Search Results - "Mccracken, J T"
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Potential adverse effects of amphetamine treatment on brain and behavior: a review
Published in Molecular psychiatry (01-02-2009)“…Amphetamine stimulants have been used medically since early in the twentieth century, but they have a high abuse potential and can be neurotoxic. Although they…”
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Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective
Published in Psychological medicine (01-01-2012)“…Experts have proposed removing obsessive-compulsive disorder (OCD) from the anxiety disorders section and grouping it with putatively related conditions in…”
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Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-07-2009)“…SAP90/PSD95‐associated protein (SAPAP) family proteins are post‐synaptic density (PSD) components that interact with other proteins to form a key scaffolding…”
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Genomewide linkage scan for obsessive-compulsive disorder: evidence for susceptibility loci on chromosomes 3q, 7p, 1q, 15q, and 6q
Published in Molecular psychiatry (01-08-2006)“…Obsessive-compulsive disorder (OCD) is the tenth most disabling medical condition worldwide. Twin and family studies implicate a genetic etiology for this…”
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Biased paternal transmission of SNAP-25 risk alleles in attention-deficit hyperactivity disorder
Published in Molecular psychiatry (01-03-2003)“…Attention-deficit hyperactivity disorder (ADHD) is the most common childhood psychiatric disorder, affecting 5-10% of school-age children. Although the…”
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Obsessive-compulsive disorder: subclassification based on co-morbidity
Published in Psychological medicine (01-09-2009)“…Obsessive-compulsive disorder (OCD) is probably an etiologically heterogeneous condition. Many patients manifest other psychiatric syndromes. This study…”
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Association of SLC6A4 variants with obsessive-compulsive disorder in a large multicenter US family study
Published in Molecular psychiatry (01-01-2011)“…Genetic association studies of SLC6A4 ( SERT ) and obsessive-compulsive disorder (OCD) have been equivocal. We genotyped 1241 individuals in 278 pedigrees from…”
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Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association of ADHD with DRD4 and DRD5
Published in Molecular psychiatry (01-07-2004)“…Attention-deficit hyperactivity disorder (ADHD) is one of the most common childhood behavioral disorders. Genetic factors contribute to the underlying…”
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Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD)
Published in Molecular psychiatry (01-09-2000)“…Attention deficit hyperactivity disorder (ADHD) is a common childhood-onset neurodevelopmental disorder. Evidence from twin, adoption, and family studies…”
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A screen of SLC1A1 for OCD-related alleles
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (01-03-2010)“…SLC1A1, which encodes the neuronal and epithelial glutamate transporter, is a promising candidate gene for obsessive‐compulsive disorder (OCD). In this study,…”
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Gender differences in genetic linkage and association on 11p15 in obsessive-compulsive disorder families
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-01-2009)“…Several clinical and genetic studies have reported gender differences in obsessive–compulsive disorder (OCD). Previously, we conducted a linkage genome scan…”
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Catecholamines in attention-deficit hyperactivity disorder: current perspectives
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-03-1996)“…To provide an update on the "catecholamine hypothesis" of attention-deficit hyperactivity disorder (ADHD). Recent work examining the measurement of the…”
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Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-09-2000)“…To examine familial clustering of attention-deficit/hyperactivity disorder (ADHD), ADHD subtypes, symptoms, and oppositional behaviors in affected sibling…”
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Genome-wide scan of reading ability in affected sibling pairs with attention-deficit hyperactivity disorder: unique and shared genetic effects
Published in Molecular psychiatry (01-05-2004)“…Attention-deficit/hyperactivity disorder (ADHD) and reading disability (RD) are common highly heritable disorders of childhood, which frequently co-occur. Data…”
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Mental health problems and service use among female juvenile offenders: their relationship to criminal history
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-05-2001)“…To describe (1) the level of mental health problems and lifetime use of specialty mental health services and special education programs among incarcerated…”
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Positive effects of methylphenidate on hyperactivity are moderated by monoaminergic gene variants in children with autism spectrum disorders
Published in The pharmacogenomics journal (01-06-2014)“…Methylphenidate (MPH) reduces hyperactive-impulsive symptoms common in children with autism spectrum disorders (ASDs), however, response and tolerability…”
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Adrenal gland volume in major depression: Relationship to basal and stimulated pituitary-adrenal cortical axis function
Published in Biological psychiatry (1969) (15-07-1996)“…We measured adrenal gland volume and both baseline and stimulated pituitary and adrenal cortical hormones in 35 unmedicated, major depressives and 35…”
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A family-based association study of the glutamate transporter gene SLC1A1 in obsessive-compulsive disorder in 378 families
Published in American journal of medical genetics. Part B, Neuropsychiatric genetics (05-09-2009)“…SLC1A encodes the neuronal and epithelial glutamate transporter and was previously tested as a candidate for obsessive–compulsive disorder (OCD) by several…”
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Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies
Published in Translational psychiatry (25-06-2013)“…Second-generation antipsychotic exposure, in both children and adults, carries significant risk for excessive weight gain that varies widely across…”
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Sleep electroencephalographic abnormalities in adolescent depressives : Effects of scopolamine
Published in Biological psychiatry (1969) (01-10-1997)“…In contrast to sleep studies of adult depressives that have consistently demonstrated abnormalities of sleep continuity, slow-wave sleep, and REM sleep,…”
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