Search Results - "Mcintyre, B. W."

Cytokines and angiogenic factors in patients with metastatic renal cell carcinoma treated with interferon-α: association of pretreatment serum levels with survival by Montero, A.J., Diaz-Montero, C.M., Millikan, R.E., Liu, J., Do, K.-A., Hodges, S., Jonasch, E., McIntyre, B.W., Hwu, P., Tannir, N.

“…To correlate serum cytokine and angiogenic factor (CAF) levels with overall survival (OS) in metastatic renal cell carcinoma (mRCC) treated with interferon-α…”
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Tumor necrosis factor-α provokes a hypertrophic growth response in adult cardiac myocytes by YOKOYAMA, T, NAKANO, M, BEDNARCZYK, J. L, MCINTYRE, B. W, ENTMAN, M, MANN, D. L

“…Tumor necrosis factor-alpha (TNF-alpha) is a pleiotropic cytokine with a broad range of concentration-dependent effects. The recent observation that TNF-alpha…”
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Acquisition of anoikis resistance in human osteosarcoma cells by Dı́az-Montero, C.M., McIntyre, B.W.

“…Under normal circumstances, adhered cells die of anoikis when detached from their extracellular matrix (ECM). Resistance to anoikis has been implicated in the…”
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IL-4 induces adherence of human eosinophils and basophils but not neutrophils to endothelium. Association with expression of VCAM-1 by Schleimer, RP, Sterbinsky, SA, Kaiser, J, Bickel, CA, Klunk, DA, Tomioka, K, Newman, W, Luscinskas, FW, Gimbrone, MA, Jr, McIntyre, BW

“…The present studies were performed to explore potentially selective mechanisms of leukocyte adhesion in an attempt to understand how preferential recruitment…”
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Identification of a murine Peyer's patch--specific lymphocyte homing receptor as an integrin molecule with an alpha chain homologous to human VLA-4 alpha by Holzmann, B, McIntyre, B W, Weissman, I L

“…Lymphocyte homing is controlled by organ-specific interactions of lymphocytes and high endothelial venules (HEV). Adhesion of lymphocytes to Peyer's patch HEV,…”
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A monoclonal antibody to VLA-4 alpha-chain (CDw49d) induces homotypic lymphocyte aggregation by Bednarczyk, JL, McIntyre, BW

“…The complex processes of cellular adhesion involve a variety of receptor to ligand interactions that are extremely important during the development of immune…”
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Fibronectin promotes proliferation of naive and memory T cells by signaling through both the VLA-4 and VLA-5 integrin molecules by Davis, LS, Oppenheimer-Marks, N, Bednarczyk, JL, McIntyre, BW, Lipsky, PE

“…The capacity of purified fibronectin to costimulate human T cell DNA synthesis was examined. Low concentrations of immobilized fibronectin, but not soluble…”
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In an adhesion dependent human gastric adenocarcinoma cell line, integrin ligation without adhesion rescues from anoikis but is not sufficient for cell cycle progression by Caruso, D A, McIntyre, B W

“…STAD cells are the adherent parental apoptotic line from which two sublines were cloned that differed in their response to suspended culturing conditions, one…”
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Inhibition of TNF-α-induced sickle RBC retention in retina by a VLA-4 antagonist by LUTTY, Gerard A, TAOMOTO, Makoto, JINGTAI CAO, MCLEOD, D. Scott, VANDERSLICE, Peter, MCINTYRE, Brad W, FABRY, Mary E, NAGEL, Ronald L

“…Patients with sickle cell disease have elevated circulating levels of cytokines including tumor necrosis factor (TNF) alpha. TNF-alpha stimulates expression by…”
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Adhesion of Human B Cells to Germinal Centers in Vitro Involves VLA-4 and INCAM-110 by Freedman, Arnold S., Munro, J. Michael, Rice, G. Edgar, Bevilacqua, Michael P., Morimoto, Chikao, McIntyre, Bradley W., Rhynhart, Kurt, Pober, Jordan S., Nadler, Lee M.

