Search Results - "Mead, Scott"

Precision Medicine for Advanced Pancreas Cancer: The Individualized Molecular Pancreatic Cancer Therapy (IMPaCT) Trial by Chantrill, Lorraine A, Nagrial, Adnan M, Watson, Clare, Johns, Amber L, Martyn-Smith, Mona, Simpson, Skye, Mead, Scott, Jones, Marc D, Samra, Jaswinder S, Gill, Anthony J, Watson, Nicole, Chin, Venessa T, Humphris, Jeremy L, Chou, Angela, Brown, Belinda, Morey, Adrienne, Pajic, Marina, Grimmond, Sean M, Chang, David K, Thomas, David, Sebastian, Lucille, Sjoquist, Katrin, Yip, Sonia, Pavlakis, Nick, Asghari, Ray, Harvey, Sandra, Grimison, Peter, Simes, John, Biankin, Andrew V

“…Personalized medicine strategies using genomic profiling are particularly pertinent for pancreas cancer. The Individualized Molecular Pancreatic Cancer Therapy…”
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Clinical and Pathologic Features of Familial Pancreatic Cancer by HUMPHRIS, Jeremy L, JOHNS, Amber L, SCOTT MEAD, R, GILL, Anthony J, SAMRA, Jaswinder S, KENCH, James G, MUSGROVE, Elizabeth A, TUCKER, Katherine M, SPIGELMAN, Allan D, WADDELL, Nic, GRIMMOND, Sean M, BIANKIN, Andrew V, SIMPSON, Skye H, COWLEY, Mark J, PAJIC, Marina, CHANG, David K, NAGRIAL, Adnan M, CHIN, Venessa T, CHANTRILL, Lorraine A, PINESE, Mark

“…Inherited predisposition to pancreatic cancer contributes significantly to its incidence and presents an opportunity for the development of early detection…”
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BRAFV600E Immunohistochemistry Facilitates Universal Screening of Colorectal Cancers for Lynch Syndrome by Toon, Christopher W., Walsh, Michael D., Chou, Angela, Capper, David, Clarkson, Adele, Sioson, Loretta, Clarke, Stephen, Mead, Scott, Walters, Rhiannon J., Clendenning, Mark, Rosty, Christophe, Young, Joanne P., Win, Aung Ko, Hopper, John L., Crook, Ashley, von Deimling, Andreas, Jenkins, Mark A., Buchanan, Daniel D., Gill, Anthony J.

“…BRAFV600E mutation in microsatellite-unstable (MSI) colorectal carcinomas (CRCs) virtually excludes Lynch syndrome (LS). In microsatellite-stable (MSS) CRCs it…”
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Germline deletion of ETV6 in familial acute lymphoblastic leukemia by Rampersaud, Evadnie, Ziegler, David S., Iacobucci, Ilaria, Payne-Turner, Debbie, Churchman, Michelle L., Schrader, Kasmintan A., Joseph, Vijai, Offit, Kenneth, Tucker, Katherine, Sutton, Rosemary, Warby, Meera, Chenevix-Trench, Georgia, Huntsman, David G., Tsoli, Maria, Mead, R. Scott, Qu, Chunxu, Leventaki, Vasiliki, Wu, Gang, Mullighan, Charles G.

“…Recent studies have identified germline mutations in TP53, PAX5, ETV6, and IKZF1 in kindreds with familial acute lymphoblastic leukemia (ALL), but the genetic…”
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Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes by Biankin, Andrew V., Waddell, Nicola, Kassahn, Karin S., Gingras, Marie-Claude, Miller, David K., Wilson, Peter J., Patch, Ann-Marie, Cowley, Mark J., Gardiner, Brooke B., Idrisoglu, Senel, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Wani, Shivangi, Gongora, Milena, Pajic, Marina, Gill, Anthony J., Pinho, Andreia V., Holmes, Oliver, Leonard, Conrad, Taylor, Darrin, Xu, Qinying, Nones, Katia, Lynn Fink, J., Christ, Angelika, Bruxner, Tim, Cloonan, Nicole, Kolle, Gabriel, Newell, Felicity, Pinese, Mark, Humphris, Jeremy L., Kaplan, Warren, Jones, Marc D., Colvin, Emily K., Nagrial, Adnan M., Humphrey, Emily S., Chou, Angela, Chantrill, Lorraine A., Kench, James G., Lovell, Jessica A., Daly, Roger J., Merrett, Neil D., Toon, Christopher, Epari, Krishna, Nguyen, Nam Q., Barbour, Andrew, Zeps, Nikolajs, Kakkar, Nipun, Zhao, Fengmei, Qing Wu, Yuan, Muzny, Donna M., Fisher, William E., Charles Brunicardi, F., Hodges, Sally E., Reid, Jeffrey G., Drummond, Jennifer, Chang, Kyle, Han, Yi, Lewis, Lora R., Dinh, Huyen, Buhay, Christian J., Timms, Lee, Begley, Kimberly, Brown, Andrew, Pai, Deepa, Panchal, Ami, Buchner, Nicholas, Denroche, Robert E., Yung, Christina K., Serra, Stefano, Onetto, Nicole, Mukhopadhyay, Debabrata, Tsao, Ming-Sound, Shaw, Patricia A., Gallinger, Steven, Hruban, Ralph H., Maitra, Anirban, Iacobuzio-Donahue, Christine A., Schulick, Richard D., Morgan, Richard A., Lawlor, Rita T., Scardoni, Maria, Tortora, Giampaolo, Tempero, Margaret A., Mann, Karen M., Jenkins, Nancy A., Perez-Mancera, Pedro A., Adams, David J., Wessels, Lodewyk F. A., Rust, Alistair G., Stein, Lincoln D., Tuveson, David A., Musgrove, Elizabeth A., Hudson, Thomas J., Sutherland, Robert L., Wheeler, David A., Pearson, John V., McPherson, John D., Gibbs, Richard A., Grimmond, Sean M.

