Search Results - "Mckay, M."

Malignant Glioma: Lessons from Genomics, Mouse Models, and Stem Cells by Chen, Jian, McKay, Renée M., Parada, Luis F.

“…Eighty percent of malignant tumors that develop in the central nervous system are malignant gliomas, which are essentially incurable. Here, we discuss how…”
Get full text

A restricted cell population propagates glioblastoma growth after chemotherapy by Chen, Jian, Li, Yanjiao, Yu, Tzong-Shiue, McKay, Renée M., Burns, Dennis K., Kernie, Steven G., Parada, Luis F.

“…By using a GFP reporter protein expressed selectively in neural stem cells in a mouse model of glioblastoma, a small subset of GFP-positive glioma cells is…”
Get full text

Targeting Mitochondria-Derived Reactive Oxygen Species to Reduce Epithelial Barrier Dysfunction and Colitis by Wang, Arthur, Keita, Åsa V, Phan, Van, McKay, Catherine M, Schoultz, Ida, Lee, Joshua, Murphy, Michael P, Fernando, Maria, Ronaghan, Natalie, Balce, Dale, Yates, Robin, Dicay, Michael, Beck, Paul L, MacNaughton, Wallace K, Söderholm, Johan D, McKay, Derek M

“…Epithelial permeability is often increased in inflammatory bowel diseases. We hypothesized that perturbed mitochondrial function would cause barrier…”
Get full text

Comparing fNIRS signal qualities between approaches with and without short channels by Zhou, Xin, Sobczak, Gabriel, McKay, Colette M, Litovsky, Ruth Y

“…Functional near-infrared spectroscopy (fNIRS) is a non-invasive technique used to measure changes in oxygenated (HbO) and deoxygenated (HbR) hemoglobin,…”
Get full text

Targeting renal cell carcinoma with a HIF-2 antagonist by Chen, Wenfang, Hill, Haley, Christie, Alana, Kim, Min Soo, Holloman, Eboni, Pavia-Jimenez, Andrea, Homayoun, Farrah, Ma, Yuanqing, Patel, Nirav, Yell, Paul, Hao, Guiyang, Yousuf, Qurratulain, Joyce, Allison, Pedrosa, Ivan, Geiger, Heather, Zhang, He, Chang, Jenny, Gardner, Kevin H., Bruick, Richard K., Reeves, Catherine, Hwang, Tae Hyun, Courtney, Kevin, Frenkel, Eugene, Sun, Xiankai, Zojwalla, Naseem, Wong, Tai, Rizzi, James P., Wallace, Eli M., Josey, John A., Xie, Yang, Xie, Xian-Jin, Kapur, Payal, McKay, Renée M., Brugarolas, James

“…The HIF-2 antagonist PT2399 is tested in mice bearing tumourgrafts derived from human renal cell cancers to demonstrate its efficacy, identify markers of…”
Get full text

Linking root structure to functionality: the impact of root system architecture on citrate-enhanced phosphate uptake by Fletcher, Daniel M. McKay, Ruiz, Siul, Dias, Tiago, Petroselli, Chiara, Roose, Tiina

“…• Root citrate exudation is thought to be important for phosphate solubilization. Previous research has concluded that cluster-like roots benefit most from…”
Get full text

Integrating signals from RTKs to ERK MAPK by McKay, M M, Morrison, D K

“…Signals received at the cell surface must be properly transmitted to critical targets within the cell to achieve the appropriate biological response. This…”
Get full text

Sampling and Definitions of Placental Lesions: Amsterdam Placental Workshop Group Consensus Statement by Khong, T Yee, Mooney, Eoghan E, Ariel, Ilana, Balmus, Nathalie C M, Boyd, Theonia K, Brundler, Marie-Anne, Derricott, Hayley, Evans, Margaret J, Faye-Petersen, Ona M, Gillan, John E, Heazell, Alex E P, Heller, Debra S, Jacques, Suzanne M, Keating, Sarah, Kelehan, Peter, Maes, Ann, McKay, Eileen M, Morgan, Terry K, Nikkels, Peter G J, Parks, W Tony, Redline, Raymond W, Scheimberg, Irene, Schoots, Mirthe H, Sebire, Neil J, Timmer, Albert, Turowski, Gitta, van der Voorn, J Patrick, van Lijnschoten, Ineke, Gordijn, Sanne J

“…-The value of placental examination in investigations of adverse pregnancy outcomes may be compromised by sampling and definition differences between…”
Get full text

Applications of Phenomenological Loudness Models to Cochlear Implants by McKay, Colette M

“…Cochlear implants electrically stimulate surviving auditory neurons in the cochlea to provide severely or profoundly deaf people with access to hearing. Signal…”
Get full text

Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade by Gu, Yi-Feng, Cohn, Shannon, Christie, Alana, McKenzie, Tiffani, Wolff, Nicholas, Do, Quyen N, Madhuranthakam, Ananth J, Pedrosa, Ivan, Wang, Tao, Dey, Anwesha, Busslinger, Meinrad, Xie, Xian-Jin, Hammer, Robert E, McKay, Renée M, Kapur, Payal, Brugarolas, James

“…Clear cell renal cell carcinoma (ccRCC) is characterized by and mutations, which are associated with tumors of different grade and prognosis. However, whether…”
Get more information

A large West Antarctic Ice Sheet explains early Neogene sea-level amplitude by Marschalek, J. W., Zurli, L., Talarico, F., van de Flierdt, T., Vermeesch, P., Carter, A., Beny, F., Bout-Roumazeilles, V., Sangiorgi, F., Hemming, S. R., Pérez, L. F., Colleoni, F., Prebble, J. G., van Peer, T. E., Perotti, M., Shevenell, A. E., Browne, I., Kulhanek, D. K., Levy, R., Harwood, D., Sullivan, N. B., Meyers, S. R., Griffith, E. M., Hillenbrand, C.-D., Gasson, E., Siegert, M. J., Keisling, B., Licht, K. J., Kuhn, G., Dodd, J. P., Boshuis, C., De Santis, L., McKay, R. M.

