Search Results - "Meaburn, Emma"

Estimation of a significance threshold for epigenome‐wide association studies by Saffari, Ayden, Silver, Matt J., Zavattari, Patrizia, Moi, Loredana, Columbano, Amedeo, Meaburn, Emma L., Dudbridge, Frank

“…ABSTRACT Epigenome‐wide association studies (EWAS) are designed to characterise population‐level epigenetic differences across the genome and link them to…”
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Evidence for specificity of polygenic contributions to attainment in English, maths and science during adolescence by Donati, Georgina, Dumontheil, Iroise, Pain, Oliver, Asbury, Kathryn, Meaburn, Emma L.

“…How well one does at school is predictive of a wide range of important cognitive, socioeconomic, and health outcomes. The last few years have shown marked…”
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Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? by Sieradzka, Dominika, Power, Robert A, Freeman, Daniel, Cardno, Alastair G, McGuire, Philip, Plomin, Robert, Meaburn, Emma L, Dudbridge, Frank, Ronald, Angelica

“…Psychosis has been hypothesised to be a continuously distributed quantitative phenotype and disorders such as schizophrenia and bipolar disorder represent its…”
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Allelic Skewing of DNA Methylation Is Widespread across the Genome by Schalkwyk, Leonard C., Meaburn, Emma L., Smith, Rebecca, Dempster, Emma L., Jeffries, Aaron R., Davies, Matthew N., Plomin, Robert, Mill, Jonathan

“…DNA methylation is assumed to be complementary on both alleles across the genome, although there are exceptions, notably in regions subject to genomic…”
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Genome‐Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education by Donati, Georgina, Dumontheil, Iroise, Meaburn, Emma L.

“…ABSTRACT Individual differences in executive functions (EF) are heritable and predictive of academic attainment (AA). However, little is known about genetic…”
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Allele-specific methylation in the human genome: Implications for genetic studies of complex disease by Meaburn, Emma L., Schalkwyk, Leonard C., Mill, Jonathan

“…Across the genome, outside of a small number of known imprinted genes and regions subject to X-inactivation in females, DNA methylation at CpG dinucleotides is…”
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First genome-wide association study on anxiety-related behaviours in childhood by Trzaskowski, Maciej, Eley, Thalia C, Davis, Oliver S P, Doherty, Sophia J, Hanscombe, Ken B, Meaburn, Emma L, Haworth, Claire M A, Price, Thomas, Plomin, Robert

“…Twin studies have shown that anxiety in a general population sample of children involves both domain-general and trait-specific genetic effects. For this…”
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Association of Polygenic Liability for Autism With Face-Sensitive Cortical Responses From Infancy by Gui, Anna, Meaburn, Emma L, Tye, Charlotte, Charman, Tony, Johnson, Mark H, Jones, Emily J H

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Common DNA Markers Can Account for More Than Half of the Genetic Influence on Cognitive Abilities by Plomin, Robert, Haworth, Claire M. A., Meaburn, Emma L., Price, Thomas S., Davis, Oliver S. P.

“…For nearly a century, twin and adoption studies have yielded substantial estimates of heritability for cognitive abilities, although it has proved difficult…”
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Genetics of callous-unemotional behavior in children by Viding, Essi, Price, Thomas S, Jaffee, Sara R, Trzaskowski, Maciej, Davis, Oliver S P, Meaburn, Emma L, Haworth, Claire M A, Plomin, Robert

“…Callous-unemotional behavior (CU) is currently under consideration as a subtyping index for conduct disorder diagnosis. Twin studies routinely estimate the…”
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Increasing Heritability of BMI and Stronger Associations With the FTO Gene Over Childhood by Haworth, Claire M.A., Carnell, Susan, Meaburn, Emma L., Davis, Oliver S.P., Plomin, Robert, Wardle, Jane

“…The growing evidence of health risks associated with the rise in childhood obesity adds to the urgency of understanding the determinants of BMI. Twin analyses…”
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RNA sequencing of identical twins discordant for autism reveals blood-based signatures implicating immune and transcriptional dysregulation by Saffari, Ayden, Arno, Matt, Nasser, Eric, Ronald, Angelica, Wong, Chloe C Y, Schalkwyk, Leonard C, Mill, Jonathan, Dudbridge, Frank, Meaburn, Emma L