“…Pancreatic cancer is a highly lethal malignancy with few effective therapies. We performed exome sequencing and copy number analysis to define genomic…”
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Clinical and molecular characterization of HER2 amplified-pancreatic cancer by Chou, Angela, Waddell, Nicola, Cowley, Mark J, Gill, Anthony J, Chang, David K, Patch, Ann-Marie, Nones, Katia, Wu, Jianmin, Pinese, Mark, Johns, Amber L, Miller, David K, Kassahn, Karin S, Nagrial, Adnan M, Wasan, Harpreet, Goldstein, David, Toon, Christopher W, Chin, Venessa, Chantrill, Lorraine, Humphris, Jeremy, Mead, R Scott, Rooman, Ilse, Samra, Jaswinder S, Pajic, Marina, Musgrove, Elizabeth A, Pearson, John V, Morey, Adrienne L, Grimmond, Sean M, Biankin, Andrew V

“…Pancreatic cancer is one of the most lethal and molecularly diverse malignancies. Repurposing of therapeutics that target specific molecular mechanisms in…”
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Exploring Racial Differences in Disease Prevalence in a Preclinical Curriculum by Flynn, Maxfield P., Altschafl, Beth, Mead, Scott, Cowan, Eileen, Ranheim, Erik, Cotter, Meghan, Pelley, Elaine

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Zebrafish runx1 promoter-EGFP transgenics mark discrete sites of definitive blood progenitors by Yi Ni Lam, Enid, Chau, Jackie Y.M., Kalev-Zylinska, Maggie L., Fountaine, Timothy M., Mead, R. Scott, Hall, Christopher J., Crosier, Philip S., Crosier, Kathryn E., Vega Flores, Maria

“…The transcription factor Runx1 is essential for the development of definitive hematopoietic stem cells (HSCs) during vertebrate embryogenesis and is…”
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Medical Students as Educators: Students' Experience, Interest, and Confidence in Teaching by Cha, Leah, Buzzard, Lydia, Jasicki, Mallory, Mirrielees, Jennifer, Broman, Aimee T, Mead, Scott

“…Medical students represent the next generation of physician educators, yet may not be prepared to meet future teaching responsibilities. An electronic survey…”
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EGFR mutation profile in Australian patients with non-small cell lung cancer by Mead, Scott, Lucas, Mark, Pang, Jia-Min, Fellowes, Andrew, Harraway, James, Svobodova, Suzanne, Amanuel, Benhur, Fox, Stephen

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Sudden Cardiac Death Due to Deficiency of the Mitochondrial Inorganic Pyrophosphatase PPA2 by Kennedy, Hannah, Haack, Tobias B., Hartill, Verity, Mataković, Lavinija, Baumgartner, E. Regula, Potter, Howard, Mackay, Richard, Alston, Charlotte L., O’Sullivan, Siobhan, McFarland, Robert, Connolly, Grainne, Gannon, Caroline, King, Richard, Mead, Scott, Crozier, Ian, Chan, Wandy, Florkowski, Chris M., Sage, Martin, Höfken, Thomas, Alhaddad, Bader, Kremer, Laura S., Kopajtich, Robert, Feichtinger, René G., Sperl, Wolfgang, Rodenburg, Richard J., Minet, Jean Claude, Dobbie, Angus, Strom, Tim M., Meitinger, Thomas, George, Peter M., Johnson, Colin A., Taylor, Robert W., Prokisch, Holger, Doudney, Kit, Mayr, Johannes A.