“…Early to Middle Miocene sea-level oscillations of approximately 40–60 m estimated from far-field records 1 – 3 are interpreted to reflect the loss of virtually…”
Get full text

Ice loss from the East Antarctic Ice Sheet during late Pleistocene interglacials by Wilson, David J., Bertram, Rachel A., Needham, Emma F., van de Flierdt, Tina, Welsh, Kevin J., McKay, Robert M., Mazumder, Anannya, Riesselman, Christina R., Jimenez-Espejo, Francisco J., Escutia, Carlota

“…Understanding ice sheet behaviour in the geological past is essential for evaluating the role of the cryosphere in the climate system and for projecting rates…”
Get full text

Pten deletion in adult hippocampal neural stem/progenitor cells causes cellular abnormalities and alters neurogenesis by Amiri, Anahita, Cho, Woosung, Zhou, Jing, Birnbaum, Shari G, Sinton, Christopher M, McKay, Renée M, Parada, Luis F

“…Adult neurogenesis persists throughout life in restricted brain regions in mammals and is affected by various physiological and pathological conditions. The…”
Get full text

TRPA1 controls inflammation and pruritogen responses in allergic contact dermatitis by Liu, Boyi, Escalera, Jasmine, Balakrishna, Shrilatha, Fan, Lu, Caceres, Ana I., Robinson, Eve, Sui, Aiwei, McKay, M. Craig, McAlexander, M. Allen, Herrick, Christina A., Jordt, Sven E.

“…Allergic contact dermatitis is a common skin disease associated with inflammation and persistent pruritus. Transient receptor potential (TRP) ion channels in…”
Get full text

CXCR4/CXCL12 Mediate Autocrine Cell- Cycle Progression in NF1-Associated Malignant Peripheral Nerve Sheath Tumors by Mo, Wei, Chen, Jian, Patel, Amish, Zhang, Liang, Chau, Vincent, Li, Yanjiao, Cho, Woosung, Lim, Kyun, Xu, Jing, Lazar, Alexander J., Creighton, Chad J., Bolshakov, Svetlana, McKay, Renée M., Lev, Dina, Le, Lu Q., Parada, Luis F.

“…Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that arise in connective tissue surrounding peripheral nerves. They occur…”
Get full text

HIF-2 Complex Dissociation, Target Inhibition, and Acquired Resistance with PT2385, a First-in-Class HIF-2 Inhibitor, in Patients with Clear Cell Renal Cell Carcinoma by Courtney, Kevin D, Ma, Yuanqing, Diaz de Leon, Alberto, Christie, Alana, Xie, Zhiqun, Woolford, Layton, Singla, Nirmish, Joyce, Allison, Hill, Haley, Madhuranthakam, Ananth J, Yuan, Qing, Xi, Yin, Zhang, Yue, Chang, Jenny, Fatunde, Oluwatomilade, Arriaga, Yull, Frankel, Arthur E, Kalva, Sanjeeva, Zhang, Song, McKenzie, Tiffani, Reig Torras, Oscar, Figlin, Robert A, Rini, Brian I, McKay, Renée M, Kapur, Payal, Wang, Tao, Pedrosa, Ivan, Brugarolas, James

“…The heterodimeric transcription factor HIF-2 is arguably the most important driver of clear cell renal cell carcinoma (ccRCC). Although considered undruggable,…”
Get full text

Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis by Wang, Shan-Shan, Gu, Yi-Feng, Wolff, Nicholas, Stefanius, Karoliina, Christie, Alana, Dey, Anwesha, Hammer, Robert E., Xie, Xian-Jin, Rakheja, Dinesh, Pedrosa, Ivan, Carroll, Thomas, McKay, Renée M., Kapur, Payal, Brugarolas, James

“…Why different species are predisposed to different tumor spectra is not well understood. In particular, whether the physical location of tumor suppressor genes…”
Get full text

Quantifying citrate-enhanced phosphate root uptake using microdialysis by McKay Fletcher, D. M., Shaw, R., Sánchez-Rodríguez, A. R., Daly, K. R., van Veelen, A., Jones, D. L., Roose, T.

“…Aims Organic acid exudation by plant roots is thought to promote phosphate (P) solubilisation and bioavailability in soils with poorly available nutrients…”
Get full text

East Antarctic ice sheet most vulnerable to Weddell Sea warming by Golledge, N. R., Levy, R. H., McKay, R. M., Naish, T. R.

“…Models predict considerable spatial variability in the magnitude of future climate change around Antarctica, suggesting that some sectors of the continent may…”
Get full text

Examining the Efficacy of a Family Peer Advocate Model for Black and Hispanic Caregivers of Children with Autism Spectrum Disorder by Jamison, J. M., Fourie, E., Siper, P. M., Trelles, M. P., George-Jones, Julia, Buxbaum Grice, A., Krata, J., Holl, E., Shaoul, J., Hernandez, B., Mitchell, L., McKay, M. M., Buxbaum, J. D., Kolevzon, Alexander

“…Autism spectrum disorder (ASD) affects individuals across all racial and ethnic groups, yet rates of diagnosis are disproportionately higher for Black and…”
Get full text