Search Results - "Meade, Aidan D."

Discrimination of breast cancer from benign tumours using Raman spectroscopy by Lyng, Fiona M, Traynor, Damien, Nguyen, Thi Nguyet Que, Meade, Aidan D, Rakib, Fazle, Al-Saady, Rafif, Goormaghtigh, Erik, Al-Saad, Khalid, Ali, Mohamed H

“…Breast cancer is the most common cancer among women worldwide, with an estimated 1.7 million cases and 522,000 deaths in 2012. Breast cancer is diagnosed by…”
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Discrimination of immune cell activation using Raman micro-spectroscopy in an in-vitro & ex-vivo model by Chaudhary, Neha, Nguyen, Thi Nguyet Que, Cullen, Daniel, Meade, Aidan D., Wynne, Claire

“…[Display omitted] •Raman spectroscopy is an effective method for the differentiation of immune cells.•Cell lines and primary cells in both resting and…”
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Phenotypic and Functional Characteristics of Exosomes Derived from Irradiated Mouse Organs and Their Role in the Mechanisms Driving Non-Targeted Effects by Tuncay Cagatay, Seda, Mayah, Ammar, Mancuso, Mariateresa, Giardullo, Paola, Pazzaglia, Simonetta, Saran, Anna, Daniel, Amuthachelvi, Traynor, Damien, Meade, Aidan D, Lyng, Fiona, Tapio, Soile, Kadhim, Munira

“…Molecular communication between irradiated and unirradiated neighbouring cells initiates radiation-induced bystander effects (RIBE) and out-of-field (abscopal)…”
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Development of a high throughput (HT) Raman spectroscopy method for rapid screening of liquid blood plasma from prostate cancer patients by Medipally, Dinesh K R, Maguire, Adrian, Bryant, Jane, Armstrong, John, Dunne, Mary, Finn, Marie, Lyng, Fiona M, Meade, Aidan D

“…Extensive research has been undertaken on the examination of tissue biopsies using vibrational spectroscopic techniques. However, fewer studies have focused on…”
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Application of Advanced Non-Linear Spectral Decomposition and Regression Methods for Spectroscopic Analysis of Targeted and Non-Targeted Irradiation Effects in an In-Vitro Model by Slattery, Ciara, Nguyen, Khanh, Shields, Laura, Vega-Carrascal, Isabel, Singleton, Sean, Lyng, Fiona M., McClean, Brendan, Meade, Aidan D.

“…Irradiation of the tumour site during treatment for cancer with external-beam ionising radiation results in a complex and dynamic series of effects in both the…”
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Studies of chemical fixation effects in human cell lines using Raman microspectroscopy by Meade, Aidan D, Clarke, Colin, Draux, Florence, Sockalingum, Ganesh D, Manfait, Michel, Lyng, Fiona M, Byrne, Hugh J

“…The in vitro study of cellular species using Raman spectroscopy has proven a powerful non-invasive modality for the analysis of cell constituents and…”
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Radiobiological Applications of Vibrational Spectroscopy: A Review of Analyses of Ionising Radiation Effects in Biology and Medicine by Monaghan, Jade F., Byrne, Hugh J., Lyng, Fiona M., Meade, Aidan D.

“…Vibrational spectroscopic techniques, such as Fourier transform infrared (FTIR) absorption and Raman spectroscopy (RS), offer unique and detailed biochemical…”
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Out-of-Field Hippocampus from Partial-Body Irradiated Mice Displays Changes in Multi-Omics Profile and Defects in Neurogenesis by Pazzaglia, Simonetta, Tanno, Barbara, Antonelli, Francesca, Giardullo, Paola, Babini, Gabriele, Subedi, Prabal, Azimzadeh, Omid, Khan, Zohaib N, Oleksenko, Kateryna, Metzger, Fabian, Toerne, Christine von, Traynor, Damien, Medipally, Dinesh, Meade, Aidan D, Kadhim, Munira, Lyng, Fiona M, Tapio, Soile, Saran, Anna, Mancuso, Mariateresa

“…The brain undergoes ionizing radiation exposure in many clinical situations, particularly during radiotherapy for brain tumors. The critical role of the…”
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Correction: Discrimination of breast cancer from benign tumours using Raman spectroscopy by Lyng, Fiona M, Traynor, Damien, Nguyen, Thi Nguyet Que, Meade, Aidan D, Rakib, Fazle, Al-Saady, Rafif, Goormaghtigh, Erik, Al-Saad, Khalid, Ali, Mohamed H

“…[This corrects the article DOI: 10.1371/journal.pone.0212376.]…”
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Raman spectroscopy for the preoperative diagnosis of thyroid cancer and its subtypes: An in vitro proof‐of‐concept study by O'Dea, Declan, Bongiovanni, Massimo, Sykiotis, Gerasimos P., Ziros, Panos G., Meade, Aidan D., Lyng, Fiona M., Malkin, Alison

