Search Results - "Meats, J. E"

Human synovium releases a factor which stimulates chondrocyte production of PGE and plasminogen activator by Meats, J. E, McGuire, M. B, Russell, R. G. G

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Is intracellular pH a coupling factor in nutrient-stimulated pancreatic islets? by Best, L, Bone, E A, Meats, J E, Tomlinson, S

“…Intracellular pH (pHi) was monitored in dispersed pancreatic islet cells from rats using the fluorescent dye 2'7'bis-carboxyethyl-5'(6')-carboxyfluorescein…”
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Murine macrophage phospholipase A2 by Meats, J E, Steele, L

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Effects of lactate on pancreatic islets. Lactate efflux as a possible determinant of islet-cell depolarization by glucose by Best, L, Yates, A P, Meats, J E, Tomlinson, S

“…The secretion of insulin from perifused rat pancreatic islets was stimulated by raising the glucose concentration from 5.6 to 20 mM or by exposure to…”
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Glucose increases cytosolic calcium concentration and inositol lipid metabolism in HIT-T15 cells by Meats, J E, Best, L, Lynch, A M, Tomlinson, S

“…We have investigated the effects of glucose on cytosolic free calcium concentration in the insulin-secreting cell line HIT-T15. Addition of glucose (10 mM)…”
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Modulation of connective tissue metabolism by partially purified human interleukin 1 by Richardson, H J, Elford, P R, Sharrard, R M, Meats, J E, Russell, R G

“…We have investigated the relationship between the monokine interleukin 1 (IL-1) and the connective tissue-stimulating activities produced by monocytes such as…”
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Effects of nutrient and non-nutrient stimuli on cytosolic pH in cultured insulinoma (HIT-T15) cells by Lynch, A M, Meats, J E, Best, L, Tomlinson, S

“…Intracellular pH (pHi) was measured in the insulin-secreting HIT-T15 cell line using the pH-sensitive fluorescent dye,…”
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Lactate alters plasma membrane potential, increases the concentration of cytosolic Ca2+ and stimulates the secretion of insulin by the hamster beta-cell line HIT-T15 by Meats, J E, Tuersley, M D, Best, L, Lynch, A M, Tomlinson, S

“…We have studied the effect of lactate on a number of intracellular events which may be important in controlling the secretion of insulin by the hamster…”
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Identification of phospholipase D (PLD) activity in mouse peritoneal macrophages by Meats, J E, Steele, L, Bowen, J G

“…It is now believed that PLD may contribute to the sustained generation of diacylglycerol (DAG) within activated cells. DAG can be formed from…”
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Partial purification of a factor from human synovium that possesses interleukin 1, chondrocyte stimulating and catabolin-like activities by Elford, Peter R., Meats, Judith E., Sharrard, R.Michael, Russell, R.Graham G.

“…Human synovial explants in culture release material that stimulates the production of prostaglandin E 2 (PGE 2) and several extracellular enzymes by human…”
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Adenylate cyclase of human articular chondrocytes. Responsiveness to prostaglandins and other hormones by Houston, J P, McGuire, M K, Meats, J E, Ebsworth, N M, Russell, R G, Crawford, A, Mac Neil, S

“…Adenylate cyclase [ATP pyrophosphate lyase (cyclizing), EC 4.6.1.1] was shown to be present in cultured human articular chondrocytes. Optimal conditions of…”
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Effects of glucocorticoids and anabolic steroids on cells derived from human skeletal and articular tissues in vitro by Gallagher, J A, Beresford, J N, McGuire, M K, Ebsworth, N M, Meats, J E, Gowen, M, Elford, P, Wright, D, Poser, J, Coulton, L A

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Enhanced production of prostaglandins and plasminogen activator during activation of human articular chondrocytes by products of mononuclear cells by Meats, J E, McGuire, M K, Ebsworth, N M, Englis, D J, Russell, R G

“…We have examined the way in which products of cultured human blood mononuclear cells activate human articular chondrocytes. Conditioned medium from mononuclear…”
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Messenger function of prostaglandins in cell to cell interactions and control of proteinase activity in the rheumatoid joint by McGuire, M K, Meats, J E, Ebsworth, N M, Murphy, G, Reynolds, J J, Russell, R G

“…Destruction of joint structures in arthritis may result from failure of normal mechanisms controlling interactions among cells of the various tissues of the…”
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In vitro activation of human chondrocytes and synoviocytes by a human interleukin-1-like factor by McGuire-Goldring, M B, Meats, J E, Wood, D D, Ihrie, E J, Ebsworth, N M, Russell, R G

“…Monocytes have been shown to secrete factors which stimulate the destruction of cartilage. Since one of the monocyte products, interleukin-1 (IL-1), has been…”
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Retinoids and synovial factor(s) stimulate the production of plasminogen activator by cultured human chondrocytes. A possible role for plasminogen activator in the resorption of cartilage in vitro by Meats, J E, Elford, P R, Bunning, R A, Russell, R G

“…Agents such as retinol, interleukin 1 and catabolin stimulate resorption of cultured cartilage. This process seems to be mediated by chondrocytes, but the…”
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Effects of retinol and dexamethasone on cytokine-mediated control of metalloproteinases and their inhibitors by human articular chondrocytes and synovial cells in culture by McGuire-Goldring, M K, Murphy, G, Gowen, M, Meats, J E, Ebsworth, N M, Poll, C, Reynolds, J J, Russell, R G

“…Human articular chondrocytes in culture produced large amounts of specific mammalian collagenase, gelatinase and proteoglycanase when exposed to dialysed…”
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Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro by Gowen, M, Wood, D D, Ihrie, E J, Meats, J E, Russell, R G

“…Human articular chondrocytes in culture synthesise collagenase and neutral proteoglycanase in response to addition of a 12-17 kDa protein produced by cultured…”
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Properties of rheumatoid and normal synovial tissue in vitro and cells derived from them. Production of prostaglandins and collagenase in response to factors derived from cultured blood mononuclear cells and from synovium by McGuire, M K, Meats, J E, Ebsworth, N M, Harvey, L, Murphy, G, Russell, R G, Reynolds, J J

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Effect of a mononuclear-cell factor on prostaglandin production by cells cultured from human gingiva, synovium, cartilage and endometrium [proceedings] by Englis, D J, D'Souza, S M, Meats, J E, McGuire, M B, Wright, J, Russell, R G

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