“…A gap exists in our mechanistic understanding of how genetic and environmental risk factors converge at the molecular level to result in the emergence of…”
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Common variation near ROBO2 is associated with expressive vocabulary in infancy by St Pourcain, Beate, Cents, Rolieke A.M., Whitehouse, Andrew J.O., Haworth, Claire M.A., Davis, Oliver S.P., O’Reilly, Paul F., Roulstone, Susan, Wren, Yvonne, Ang, Qi W., Velders, Fleur P., Evans, David M., Kemp, John P., Warrington, Nicole M., Miller, Laura, Timpson, Nicholas J., Ring, Susan M., Verhulst, Frank C., Hofman, Albert, Rivadeneira, Fernando, Meaburn, Emma L., Price, Thomas S., Dale, Philip S., Pillas, Demetris, Yliherva, Anneli, Rodriguez, Alina, Golding, Jean, Jaddoe, Vincent W.V., Jarvelin, Marjo-Riitta, Plomin, Robert, Pennell, Craig E., Tiemeier, Henning, Davey Smith, George

“…Twin studies suggest that expressive vocabulary at ~24 months is modestly heritable. However, the genes influencing this early linguistic phenotype are…”
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In search of genes associated with risk for psychopathic tendencies in children: a two-stage genome-wide association study of pooled DNA by Viding, Essi, Hanscombe, Ken B., Curtis, Charles J.C., Davis, Oliver S.P., Meaburn, Emma L., Plomin, Robert

“…Background:  Quantitative genetic data from our group indicates that antisocial behaviour (AB) is strongly heritable when coupled with psychopathic,…”
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Tissue-specific patterns of allelically-skewed DNA methylation by Marzi, Sarah J., Meaburn, Emma L., Dempster, Emma L., Lunnon, Katie, Paya-Cano, Jose L., Smith, Rebecca G., Volta, Manuela, Troakes, Claire, Schalkwyk, Leonard C., Mill, Jonathan

“…While DNA methylation is usually thought to be symmetrical across both alleles, there are some notable exceptions. Genomic imprinting and X chromosome…”
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A Three-Stage Genome-Wide Association Study of General Cognitive Ability: Hunting the Small Effects by Davis, Oliver S. P., Butcher, Lee M., Docherty, Sophia J., Meaburn, Emma L., Curtis, Charles J. C., Simpson, Michael A., Schalkwyk, Leonard C., Plomin, Robert

“…Childhood general cognitive ability ( g ) is important for a wide range of outcomes in later life, from school achievement to occupational success and life…”
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Genome-Wide Association Study of Receptive Language Ability of 12-Year-Olds by Harlaar, Nicole, Meaburn, Emma L, Hayiou-Thomas, Marianna E, Davis, Oliver S. P, Docherty, Sophia, Hanscombe, Ken B, Haworth, Claire M. A, Price, Thomas S, Trzaskowski, Maciej, Dale, Philip S, Plomin, Robert

“…Purpose: Researchers have previously shown that individual differences in measures of receptive language ability at age 12 are highly heritable. In the current…”
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Correction: First Genome-Wide Association Study on Anxiety-Related Behaviours in Childhood by Trzaskowski, Maciej, Eley, Thalia C., Davis, Oliver S. P., Doherty, Sophia J., Hanscombe, Ken B., Meaburn, Emma L., Haworth, Claire M. A., Price, Thomas, Plomin, Robert

“…(2013) First Genome-Wide Association Study on Anxiety-Related Behaviours in Childhood. (2013) Correction: First Genome-Wide Association Study on…”
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Correction: Genetics of Callous-Unemotional Behavior in Children by Viding, Essi, Price, Thomas S., Jaffee, Sara R., Trzaskowski, Maciej, Davis, Oliver S. P., Meaburn, Emma L., Haworth, Claire M. A., Plomin, Robert

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What Can the Study of Genetics Offer to Educators? by Thomas, Michael S. C., Kovas, Yulia, Meaburn, Emma L., Tolmie, Andrew

“…ABSTRACT This article explores the potential contribution of modern genetic methods and findings to education. It is familiar to hear that the “gene” for this…”
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