Search Results - "Mckillop, Iain H."

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    Role of fatty acid binding proteins (FABPs) in cancer development and progression by McKillop, Iain H., Girardi, Cara A., Thompson, Kyle J.

    Published in Cellular signalling (01-10-2019)
    “…Fatty acid binding proteins (FABPs) are small, water soluble proteins that bind long chain fatty acids and other biologically active ligands to facilitate…”
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    Altered fatty acid‐binding protein 4 (FABP4) expression and function in human and animal models of hepatocellular carcinoma by Thompson, Kyle J., Austin, Rebecca Garland, Nazari, Shayan S., Gersin, Keith S., Iannitti, David A., McKillop, Iain H.

    Published in Liver international (01-06-2018)
    “…Background and Aims Hepatocellular carcinoma (HCC) is the third leading cause of cancer‐related mortality. Risk factors for developing HCC include viral…”
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    Role of AMPK-SREBP Signaling in Regulating Fatty Acid Binding-4 (FABP4) Expression following Ethanol Metabolism by Attal, Neha, Marrero, Emilio, Thompson, Kyle J, McKillop, Iain H

    Published in Biology (Basel, Switzerland) (04-11-2022)
    “…Fatty acid binding protein-4 ( ) is not normally expressed in the liver but is induced in alcohol-dependent liver disease (ALD)). This study sought to identify…”
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    Chronic Ethanol Feeding Accelerates Hepatocellular Carcinoma Progression in a Sex-Dependent Manner in a Mouse Model of Hepatocarcinogenesis by Brandon-Warner, Elizabeth, Walling, Tracy L., Schrum, Laura W., McKillop, Iain H.

    “…Background:  Chronic ethanol consumption increases the risk of hepatic cirrhosis and hepatocellular carcinoma (HCC). While sex differences exist in…”
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    Fatty acid binding protein-4 promotes alcohol-dependent hepatosteatosis and hepatocellular carcinoma progression by Attal, Neha, Sullivan, Mariel T., Girardi, Cara A., Thompson, Kyle J., McKillop, Iain H.

    Published in Translational oncology (01-01-2021)
    “…•Fatty liver disease (hepatosteatosis) is a hallmark of ALD and NAFLD.•FABP4 is normally expressed in adipocytes and macrophages.•ALD leads to FABP4…”
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    Treatment of spontaneously ruptured hepatocellular carcinoma: use of laparoscopic microwave ablation and washout by Baimas-George, Maria, Watson, Michael, Murphy, Keith J., Sarantou, John, Vrochides, Dionisios, Martinie, John B., Baker, Erin H., Mckillop, Iain H., Iannitti, David A.

    Published in HPB (Oxford, England) (01-03-2021)
    “…Ruptured, or bleeding, hepatocellular carcinoma (rHCC) is a relatively rare disease presentation associated with high acute mortality rates. This study sought…”
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    Platelet Aggregation, Mitochondrial Function and Morphology in Cold Storage: Impact of Resveratrol and Cytochrome c Supplementation by Ekaney, Michael L, Carrillo-Garcia, Juan Carlos, Gonzalez-Gray, Gabrielle, Wilson, Hadley H, Jordan, Mary M, McKillop, Iain H, Evans, Susan L

    Published in Cells (Basel, Switzerland) (30-12-2022)
    “…Donated platelets are critical components of hemostasis management. Extending platelet storage beyond the recommended guidelines (5 days, 22 °C) is of clinical…”
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    Structure and function of proteins in hydrated choline dihydrogen phosphate ionic liquid by Weaver, Katherine D, Vrikkis, Regina M, Van Vorst, Matthew P, Trullinger, Jonathan, Vijayaraghavan, Ranganathan, Foureau, David M, McKillop, Iain H, MacFarlane, Douglas R, Krueger, Joanna K, Elliott, Gloria D

    Published in Physical chemistry chemical physics : PCCP (01-01-2012)
    “…Ionic liquids are being intensely studied as promising media for the stabilization of proteins and other biomolecules. Choline dihydrogen phosphate (CDHP) has…”
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    The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC) by Thompson, Kyle J, Humphries, John R, Niemeyer, David J, Sindram, David, McKillop, Iain H

    “…Chronic heavy alcohol use is an independent risk factor for developing hepatocellular carcinoma (HCC). Sirtuin-1 (Sirt1) is a NAD+-dependent deacetylase…”
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    Resveratrol attenuates hypoxic injury in a primary hepatocyte model of hemorrhagic shock and resuscitation by Powell, Rebecca D, Swet, Jacob H, Kennedy, Kenneth L, Huynh, Toan T, McKillop, Iain H, Evans, Susan L

    “…Oxidative stress following hemorrhagic shock and resuscitation (HSR) is regulated, in part, by inflammatory and apoptotic mediators such as necrosis factor κB…”
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    Expression and function of lysophosphatidic acid receptors (LPARs) 1 and 3 in human hepatic cancer progenitor cells by Zuckerman, Valentina, Sokolov, Eugene, Swet, Jacob H, Ahrens, William A, Showlater, Victor, Iannitti, David A, Mckillop, Iain H

    Published in Oncotarget (19-01-2016)
    “…Hepatocellular carcinoma (HCC) is the most common primary cancer of the liver and is characterized by rapid tumor expansion and metastasis. Lysophosphatidic…”
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    Targeting collagen expression in alcoholic liver disease by Thompson, Kyle J, McKillop, Iain H, Schrum, Laura W

    Published in World journal of gastroenterology : WJG (28-05-2011)
    “…Alcoholic liver disease (ALD) is a leading cause of liver disease and liver-related deaths globally, particularly in developed nations. Liver fibrosis is a…”
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    MicroRNA expression following activated protein C treatment during septic shock by Moore, Cathy C., PhD, McKillop, Iain H., PhD, Huynh, Toan, MD, FCCM

    Published in The Journal of surgical research (01-06-2013)
    “…Abstract Background Sepsis induces systemic stress by augmenting inflammatory and procoagulant responses, resulting in microvascular dysfunction and end organ…”
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    Decreased aquaporin expression leads to increased resistance to apoptosis in hepatocellular carcinoma by Jablonski, Elizabeth M, Adrian Mattocks, M, Sokolov, Eugene, Koniaris, Leonidas G, Hughes, Francis M, Fausto, Nelson, Pierce, Robert H, McKillop, Iain H

    Published in Cancer letters (18-05-2007)
    “…Abstract Cells undergoing apoptosis are characterized by decreased cell size due to changes in intracellular ion concentration and rapid, aquaporin…”
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    Lysophosphatidic acid receptor expression and function in human hepatocellular carcinoma by Sokolov, Eugene, PhD, Eheim, Ashley L., PhD, Ahrens, William A., MD, Walling, Tracy L., BS, Swet, Jacob H., MS, McMillan, Matthew T., BA, Simo, Kerri A., MD, Thompson, Kyle J., PhD, Sindram, David, MD, PhD, McKillop, Iain H., PhD

    Published in The Journal of surgical research (01-03-2013)
    “…Abstract Background Lysophosphatidic acid (LPA) is a ubiquitously expressed phospholipid that regulates diverse cellular functions. Previously identified LPA…”
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