“…We have used whole-exome sequencing in ten individuals from four unrelated pedigrees to identify biallelic missense mutations in the nuclear-encoded…”
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Abstract LB-138: Zero Childhood Cancer: A comprehensive precision medicine platform for children with high-risk cancer by Mould, Emily, Lau, Loretta, Arndt, Greg, Barahona, Paulette, Cowley, Mark, Ekert, Paul, Failes, Tim, Fletcher, Jamie, Gifford, Andrew, Haber, Michelle, Kamili, Alvin, Kumar, Amit, Lock, Richard, Marshall, Glenn, Mayoh, Chelsea, Mead, Scott, Norris, Murray, O'Brien, Tracey, Pinese, Mark, Quang, Dong Anh Khuong, Trahair, Toby, Tsoli, Maria, Tucker, Katherine, Warby, Meera, Wong, Marie, Xie, Jinhan, Ziegler, David, Tyrrell, Vanessa

“…Abstract Molecular genomics analyses aim to identify the subset of patients harbouring actionable mutations as a pathway to better targeted treatment…”
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Infection Control Knowledge, Attitudes, and Practices among Healthcare Workers at Mulago Hospital, Kampala, Uganda by Sethi, Ajay K., Acher, Charles W., Kirenga, Bruce, Mead, Scott, Donskey, Curtis J., Katamba, Achilles

“…Objective. Effective implementation of infection control programs and adherence to standard precautions are challenging in resource-limited settings. The…”
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Towards a test to predict 5-fluorouracil toxicity: Pharmacokinetic data for thymine and two sequential metabolites following oral thymine administration to healthy adult males by Duley, John A., Ni, Ming, Shannon, Catherine, Norris, Ross L., Sheffield, Lesley, Harris, Marion, van Kuilenburg, Andre B.P., Mead, Scott, Cameron, Andrew, Helsby, Nuala, George, Rani, Charles, Bruce G.

“…The fluoropyrimidine drugs 5-fluorouracil and its oral prodrug capecitabine remain first line therapy for solid tumours of the neck, breast and colon. However,…”
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RCPA standards for clinical databases of genetic variants by Bennetts, Bruce, Caramins, Melody, Hsu, Arthur, Lau, Chiyan, Scott Mead, R., Meldrum, Cliff, Suthers, Graeme, Taylor, Graham, Tyrrell, Vanessa

“…It is routine practice to compare sequence variations identified during clinical genetic testing with variants recorded in a wide range of databases and…”
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Zero childhood cancer – Accelerating translation of experimental oncology: Better matching drug to target by Tyrrell, Vanessa, Lau, Loretta, Arndt, Greg, Barahona, Paulette, Cowley, Mark, Ekert, Paul, Failes, Tim, Fletcher, Jamie, Gifford, Andrew, Haber, Michelle, Kamili, Alvin, Kumar, Amit, Lock, Richard, Marshall, Glenn, Mayoh, Chelsea, Mead, Scott, Mould, Emily, O'Brien, Tracey, Pinese, Mark, Khuong-Quang, Dong Anh, Thomas, David, Trahair, Toby, Tsoli, Maria, Tucker, Kathryn, Wharby, Meera, Wong, Marie, Xie, Jinhan, Ziegler, David

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Differential identification of a rare form of platelet‐type (pseudo‐) von Willebrand disease (VWD) from Type 2B VWD using a simplified ristocetin‐induced‐platelet‐agglutination mixing assay and confirmed by genetic analysis by Favaloro, Emmanuel J., Patterson, David, Denholm, Anna, Mead, Scott, Gilbert, Ann, Collins, Anne, Estell, Jane, George, Peter M., Smith, Mark P.

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Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer by Balachandran, Vinod P., Łuksza, Marta, Zhao, Julia N., Makarov, Vladimir, Moral, John Alec, Remark, Romain, Herbst, Brian, Askan, Gokce, Bhanot, Umesh, Senbabaoglu, Yasin, Wells, Daniel K., Cary, Charles Ian Ormsby, Grbovic-Huezo, Olivera, Attiyeh, Marc, Medina, Benjamin, Zhang, Jennifer, Loo, Jennifer, Saglimbeni, Joseph, Abu-Akeel, Mohsen, Zappasodi, Roberta, Riaz, Nadeem, Smoragiewicz, Martin, Kelley, Z. Larkin, Basturk, Olca, Gönen, Mithat, Levine, Arnold J., Allen, Peter J., Fearon, Douglas T., Merad, Miriam, Gnjatic, Sacha, Iacobuzio-Donahue, Christine A., Wolchok, Jedd D., DeMatteo, Ronald P., Chan, Timothy A., Greenbaum, Benjamin D., Merghoub, Taha, Leach, Steven D.

“…The analysis of T-cell antigens in long-term survivors of pancreatic ductal adenocarcinoma suggests that neoantigen immunogenicity and quality, not purely…”
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Feasibility of an evidence-based medicine educational prescription by Feldstein, David A, Mead, Scott, Manwell, Linda B

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EGFR mutation specific immunohistochemistry is a useful adjunct which helps to identify false negative mutation testing in lung cancer by Houang, Michelle, Sioson, Loretta, Clarkson, Adele, Watson, Nicole, Farzin, Mahtab, Toon, Christopher W., Raut, Aditi, O’Toole, Sandra A., Cooper, Wendy A., Pavlakis, Nick, Mead, Scott, Chou, Angela, Gill, Anthony J.

“…Mutations in EGFR guide treatment in non-small cell lung cancer (NSCLC). The most common mutations, exon 19 (delE746-A750) and exon 21 (L858R), can be…”
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