Search Results - "Meana, Álvaro"
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Polymerizable Skin Hydrogel for Full Thickness Wound Healing
Published in International journal of molecular sciences (27-04-2022)“…The skin is the largest organ in the human body, comprising the main barrier against the environment. When the skin loses its integrity, it is critical to…”
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2
The N125S polymorphism in the cathepsin G gene (rs45567233) is associated with susceptibility to osteomyelitis in a Spanish population
Published in PloS one (24-10-2019)“…Osteomyelitis is a bone infection, most often caused by Staphylococcus aureus, in which neutrophils play a key role. Cathepsin G (CTSG) is a bactericidal…”
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3
In-stent restenosis is associated with proliferative skin healing and specific immune and endothelial cell profiles: results from the RACHEL trial
Published in Frontiers in immunology (31-05-2023)“…In-stent restenosis (ISR) is a major challenge in interventional cardiology. Both ISR and excessive skin healing are aberrant hyperplasic responses, which may…”
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4
Fibrin-Plasma Rich in Growth Factors Membrane for the Treatment of a Rabbit Alkali-Burn Lesion
Published in International journal of molecular sciences (25-05-2021)“…The purpose of this work is to describe the use of Fibrin-Plasma Rich in Growth Factors (PRGF) membranes for the treatment of a rabbit alkali-burn lesion. For…”
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Silk Fibroin Films for Corneal Endothelial Regeneration: Transplant in a Rabbit Descemet Membrane Endothelial Keratoplasty
Published in Investigative ophthalmology & visual science (01-07-2017)“…Develop a silk fibroin (SF)-based artificial endothelial graft for its use in a rabbit Descemet membrane endothelial keratoplasty (DMEK). Human and rabbit…”
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Novel technique of development of human derived acellular dermal matrix
Published in Cell and tissue banking (01-06-2022)“…Reconstructive surgery techniques have evolved exponentially in last decades. From regional flaps to free tissue transfer, tissue movilization has become the…”
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Human Bone Derived Collagen for the Development of an Artificial Corneal Endothelial Graft. In Vivo Results in a Rabbit Model
Published in PloS one (01-12-2016)“…Corneal keratoplasty (penetrating or lamellar) using cadaveric human tissue, is nowadays the main treatment for corneal endotelial dysfunctions. However, there…”
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A Simple, Safe, and Effective Method for Preparing Autologous Bio-Based Fibrin Glue for Ophthalmic Use
Published in Pharmaceutics (28-10-2022)“…This study proposes a method to prepare autologous bio-based fibrin glue (FG) for use in ophthalmic surgery. FGs containing three fibrinogen concentrations and…”
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Unveiling the value of C‐reactive protein as a severity biomarker and the IL4/IL13 pathway as a therapeutic target in recessive dystrophic epidermolysis bullosa: A multiparametric cross‐sectional study
Published in Experimental dermatology (01-08-2024)“…Patients with recessive dystrophic epidermolysis bullosa (RDEB) experience numerous complications, which are exacerbated by inflammatory dysregulation and…”
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Mini Cleanroom for the Manufacture of Advanced Therapy Medicinal Products (ATMP): Bioengineered Corneal Epithelium
Published in Pharmaceutics (17-08-2021)“…Among several requirements for the manufacture of Advanced Therapy Medicinal Products (ATMP) are: following the guidelines of a pharmaceutical quality system,…”
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Isolation of New Stenotrophomonas Bacteriophages and Genomic Characterization of Temperate Phage S1
Published in Applied and Environmental Microbiology (01-12-2008)“…Twenty-two phages that infect Stenotrophomonas species were isolated through sewage enrichment and prophage induction. Of them, S1, S3, and S4 were selected…”
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Ectopic bone formation during tissue-engineered cartilage repair using autologous chondrocytes and novel plasma-derived albumin scaffolds
Published in Journal of cranio-maxillo-facial surgery (01-10-2016)“…Summary Purpose The aims of this study were twofold: first, to evaluate the production of cartilaginous tissue in vitro and in vivo using a novel…”
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13
The regenerative potential of fibroblasts in a new diabetes-induced delayed humanised wound healing model
Published in Experimental dermatology (01-03-2013)“…Cutaneous diabetic wounds greatly affect the quality of life of patients, causing a substantial economic impact on the healthcare system. The limited clinical…”
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Keratinocyte cell lines derived from severe generalized recessive Epidermolysis Bullosa patients carrying a highly recurrent COL7A1 homozygous mutation: models to assess cell and gene therapies in vitro and in vivo
Published in Experimental dermatology (01-09-2013)“…Recessive dystrophic epidermolysis bullosa (RDEB) is caused by deficiency of type VII collagen due to COL7A1 mutations such as c.6527insC, recurrently found in…”
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15
Feeder Layer Cell Actions and Applications
Published in Tissue engineering. Part B, Reviews (01-08-2015)“…Cultures of growth-arrested feeder cells have been used for years to promote cell proliferation, particularly with low-density inocula. Basically, feeder cells…”
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In-house performance assessment of 3D QobuR-Reconstructed Human Cornea-Like Epithelium (RhCE) for the evaluation of eye hazard
Published in Toxicology in vitro (01-08-2022)“…To replace the Draize eye irritation test (OECD Test Guideline 404), several test methods based on reconstructed cornea-like epithelium (RhCE) have been…”
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Regeneration of mandibular osteoradionecrosis with autologous cross-linked serum albumin scaffold
Published in Regenerative medicine (01-07-2020)“…Osteoradionecrosis is one of the most severe complications of radiotherapy administered for head and neck tumors. We present the first two cases of advanced…”
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18
Gels prepared from egg yolk and its fractions for tissue engineering
Published in Biotechnology progress (01-11-2016)“…New biomaterials prepared from egg yolk and its main fractions (plasma and granules) have been developed for use in tissue engineering. Protein gels obtained…”
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Improved Tool for Predicting Skin Irritation on Reconstructed Human Epidermis Models Based on Electrochemical Impedance Spectroscopy
Published in Biosensors (Basel) (20-01-2023)“…The rabbit skin irritation test has been the standard for evaluating the irritation potential of chemicals; however, alternative methods that do not use animal…”
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Development of an in-house reconstructed human epidermis model as an alternative method in skin corrosion assessment
Published in Toxicology in vitro (01-06-2020)“…Defining the corrosive properties of chemical products generally involves the use of animal models for human health safety assessment. However, a few…”
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