Search Results - "McWhorter, Frances Y"
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Physical and mechanical regulation of macrophage phenotype and function
Published in Cellular and molecular life sciences : CMLS (01-04-2015)“…Macrophages are tissue-resident immune cells that play a critical role in maintaining homeostasis and fighting infection. In addition, these cells are involved…”
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Modulation of macrophage phenotype by cell shape
Published in Proceedings of the National Academy of Sciences - PNAS (22-10-2013)“…Phenotypic polarization of macrophages is regulated by a milieu of cues in the local tissue microenvironment. Although much is known about how soluble factors…”
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Shear forces enhance Toxoplasma gondii tachyzoite motility on vascular endothelium
Published in mBio (01-04-2014)“…Toxoplasma gondii is a highly successful parasite that infects approximately one-third of the human population and can cause fatal disease in immunocompromised…”
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Real‐time imaging of Toxoplasma‐infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers
Published in Cellular microbiology (01-04-2014)“…Summary Peripheral blood monocytes are actively infected by Toxoplasma gondii and can function as ‘Trojan horses’ for parasite spread in the bloodstream. Using…”
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Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platform
Published in Integrative biology (Cambridge) (11-07-2016)“…Secreted proteins play a major role in orchestrating the response of cell populations. However, a quantitative understanding of the dynamic changes in protein…”
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Journal Article -
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Contrast-enhanced imaging of SPIO-labeled platelets using magnetomotive ultrasound
Published in Physics in medicine & biology (21-10-2013)“…The ability to image platelets in vivo can provide insight into blood clotting processes and coagulopathies, and aid in identifying sites of vascular…”
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Journal Article -
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Macrophage secretion heterogeneity in engineered microenvironments revealed using a microwell platformElectronic supplementary information (ESI) available. See DOI: 10.1039/c6ib00053c
Published 11-07-2016“…Secreted proteins play a major role in orchestrating the response of cell populations. However, a quantitative understanding of the dynamic changes in protein…”
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Journal Article -
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Real-time imaging of Toxoplasma -infected human monocytes under fluidic shear stress reveals rapid translocation of intracellular parasites across endothelial barriers: Transendothelial migration of Toxoplasma -infected monocytes
Published in Cellular microbiology (01-04-2014)Get full text
Journal Article -
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Geometric Control of Macrophage Phenotype and Function: A Single Cell Analysis
Published 01-01-2015“…Macrophages are tissue-resident immune cells that play critical roles in development, metabolic regulation, maintenance of tissue homeostasis and defense…”
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Dissertation