Search Results - "Mebarki, Sihem"
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Tenascin-W Is a Novel Stromal Marker in Biliary Tract Cancers
Published in Frontiers in immunology (22-02-2021)“…Extrahepatic cancers of the biliary system are typically asymptomatic until after metastasis, which contributes to their poor prognosis. Here we examined…”
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“Fibrous nests” in human hepatocellular carcinoma express a Wnt-induced gene signature associated with poor clinical outcome
Published in The international journal of biochemistry & cell biology (01-12-2016)“…“Fibrous nests”: HCCs containing fibrous nests are enriched in Wnt signals. These are associated with markers of mesenchymal commitment, stem cells and…”
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De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas
Published in Oncotarget (28-06-2016)“…About 20% hepatocellular carcinomas (HCCs) display wild-type β-catenin, enhanced Wnt signaling, hepatocyte dedifferentiation and bad outcome, suggesting a…”
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Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin
Published in Oncogene (27-01-2011)“…Constitutive activation of Wnt/β-catenin signaling in cancer results from mutations in pathway components, which frequently coexist with autocrine Wnt…”
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Blocking Wnt signaling by SFRP-like molecules inhibits in vivo cell proliferation and tumor growth in cells carrying active β-catenin: An SFRP-like frizzled motif blocks tumor growth
Published in Oncogene (27-01-2011)“…Constitutive activation of Wnt/β-catenin signaling in cancer results from mutations in pathway components, which frequently coexist with autocrine Wnt…”
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Journal Article