Search Results - "Meadows, H."

Chronicle: results of a randomised phase III trial in locally advanced rectal cancer after neoadjuvant chemoradiation randomising postoperative adjuvant capecitabine plus oxaliplatin (XELOX) versus control by Glynne-Jones, R., Counsell, N., Quirke, P., Mortensen, N., Maraveyas, A., Meadows, H.M., Ledermann, J., Sebag-Montefiore, D.

“…In stage III colon cancer, oxaliplatin/5-fluorouracil (5-FU)-based adjuvant chemotherapy (FOLFOX) improves disease-free survival (DFS) and overall survival…”
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Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I) by Northover, J, Glynne-Jones, R, Sebag-Montefiore, D, James, R, Meadows, H, Wan, S, Jitlal, M, Ledermann, J

“…Background: The first UKCCCR Anal Cancer Trial (1996) demonstrated the benefit of chemoradiation over radiotherapy (RT) alone for treating epidermoid anal…”
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Impact of compliance to chemoradiation on long-term outcomes in squamous cell carcinoma of the anus: results of a post hoc analysis from the randomised phase III ACT II trial by Glynne-Jones, R., Meadows, H.M., Lopes, A., Muirhead, R., Sebag-Montefiore, D., Adams, R.

“…Concurrent chemoradiation is standard-of-care for patients with squamous cell carcinoma of the anus. Poor compliance to chemotherapy, radiotherapy treatment…”
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Tumour- and treatment-related colostomy rates following mitomycin C or cisplatin chemoradiation with or without maintenance chemotherapy in squamous cell carcinoma of the anus in the ACT II trial by Glynne-Jones, R., Kadalayil, L., Meadows, H.M., Cunningham, D., Samuel, L., Geh, J.I., Lowdell, C., James, R., Beare, S., Begum, R., Ledermann, J.A., Sebag-Montefiore, D.

“…Squamous cell carcinoma of the anus (SCCA) is highly sensitive to chemoradiation (CRT) which achieves good loco-regional control and preserves anal function…”
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Reply to the letter to the editor: DPD testing in radical chemoradiation for anal squamous cell carcinoma? by R. Muirhead, H. Jones, D. Gilbert, A. Gilbert & C. Jacobs by Glynne-Jones, R., Meadows, H.M., Lopes, A., Muirhead, R., Sebag-Montefiore, D., Adams, R.

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Improving Transplant Patient Safety Through Pharmacist Discharge Medication Reconciliation by Musgrave, C. R., Pilch, N. A., Taber, D. J., Meadows, H. B., McGillicuddy, J. W., Chavin, K. D., Baliga, P. K.

“…Greater than 50% of medication errors are estimated to occur during transitions of care, and solid‐organ transplant recipients are at an increased risk for…”
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Aspirin Sensitivity Wanes Early during Left Ventricular Assist Device Support by Morgan, E.P., Perez, C., Meadows, H., Hawn, J., Fajardo, J., Uber, W., Lozonschi, L., Tedford, R., Houston, B.

“…Aspirin (ASA) therapy is recommended in left ventricular assist device (LVAD) patients to prevent thromboembolic complications. Up to 30% of LVAD patients may…”
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Early Aspirin Therapy May Reduce Hepatic Artery Thrombosis in Liver Transplantation by Shay, R, Taber, D, Pilch, N, Meadows, H, Tischer, S, McGillicuddy, J, Bratton, C, Baliga, P, Chavin, K

“…Abstract Background Hepatic artery thrombosis (HAT) remains among the leading causes of early graft loss after liver transplantation. Our transplant center…”
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A phase I II study of irinotecan when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group Study by GLYNNE-JONES, R, FALK, S, MAUGHAN, T. S, MEADOWS, H. M, SEBAG-MONTEFIORE, D

