Search Results - "Mckay, Mary A"

Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease by Pandey, Manoj K, Burrow, Thomas A, Rani, Reena, Martin, Lisa J, Witte, David, Setchell, Kenneth D, Mckay, Mary A, Magnusen, Albert F, Zhang, Wujuan, Liou, Benjamin, Khl, Jrg, Grabowski, Gregory A

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Complement drives glucosylceramide accumulation and tissue inflammation in Gaucher disease by Pandey, Manoj K., Burrow, Thomas A., Rani, Reena, Martin, Lisa J., Witte, David, Setchell, Kenneth D., Mckay, Mary A., Magnusen, Albert F., Zhang, Wujuan, Liou, Benjamin, Köhl, Jörg, Grabowski, Gregory A.

“…Complement-activating glycosylceramide-specific autoantibodies drive a self-propagating cycle of glycosylceramide accumulation and inflammation in Gaucher…”
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Complement activation causes oncogene expression in Gaucher disease by Pandey, Manoj K, Magnusen, Albert F, McKay, Mary A, Nyamajenjere, Tsitsi C, DiPasquale, Betsy Ann, Magnusen, Daniel N, Rani, Reena, Witte, David, Grabowski, Gregory A, Köhl, Jörg

“…Abstract GBA1 mutations lead to defective lysosomal glucocerebrosidase resulting in accumulation of glucosylceramide (GC) in Gaucher disease (GD). Patients…”
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Immune cells encounter with α-synuclein fuels neurodegeneration in Parkinson’s disease by Pandey, Manoj K, Gross, Christina, Caballero, Madison, McKay, Mary A, Tiwari, Durgesh, Schroeder, Lindsay M, Gurtler, Michael A, Burrow, Thomas A

“…Abstract GBA1 mutations and increases of neuronal α-synulcein protein (α-syn) are the hallmark of Parkinson’s disease (PD). However, the mechanism, by which…”
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