Search Results - "McWhorter, Kirklin L."
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Novel Vaccine Technologies in Veterinary Medicine: A Herald to Human Medicine Vaccines
Published in Frontiers in veterinary science (15-04-2021)“…The success of inactivated and live-attenuated vaccines has enhanced livestock productivity, promoted food security, and attenuated the morbidity and mortality…”
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Potent and specific antibiotic combination therapy against Clostridioides difficile
Published in Nature chemical biology (01-07-2024)“…Keratinicyclins and keratinimicins are recently discovered glycopeptide antibiotics. Keratinimicins show broad-spectrum activity against Gram-positive…”
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Combatting melioidosis with chemical synthetic lethality
Published in Proceedings of the National Academy of Sciences - PNAS (12-11-2024)“…Burkholderia thailandensis has emerged as a nonpathogenic surrogate for Burkholderia pseudomallei , the causative agent of melioidosis, and an important…”
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X‑ray Emission Spectroscopy of Single Protein Crystals Yields Insights into Heme Enzyme Intermediates
Published in The journal of physical chemistry letters (12-01-2023)“…Enzyme reactivity is often enhanced by changes in oxidation state, spin state, and metal–ligand covalency of associated metallocofactors. The development of…”
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Insights into Substrate Recognition by the Unusual Nitrating Enzyme RufO
Published in ACS chemical biology (18-08-2023)“…Nitration reactions are crucial for many industrial syntheses; however, current protocols lack site specificity and employ hazardous chemicals. The…”
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