Search Results - "Mclone, David G."

Folate Receptor Alpha Upregulates Oct4, Sox2 and Klf4 and Downregulates miR‐138 and miR‐let‐7 in Cranial Neural Crest Cells by Mohanty, Vineet, Shah, Amar, Allender, Elise, Siddiqui, M. Rizwan, Monick, Sarah, Ichi, Shunsuke, Mania‐Farnell, Barbara, G. McLone, David, Tomita, Tadanori, Mayanil, Chandra Shekhar

“…Prenatal folic acid (FA) supplementation prevents neural tube defects. Folate receptor alpha (FRα) is critical for embryonic development, including neural…”
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Nuclear localization of folate receptor alpha: a new role as a transcription factor by Boshnjaku, Vanda, Shim, Kyu-Won, Tsurubuchi, Takao, Ichi, Shunsuke, Szany, Elise V., Xi, Guifa, Mania-Farnell, Barbara, McLone, David G., Tomita, Tadanori, Mayanil, C. Shekhar

“…Folic acid (FA) has traditionally been associated with prevention of neural tube defects; more recent work suggests that it may also be involved in in the…”
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changing incidence of myelomeningocele and its impact on pediatric neurosurgery: a review from the Children's Memorial Hospital by Bowman, Robin M, Boshnjaku, Vanda, McLone, David G

“…Incidence Worldwide, the incidence of neural tube defects (NTDs) varies from 0.17 to 6.39 per 1,000 live births. The declining prevalence of myelomeningocele,…”
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The Chiari II malformation: cause and impact by MCLONE, David G, DIAS, Mark S

“…It is the Chiari II malformation and its effects that determine the quality of life of the individual born with spina bifida. The cause of this malformation…”
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Spina bifida outcome: a 25-year prospective by Bowman, R M, McLone, D G, Grant, J A, Tomita, T, Ito, J A

“…Open spina bifida is the most complex congenital abnormality compatible with long-term survival. This report outlines the 20- to 25-year outcome for our…”
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Epigenetic regulation of sensory neurogenesis in the dorsal root ganglion cell line ND7 by folic acid by Boshnjaku, Vanda, Ichi, Shunsuke, Shen, Yueh-Wei, Puranmalka, Rahul, Mania-Farnell, Barbara, McLone, David G., Tomita, Tadanori, Mayanil, Chandra S.K.

“…The epigenetic mechanism of folic acid (FA) action on dorsal root ganglion (DRG) cell proliferation and sensory neuron differentiation is not well understood…”
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Multidisciplinary spina bifida clinic: the Chicago experience by Shlobin, Nathan A., Yerkes, Elizabeth B., Swaroop, Vineeta T., Lam, Sandi, McLone, David G., Bowman, Robin M.

“…Open spina bifida (open SB) is the most complex congenital abnormality of the central nervous system compatible with long-term survival. Multidisciplinary care…”
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Maternal Intake of Folic Acid and Neural Crest Stem Cells by Mayanil, Chandra S., Ichi, Shunsuke, Farnell, Barbara-Mania, Boshnjaku, Vanda, Tomita, Tadanori, McLone, David G.

“…Maternal folic acid (FA) intake has beneficial effects in preventing neural tube defects and may also play a role in the prevention of adult onset diseases…”
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Current Management Strategies of Hydrocephalus in the Child With Open Spina Bifida by Norkett, William, McLone, David G, Bowman, Robin

“…Symptomatic hydrocephalus is a common condition associated with myelomeningocele (open spina bifida). Traditionally, hydrocephalus was treated with insertion…”
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Folic Acid Remodels Chromatin on Hes1 and Neurog2 Promoters during Caudal Neural Tube Development by Ichi, Shunsuke, Costa, Fabricio F., Bischof, Jared M., Nakazaki, Hiromichi, Shen, Yueh-Wei, Boshnjaku, Vanda, Sharma, Saurabh, Mania-Farnell, Barbara, McLone, David G., Tomita, Tadanori, Soares, Marcelo B., Mayanil, Chandra S.K.

“…The mechanism(s) behind folate rescue of neural tube closure are not well understood. In this study we show that maternal intake of folate prior to conception…”
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The etiology of neural tube defects: the role of folic acid by MCLONE, David G

“…While the cause of neural tube defects in humans is considered to be multifactorial, it is apparent that folic acid can prevent 70% of open neural tube…”
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Tethered cord release: a long-term study in 114 patients : Clinical article by BOWMAN, Robin M, MOHAN, Avinash, ITO, Joy, SEIBLY, Jason M, MCLONE, David G

“…Object All children born with a myelomeningocele at the authors' institution undergo aggressive treatment to maintain or improve functional outcome…”
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Role of Pax3 acetylation in the regulation of Hes1 and Neurog2 by Ichi, Shunsuke, Boshnjaku, Vanda, Shen, Yueh-Wei, Mania-Farnell, Barbara, Ahlgren, Sara, Sapru, Sidanth, Mansukhani, Nikhita, McLone, David G, Tomita, Tadanori, Mayanil, C S K

“…Pax3 plays a role in regulating Hes1 and Neurog2 activity and thereby stem cell maintenance and neurogenesis. A mechanism for Pax3 regulation of these two…”
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Neurosurgical Management of Spina Bifida: Research Issues by Bowman, Robin M, McLone, David G

“…The neurosurgical goal when treating children with spina bifida (predominantly myelomeningocele) is to maintain stable neurological functioning throughout the…”
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Fetal neural tube stem cells from Pax3 mutant mice proliferate, differentiate, and form synaptic connections when stimulated with folic acid by Ichi, Shunsuke, Nakazaki, Hiromichi, Boshnjaku, Vanda, Singh, Ravneet Monny, Mania-Farnell, Barbara, Xi, Guifa, McLone, David G, Tomita, Tadanori, Mayanil, Chandra Shekhar K

“…Although maternal intake of folic acid (FA) prevents neural tube defects in 70% of the population, the exact mechanism of prevention has not been elucidated…”
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Abdominal cerebrospinal fluid pseudocyst: A complication of ventriculoperitoneal shunt in children by Roitberg, B Z, Tomita, T, McLone, D G

“…The present paper is a retrospective analysis of 27 consecutive patients, treated for abdominal cerebrospinal fluid (CSF) pseudocyst at the Children's Memorial…”
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Key basic helix–loop–helix transcription factor genes Hes1 and Ngn2 are regulated by Pax3 during mouse embryonic development by Nakazaki, Hiromichi, Reddy, Anvesh C., Mania-Farnell, Barbara L., Shen, Yueh-Wei, Ichi, Shunsuke, McCabe, Christopher, George, David, McLone, David G., Tomita, Tadanori, Mayanil, C.S.K.

“…Pax3 is expressed early during embryonic development in spatially restricted domains including limb muscle, neural crest, and neural tube. Pax3 functions at…”
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Surgical results of posterior fossa decompression for patients with Chiari I malformation by Navarro, Ramon, Olavarria, Greg, Seshadri, Roopa, Gonzales-Portillo, Gabriel, McLone, David G, Tomita, Tadanori

“…An increasing number of children with Chiari I malformations are coming to the attention of neurosurgeons today, although a consensus on the surgical approach…”
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Myelocystoceles by McLone, David G

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Retethering of transected fatty filum terminales: Clinical article by OGIWARA, Hideki, LYSZCZARZ, Arleta, ALDEN, Tord D, BOWMAN, Robin M, MCLONE, David G, TOMITA, Tadanori

“…Object Untethering of a tethered spinal cord (TSC) by transecting or removing a fatty filum terminale is a relatively simple procedure that can prevent or…”
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