Search Results - "Mckee, Robert W"
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Type IV Pili Promote Clostridium difficile Adherence and Persistence in a Mouse Model of Infection
Published in Infection and immunity (01-05-2018)“…Cyclic diguanylate (c-di-GMP) is a second messenger that regulates the transition from motile to sessile lifestyles in numerous bacteria and controls virulence…”
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Cyclic Diguanylate Inversely Regulates Motility and Aggregation in Clostridium difficile
Published in Journal of Bacteriology (01-07-2012)“…Clostridium difficile-associated disease is increasing in incidence and is costly to treat. Our understanding of how this organism senses its entry into the…”
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Second Messenger Cyclic Di-GMP Regulates Clostridium difficile Toxin Production by Controlling Expression of sigD
Published in Journal of Bacteriology (01-11-2013)“…The Gram-positive obligate anaerobe Clostridium difficile causes potentially fatal intestinal diseases. How this organism regulates virulence gene expression…”
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Regulation of Type IV Pili Contributes to Surface Behaviors of Historical and Epidemic Strains of Clostridium difficile
Published in Journal of bacteriology (01-02-2016)“…The intestinal pathogen Clostridium difficile is an urgent public health threat that causes antibiotic-associated diarrhea and is a leading cause of fatal…”
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5
Texture and quality of chicken sausage formulated with woody breast meat
Published in Poultry science (01-03-2021)“…Woody breast (WB) myopathy is a quality defect, afflicting a large portion of commercial broilers to some degree. The WB myopathy is commonly attributed to…”
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A Nutrient-Regulated Cyclic Diguanylate Phosphodiesterase Controls Clostridium difficile Biofilm and Toxin Production during Stationary Phase
Published in Infection and immunity (01-09-2017)“…The signaling molecule cyclic diguanylate (c-di-GMP) mediates physiological adaptation to extracellular stimuli in a wide range of bacteria. The complex…”
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Validation of Commonly Used Antimicrobial Interventions on Bob Veal Carcasses for Reducing Shiga Toxin-Producing Escherichia coli Surrogate Populations
Published in Journal of food protection (01-07-2021)“…Ruminants are natural reservoirs of Shiga toxin-producing Escherichia coli (STEC), and the STEC can be easily transferred to carcasses during the conversion of…”
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Cyclic Diguanylate Regulates Virulence Factor Genes via Multiple Riboswitches in Clostridium difficile
Published in mSphere (24-10-2018)“…The intracellular signaling molecule cyclic diguanylate (c-di-GMP) regulates many processes in bacteria, with a central role in controlling the switch between…”
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The effects of antimicrobials on quality and sensory characteristics of blade tenderized beef strip loins
Published in Food science & technology (01-08-2019)“…The beef industry utilizes blade tenderization (BT) to enhance tenderness; however, foodborne outbreaks have been associated with BT beef. Therefore,…”
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A systematic analysis of the in vitro and in vivo functions of the HD-GYP domain proteins of Vibrio cholerae
Published in BMC microbiology (25-10-2014)“…The second messenger cyclic diguanylate (c-di-GMP) plays a central role in bacterial adaptation to extracellular stimuli, controlling processes such as…”
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Validation of Antimicrobial Interventions for Reducing Shiga Toxin-Producing Escherichia coli Surrogate Populations during Goat Slaughter and Carcass Chilling
Published in Journal of food protection (01-03-2019)“…Demand and consumption of goat meat is increasing in the United States due to an increase in ethnic populations that prefer goat meat. As ruminant animals,…”
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High-Pressure Processing Helps Meet the Escherichia coli O157:H7 and Shiga Toxin–Producing E. coli (STEC) Performance Standards for Beef Summer Sausage
Published in Meat and muscle biology (19-09-2023)“…The United States Department of Agriculture–Food Safety Inspection Service (USDA-FSIS) performance standards require that manufacturers of fermented beef…”
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Texture of Fermented Summer Sausage With Differing pH, Endpoint Temperature, and High Pressure Processing Times
Published in Meat and muscle biology (29-02-2020)“…The objective was to evaluate the quality and texture of all-beef summer sausages produced with varying degrees of fermentation, endpoint cooking temperatures,…”
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Warm-season annual forages in forage-finishing beef systems: I. Forage yield and quality
Published in Translational animal science (01-03-2019)“…Abstract The demand for a year-round supply of fresh, locally grown, forage-finished beef products has created a need for forage-finishing strategies during…”
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Warm-season annual forages in forage-finishing beef systems: II. Animal performance and carcass characteristics
Published in Translational animal science (01-01-2020)“…More information on expected animal performance and carcass traits of forage-finished steers grazing warm-season annual forages is needed. To achieve this…”
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Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial
Published in The Lancet infectious diseases (09-08-2024)“…The rate of antibiotic resistance continues to grow, outpacing small-molecule-drug development efforts. Novel therapies are needed to combat this growing…”
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Grazing evaluation of pearlillet with and without soybean hull supplementation in a forage-finished beef production system
Published in Journal of animal science (01-07-2019)“…Pearl millet may be a viable forage option in foragefinished beef production systems due to favorable agronomic traits and nutritive value. Therefore, the…”
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The efficacy of antimicrobial interventions on Shiga toxin producing Escherichia coli (STEC) surrogate populations inoculated on beef striploins prior to blade tenderization
Published in Food science & technology (01-01-2020)“…The US meat industry actively seeks antimicrobials to eliminate Shiga toxin-producing Escherichia coli (STEC) in non-intact products. To facilitate this, the…”
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114 Monitoring the impact of shade and housing on physiological response in finishing beef cattle during the summer months in the Southeastern United States
Published in Journal of animal science (28-11-2020)“…Abstract A study was conducted to evaluate the effect of heat stress on blood-gas parameters of beef steers finished with or without shade in the Southeastern…”
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124 Finishing beef cattle under cover reduces heat load and improves efficiency during the summer
Published in Journal of animal science (29-07-2019)“…Abstract Heat-stress in finishing cattle presents a significant risk to efficiency and economic viability. The project objective was to quantify the effects of…”
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