“…The objective of this study was to evaluate the maximum tolerated dose (MTD) and recommended dose of irinotecan administered as a 5-day schedule synchronously…”
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A phase I II study of oxaliplatin when added to 5-fluorouracil and leucovorin and pelvic radiation in locally advanced rectal cancer: a Colorectal Clinical Oncology Group (CCOG) study by SEBAG-MONTEFIORE, D, GLYNNE-JONES, R, FALK, S, MEADOWS, H. M, MAUGHAN, T

“…The purpose of this study was to evaluate the maximum tolerated dose (MTD) and recommended dose of oxaliplatin given synchronously with 5-fluorouracil (5FU),…”
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Prediction of medication non-adherence and associated outcomes in pediatric kidney transplant recipients by Connelly, James, Pilch, N., Oliver, M., Jordan, C., Fleming, J., Meadows, H., Baliga, P., Nadig, S., Twombley, K., Shatat, I., Taber, D.

“…Studies have continued to evaluate risk factors associated with post‐transplant non‐adherence in pediatric patients. However, many of these studies fail to…”
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Impact of Angiotensin II Inhibitors on the Incidence of Gastrointestinal Bleeds After Left Ventricular Assist Device Placement by Converse, M, Sobhanian, M, Mardis, A, Taber, D, Uber, W, Meadows, H, Houston, B, Patel, N, Vanbakel, A

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The Impact of Pre-LVAD Psychosocial Evaluations on Post-LVAD Outcomes by Sobhanian, M, Converse, M, Patel, N, Mardis, A, Taber, D, Houston, B, Ramu, B, Serber, E, Agyemang, A, Heyward, D, Uber, W, Meadows, H

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Suppressive Antibiotics for LVAD-Associated Infections: Are They Helpful or Harmful? by Strout, S, Veasey, T, Rieger, K, Floroff, C, Wray, D, Brisco, M, Cook, J, Craig, M, Toole, J, Van Bakel, A, Heyward, D, Uber, W, Meadows, H

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Evaluation of Anticoagulation and Non-Surgical Major Bleeding in Recipients of Continuous-Flow Left Ventricular Assist Devices by Veasey, T, Strout, S, Rieger, K, Floroff, C, Brisco, M, Cook, J, Toole, J, Craig, M, VanBakel, A, Heyward, D, Uber, W, Meadows, H

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Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS by Hervieu, G.J, Cluderay, J.E, Gray, C.W, Green, P.J, Ranson, J.L, Randall, A.D, Meadows, H.J

“…TREK-1 is a member of the two-pore-domain potassium channel family which is expressed predominantly in the CNS. Using an anti-peptide polyclonal antiserum, we…”
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Functional characterisation of human TASK-3, an acid-sensitive two-pore domain potassium channel by Meadows, H.J., Randall, A.D.

“…Human TASK-3 (hTASK-3) is a recently identified member of the two-pore domain potassium channel (2PDKC) family which in man is predominantly expressed in the…”
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In vivo gastrocnemius muscle fascicle length in children with and without diplegic cerebral palsy by Mohagheghi, AA, Khan, T, Meadows, TH, Giannikas, K, Baltzopoulos, V, Maganaris, CN

“…The effect of spastic cerebral palsy on in vivo gastrocnemius muscle fascicle length is not clear. Similarity of fascicle lengths in children with diplegia and…”
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Effects of pulsed laser annealing on deep level defects in electrochemically-deposited and furnace annealed CuInSe2 thin films by Bhatia, A., Meadows, H., Hlaing Oo, W.M., Dale, P.J., Scarpulla, M.A.

“…CuInSe2 (CISe) is a prototype material for the I–III–VI chalcopyrites such as Cu(In,Ga)(S,Se)2 used as absorber layers in thin film photovoltaic cells…”
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Acute hypoxia occludes hTREK-1 modulation: re-evaluation of the potential role of tandem P domain K+ channels in central neuroprotection by Miller, P, Kemp, P J, Lewis, A, Chapman, C G, Meadows, H J, Peers, C

“…The human tandem P domain K + channel hTREK-1 (KCNK2) is distributed widely through the CNS. Here, whole-cell patch clamp recordings were employed to…”
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