Search Results - "Mears, Lisa"

A review of control strategies for manipulating the feed rate in fed-batch fermentation processes by Mears, Lisa, Stocks, Stuart M., Sin, Gürkan, Gernaey, Krist V.

“…•A majority of industrial fermentation processes are operated in fed-batch mode.•The rate of feed addition to the fed-batch process is a focus for optimising…”
Get full text

An Industrial Perspective on Scale-Down Challenges Using Miniaturized Bioreactors by Tajsoleiman, Tannaz, Mears, Lisa, Krühne, Ulrich, Gernaey, Krist V., Cornelissen, Sjef

“…Miniaturized stirred bioreactors (MSBRs) are gaining popularity as a cost-effective approach to scale-down experimentation. However, realizing conditions that…”
Get full text

Application of a mechanistic model as a tool for on‐line monitoring of pilot scale filamentous fungal fermentation processes—The importance of evaporation effects by Mears, Lisa, Stocks, Stuart M., Albaek, Mads O., Sin, Gürkan, Gernaey, Krist V.

“…ABSTRACT A mechanistic model‐based soft sensor is developed and validated for 550L filamentous fungus fermentations operated at Novozymes A/S. The soft sensor…”
Get full text

Locating the stem cell niche and tracing hepatocyte lineages in human liver by Fellous, Tariq G., Islam, Shahriar, Tadrous, Paul J., Elia, George, Kocher, Hemant M., Bhattacharya, Satyajit, Mears, Lisa, Turnbull, Douglas M., Taylor, Robert W., Greaves, Laura C., Chinnery, Patrick F., Taylor, Geoffery, McDonald, Stuart A.C., Wright, Nicholas A., Alison, Malcolm R.

“…We have used immunohistochemical and histochemical techniques to identify patches of hepatocytes deficient in the enzyme cytochrome c oxidase, a component of…”
Get full text

A Methodological Approach to Tracing Cell Lineage in Human Epithelial Tissues by Fellous, Tariq G., McDonald, Stuart A.C., Burkert, Julia, Humphries, Adam, Islam, Shahriar, De‐Alwis, Nemantha M.W., Gutierrez‐Gonzalez, Lydia, Tadrous, Paul J., Elia, George, Kocher, Hemant M., Bhattacharya, Satyajit, Mears, Lisa, El‐Bahrawy, Mona, Turnbull, Douglas M., Taylor, Robert W., Greaves, Laura C., Chinnery, Patrick F., Day, Christopher P., Wright, Nicholas A., Alison, Malcolm R.

“…Methods for lineage tracing of stem cell progeny in human tissues are currently not available. We describe a technique for detecting the expansion of a single…”
Get full text

Lymphoepithelial Cyst of the Pancreas by Arumugam, Prabhu, Fletcher, Natalie, Kyriakides, Charis , Mears, Lisa, Kocher, Hemant M.

“…Lymphoepithelial cyst (LEC) of the pancreas is an extremely rare, benign pancreatic cystic lesion that is difficult to differentiate preoperatively from other…”
Get full text

Repeated Negative Biopsies in Isolated High-Grade Cystic Duct Dysplasia with Progression to Adenocarcinoma by Sunkel-Laing, Benjamin, Kalam, Abdul, Renfrew, Ian, Mears, Lisa, Kocher, Hemant M.

“…Cystic and bile duct dysplasia is a rare histological finding, especially when found in the absence of an underlying malignancy. We report a patient who…”
Get full text

Su1251 CAN CAPSULE SPONGE (CYTOSPONGE/ENDOSIGN) BE INCORPORATED SAFELY INTO BARRETT'S SURVEILLANCE PROGRAMME? RETROSPECTIVE ASSESSMENT OF BARRETT'S DYSPLASIA PATTERNS SPANNING A 6-YEAR DURATION AT A SINGLE SECONDARY CARE SITE by Dimassi, Ahmad, David, Lewis, Shaw, Kim, Mears, Lisa, Morris, Danielle L.

Get full text

Mechanistic Fermentation Models for Process Design, Monitoring, and Control by Mears, Lisa, Stocks, Stuart M., Albaek, Mads O., Sin, Gürkan, Gernaey, Krist V.

“…Mechanistic models require a significant investment of time and resources, but their application to multiple stages of fermentation process development and…”
Get full text

A novel model‐based control strategy for aerobic filamentous fungal fed‐batch fermentation processes by Mears, Lisa, Stocks, Stuart M., Albaek, Mads O., Cassells, Benny, Sin, Gürkan, Gernaey, Krist V.

“…ABSTRACT A novel model‐based control strategy has been developed for filamentous fungal fed‐batch fermentation processes. The system of interest is a pilot…”
Get full text

Challenges in industrial fermentation technology research by Formenti, Luca Riccardo, Nørregaard, Anders, Bolic, Andrijana, Hernandez, Daniela Quintanilla, Hagemann, Timo, Heins, Anna-Lena, Larsson, Hilde, Mears, Lisa, Mauricio-Iglesias, Miguel, Krühne, Ulrich, Gernaey, Krist V.

“…Industrial fermentation processes are increasingly popular, and are considered an important technological asset for reducing our dependence on chemicals and…”
Get full text

Functional unfold principal component regression methodology for analysis of industrial batch process data by Mears, Lisa, Nørregård, Rasmus, Sin, Gürkan, Gernaey, Krist V., Stocks, Stuart M., Albaek, Mads O., Villez, Kris

“…This work proposes a methodology utilizing functional unfold principal component regression (FUPCR), for application to industrial batch process data as a…”
Get full text

Mechanistic Models for Process Development and Optimization of Fed-batch Fermentation Systems by Mears, Lisa, Stocks, Stuart M., Albaek, Mads O., Sin, Gürkan, Gernaey, Krist V.

“…This work discusses the application of mechanistic models to pilot scale filamentous fungal fermentation systems operated at Novozymes A/S. For on-line…”
Get full text

Prevalence of hepatitis C-related cirrhosis in elderly Asian patients infected in childhood by D'Souza, Raymond, Glynn, Michael J, Ushiro-Lumb, Ines, Feakins, Roger, Domizio, Paolo, Mears, Lisa, Alsced, Elspeath, Kumar, Parvar, Sabin, Caroline A, Foster, Graham R

“…Approximately 20% of hepatitis C virus (HCV) patients develop cirrhosis from infection after about 20 years. The proportion of patients developing cirrhosis…”
Get more information

Difference between familial and sporadic medullary thyroid carcinomas by Mears, Lisa, Diaz-Cano, Salvador J

Get full text

Multivariate Analysis of Industrial Scale Fermentation Data by Mears, Lisa, Nørregård, Rasmus, Stocks, Stuart M., Albaek, Mads O., Sin, Gürkan, Gernaey, Krist V., Villez, Kris

“…Multivariate analysis allows process understanding to be gained from the vast and complex datasets recorded from fermentation processes, however the…”
Get full text

Lymphoepithelial Cyst of the Pancreas by Arumugam, Prabhu, Fletcher, Natalie, Kyriakides, Charis, Mears, Lisa, Kocher, Hemant M

Get full text

Repeated negative biopsies in isolated high-grade cystic duct dysplasia with progression to adenocarcinoma by Sunkel-Laing, Benjamin, Kalam, Abdul, Renfrew, Ian, Mears, Lisa, Kocher, Hemant M

Get full text