“…Human B lymphocytes localize and differentiate within the microenvironment of lymphoid germinal centers. A frozen section binding assay was developed for the…”
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Fibronectin Binding Protein A of Staphylococcus aureus Can Mediate Human T Lymphocyte Adhesion and Coactivation by Miyamoto, Yuko J, Wann, Elisabeth R, Fowler, Trent, Duffield, Eric, Hook, Magnus, McIntyre, Bradley W

“…The extracellular matrix protein fibronectin (FN) mediates the adhesion of bacteria as well as T lymphocytes. Mammalian cells express integrins alpha(4)beta(1)…”
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Human CD4+ T cells proliferate to HLA-DR+ allogeneic vascular endothelium. Identification of accessory interactions by Savage, C O, Hughes, C C, McIntyre, B W, Picard, J K, Pober, J S

“…Serially passaged human endothelial cell (EC) cultures will stimulate highly purified peripheral blood CD4+ T cells to proliferate if and only if the EC…”
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Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody by Allison, JP, McIntyre, BW, Bloch, D

“…A panel of hybridomas was constructed by fusion of P3X63Ag8 myeloma cells with spleen cells from a BALB/c mouse that had been immunized with a C57BL/Ka…”
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Convergence between CD98 and integrin‐mediated T‐lymphocyte co‐stimulation by Warren, A. P., Patel, K., Miyamoto, Y., Wygant, J. N., Woodside, D. G., Mcintyre, B. W.

“…Summary CD98 is a widely expressed cell surface heterodimeric glycoprotein, which is rapidly up‐regulated upon activation of T lymphocytes. Monoclonal antibody…”
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Multidimensional flow-cytometric analysis of dendritic cells in peripheral blood of normal donors and cancer patients by SAVARY, C. A, GRAZZIUTTI, M. L, PIERSON, D. L, PELLIS, N. R, REX, J. H, MELICHAR, B, PRZEPIORKA, D, FREEDMAN, R. S, COWART, R. E, COHEN, D. M, ANAISSIE, E. J, WOODSIDE, D. G, MCINTYRE, B. W

“…We studied the potential of multidimensional flow cytometry to evaluate the frequency and maturation/activation status of dendritic cells in minimally…”
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Lymphocyte Surface Antigen L25 Is a Member of the Integrin Receptor Superfamily by McIntyre, B W, Evans, E L, Bednarczyk, J L

“…Monoclonal antibody (mAb) anti-L25 identifies an antigen on the surface of human lymphocytes. This mAb immunoprecipitated three distinct polypeptides of Mr…”
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Expression of a functional laminin receptor (α6β1, very late activation antigen-6) on human eosinophils by GEORAS, S. N, MCINTYRE, B. W, EBISAWA, M, BEDNARCZYK, J. L, STERBINSKY, S. A, SCHLEIMER, R. P, BOCHNER, B. S

“…The mechanisms responsible for the accumulation of eosinophils at sites of allergic and other inflammatory reactions are unknown, but recent studies have…”
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Follicular Non-Hodgkin’s Lymphoma Cell Adhesion to Normal Germinal Centers and Neoplastic Follicles Involves Very Late Antigen-4 and Vascular Cell Adhesion Molecule-1 by Freedman, Arnold S., Munro, J. Michael, Morimoto, Chikao, McIntyre, Bradley W., Rhynhart, Kurt, Lee, Nina, Nadler, Lee M.

“…Follicular lymphomas recapitulate the architecture of germinal centers (GCs) of normal secondary lymphoid follicles. Using an in vitro binding assay, it has…”
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Changes in Gravity Inhibit Lymphocyte Locomotion through Type I Collagen by Pellis, Neal R., Thomas J. Goodwin, Diana Risin, McIntyre, Bradley W., Roland P. Pizzini, Cooper, David, Tacey L. Baker, Glenn F. Spaulding

“…Immunity relies on the circulation of lymphocytes through many different tissues including blood vessels, lymphatic channels, and lymphoid organs. The ability…”
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The mouse T cell receptor: structural heterogeneity of molecules of normal T cells defined by xenoantiserum by McIntyre, B W, Allison, J P

“…We have previously demonstrated that T lymphomas may express clonally specific epitopes that are carried by a T-cell-restricted, disulfide-bonded heterodimeric…”
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