmann, Jeanette, Stark, Klaus, Esslinger, Ulrike B., Rumpf, Philipp Moritz, Koesling, Doris, de Wit, Cor, Kaiser, Frank J., Braunholz, Diana, Medack, Anja, Fischer, Marcus, Zimmermann, Martina E., Tennstedt, Stephanie, Graf, Elisabeth, Eck, Sebastian, Aherrahrou, Zouhair, Nahrstaedt, Janja, Willenborg, Christina, Bruse, Petra, Brænne, Ingrid, Nöthen, Markus M., Hofmann, Per, Braund, Peter S., Mergia, Evanthia, Reinhard, Wibke, Burgdorf, Christof, Schreiber, Stefan, Balmforth, Anthony J., Hall, Alistair S., Bertram, Lars, Steinhagen-Thiessen, Elisabeth, Li, Shu-Chen, März, Winfried, Reilly, Muredach, Kathiresan, Sekar, McPherson, Ruth, Walter, Ulrich, Ott, Jurg, Samani, Nilesh J., Strom, Tim M., Meitinger, Thomas, Hengstenberg, Christian, Schunkert, Heribert

“…Two private, heterozygous mutations in two functionally related genes, GUCY1A3 and CCT7 , are identified in an extended family with myocardial infarction;…”
Get full text

Whole-exome sequencing in an extended family with myocardial infarction unmasks familial hypercholesterolemia by Brænne, Ingrid, Reiz, Benedikt, Medack, Anja, Kleinecke, Mariana, Fischer, Marcus, Tuna, Salih, Hengstenberg, Christian, Deloukas, Panos, Erdmann, Jeanette, Schunkert, Heribert

“…Familial hypercholesterolemia (FH) is an autosomal-dominant disease leading to markedly elevated low-density lipoprotein (LDL) cholesterol levels and increased…”
Get full text

Transcriptional activation of Odf2/Cenexin by cell cycle arrest and the stress activated signaling pathway (JNK pathway) by Pletz, Nadin, Medack, Anja, Rieß, Eva Maria, Yang, Kefei, Kazerouni, Zahra Basir, Hüber, Daniela, Hoyer-Fender, Sigrid

“…The centrosome/basal body protein ODF2/Cenexin is necessary for the formation of the primary cilium. Primary cilia are essential organelles that sense and…”
Get full text

Abstract 19822: Ldlr Splice-Site Mutation (ivs9-1g>A) Identified by Whole-Exome Sequencing in an Extended Family with Myocardial Infarction by Brænne, Ingrid, Medack, Anja, Stark, Klaus, Field, Sarah, Tuna, Salih, Deloukas, Panos, Samani, Nilesh J, Schunkert, Heribert, Hengstenberg, Christian, Erdmann, Jeanette

“…Abstract only Introduction: Large genome-wide association studies have identified a number of chromosomal loci for CAD and MI, which display clear significance…”
Get full text

Abstract 19823: Whole-Exome Sequencing in an Extended Family with Myocardial Infarction Identified a Potential Functional Mutation in PDE5A by Brænne, Ingrid, Medack, Anja, Stark, Klaus, Field, Sarah, Tuna, Salih, Deloukas, Panos, Samani, Nilesh J, Hengstenberg, Christian, Schunkert, Heribert, Erdmann, Jeanette

“…Abstract only Objective: Despite the enormous success of genome-wide association studies (GWAS), only a small fraction of the expected heritability for CAD and…”
Get full text

Genetic variation in the arachidonate 5-lipoxygenase-activating protein (ALOX5AP) is associated with myocardial infarction in the German population by Linsel-Nitschke, Patrick, Götz, Anika, Medack, Anja, König, Inke R, Bruse, Petra, Lieb, Wolfgang, Mayer, Björn, Stark, Klaus, Hengstenberg, Christian, Fischer, Marcus, Baessler, Andrea, Ziegler, Andreas, Schunkert, Heribert, Erdmann, Jeanette

“…Genetic variation in the genes ALOX5AP (arachidonate 5-lipoxygenase-activating protein) and LTA4H (leukotriene A4 hydrolase) has previously been shown to…”
Get more information

Abstract 3452: The Common Variant Rs9939609 In The FTO Gene Is Associated With Myocardial Infarction In Two Large German Populations (German Family MI Study And KORA-B) by Erdmann, Jeanette, Götz, Anika, Bruse, Petra, Medack, Anja, Lieb, Wolfgang, Fischer, Marcus, Baessler, Andrea, Stark, Klaus, Hengstenberg, Christian, Ziegler, Andreas, Schunkert, Heribert

“…Abstract only Very recently, a genome-wide search for type 2 diabetes susceptibility genes identified a common variant in the FTO gene that predisposes to…”
Get full text