“…Objective In 2016, there were an estimated 56 870 new cases of thyroid cancer (TC) in the USA. Fine needle aspiration cytology (FNAC) is the most safe,…”
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Vibrational spectroscopy of liquid biopsies for prostate cancer diagnosis by Medipally, Dinesh K. R., Cullen, Daniel, Untereiner, Valérie, Sockalingum, Ganesh D., Maguire, Adrian, Nguyen, Thi Nguyet Que, Bryant, Jane, Noone, Emma, Bradshaw, Shirley, Finn, Marie, Dunne, Mary, Shannon, Aoife M., Armstrong, John, Meade, Aidan D., Lyng, Fiona M

“…Background: Screening for prostate cancer with prostate specific antigen and digital rectal examination allows early diagnosis of prostate malignancy but has…”
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Growth substrate induced functional changes elucidated by FTIR and Raman spectroscopy in in-vitro cultured human keratinocytes by Meade, Aidan D, Lyng, Fiona M, Knief, Peter, Byrne, Hugh J

“…Non-invasive measurements of cellular function in in vitro cultured cell lines using vibrational spectroscopy require the use of spectroscopic substrates such…”
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Quantitative reagent-free detection of fibrinogen levels in human blood plasma using Raman spectroscopy by Poon, Kelvin W C, Lyng, Fiona M, Knief, Peter, Howe, Orla, Meade, Aidan D, Curtin, James F, Byrne, Hugh J, Vaughan, Joe

“…Fibrinogen assays are commonly used as part of clinical screening tests to investigate haemorrhagic states, for detection of disseminated intravascular…”
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Chemical imaging and machine learning for sub‐classification of oesophageal tissue histology by Keogan, Abigail, Nguyen, Thi Nguyet Que, Phelan, James J., O'Farrell, Naoimh, Lynam‐Lennon, Niamh, Doyle, Brendan, O'Toole, Dermot, Reynolds, John V., O'Sullivan, Jacintha, Meade, Aidan D.

“…Fourier Transform Infrared (FTIR) based chemical imaging is a powerful, non‐destructive and label‐free biophotonic technique, which spatially acquires…”
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Prediction of pathological response to neo‐adjuvant chemoradiotherapy for oesophageal cancer using vibrational spectroscopy by Nguyen, Thi N. Q., Maguire, Adrian, Mooney, Catherine, Jackson, Naomi, Lynam‐Lennon, Niamh, Weldon, Vicki, Muldoon, Cian, Maguire, Aoife A., O'Toole, D., Ravi, Narayanasamy, Reynolds, John V., O'Sullivan, Jacintha, Meade, Aidan D.

“…In oesophageal cancer (OC) neo‐adjuvant chemoradiotherapy (neoCRT) is used to debulk tumour size prior to surgery, with a complete pathological response (pCR)…”
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MicroRNA Analysis of ATM-Deficient Cells Indicate PTEN and CCDN1 as Potential Biomarkers of Radiation Response by Bryant, Jane, White, Lisa, Coen, Natasha, Shields, Laura, McClean, Brendan, Meade, Aidan D., Lyng, Fiona M., Howe, Orla

“…Genetic and epigenetic profile changes associated with individual radiation sensitivity are well documented and have led to enhanced understanding of the…”
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Vibrational spectroscopy in sensing radiobiological effects: analyses of targeted and non-targeted effects in human keratinocytes by Meade, Aidan D, Howe, Orla, Unterreiner, Valérie, Sockalingum, Ganesh D, Byrne, Hugh J, Lyng, Fiona M

“…Modern models of radiobiological effects include mechanisms of damage initiation, sensing and repair, for those cells that directly absorb ionizing radiation…”
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Comparison of sample preparation methodologies towards optimisation of Raman spectroscopy for peripheral blood mononuclear cells by Chaudhary, Neha, Que Nguyen, Thi Nguyet, Maguire, Adrian, Wynne, Claire, Meade, Aidan D

“…The exquisite sensitivity of Raman spectroscopy to the molecular composition of biological samples has been a particular strength in its development towards…”
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Raman micro spectroscopy study of the interaction of vincristine with A549 cells supported by expression analysis of bcl-2 protein by Nawaz, Haq, Garcia, Amaya, Meade, Aidan D, Lyng, Fiona M, Byrne, Hugh J

“…Understanding the interaction of anticancer drugs with model cell lines is important to elucidate the mode of action of these drugs as well as to develop cost…”
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Evaluation of the potential of Raman microspectroscopy for prediction of chemotherapeutic response to cisplatin in lung adenocarcinoma by Nawaz, Haq, Bonnier, Franck, Knief, Peter, Howe, Orla, Lyng, Fiona M, Meade, Aidan D, Byrne, Hugh J

“…The study of the interaction of anticancer drugs with mammalian cells in vitro is important to elucidate the mechanisms of action of the drug on its biological…”
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