Search Results - "McWhirter, John R"

Antibodies Selected from Combinatorial Libraries Block a Tumor Antigen That Plays a Key Role in Immunomodulation by McWhirter, John R., Kretz-Rommel, Anke, Saven, Alan, Maruyama, Toshiaki, Potter, Kathleen N., Mockridge, C. Ian, Ravey, E. Prenn, Qin, Fenghua, Bowdish, Katherine S.

“…We searched for cell-surface-associated proteins overexpressed on B cell chronic lymphocytic leukemia (CLL) to use as therapeutic antibody targets. Antibodies…”
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Fgf15 is required for proper morphogenesis of the mouse cardiac outflow tract by Vincentz, Joshua W., McWhirter, John R., Murre, Cornelis, Baldini, Antonio, Furuta, Yasuhide

“…Evidence in animal models indicates that signaling networks functioning in the developing pharyngeal arches regulate stereotyped processes critical for proper…”
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A Short Isoform of Coagulation Factor XII mRNA Is Expressed by Neurons in the Human Brain by Zamolodchikov, Daria, Bai, Yu, Tang, Yajun, McWhirter, John R., Macdonald, Lynn E., Alessandri-Haber, Nicole

“…Coagulation factor XII (FXII) is synthesized in the liver and secreted into the circulation, where it initiates the contact activation system. Although…”
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Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties by Macdonald, Lynn E., Meagher, Karoline A., Franklin, Matthew C., Levenkova, Natasha, Hansen, Johanna, Badithe, Ashok T., Zhong, Maggie, Krueger, Pamela, Rafique, Ashique, Tu, Naxin, Shevchuk, James, Wadhwa, Saurabh, Ehrlich, George, Bautista, Joannie, Grant, Craig, Esau, Lakeisha, Poueymirou, William T., Auerbach, Wojtek, Morton, Lori, Babb, Robert, Chen, Gang, Huang, Tammy, MacDonald, Douglas, Graham, Kenneth, Gurer, Cagan, Voronina, Vera A., McWhirter, John R., Guo, Chunguang, Yancopoulos, George D., Murphy, Andrew J.

“…We describe a Kappa-on-Heavy (KoH) mouse that produces a class of highly diverse, fully human, antibody-like agents. This mouse was made by replacing the…”
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Humanization of T cell-mediated immunity in mice by Moore, Michael J, Zhong, Maggie, Hansen, Johanna, Gartner, Hans, Grant, Craig, Huang, Mei, Harris, Faith M, Tu, Naxin, Bowerman, Natalie A, Edelmann, Kurt H, Barry, Thomas, Herbin, Olivier, Tay, Chin-Siean, DiLillo, David J, Decker, Corinne E, Levenkova, Natasha, Shevchuk, James, Dhanik, Ankur, Meagher, Karoline A, Karr, Amanda, Roos, Jan, Lee, Wen-Yi, Suh, David, Eckersdorff, Mark, Meagher, T Craig, Koss, Matthew, Esau, Lakeisha, Sleeman, Matthew A, Babb, Robert, Chen, Gang, Kyratsous, Christos A, Poueymirou, William T, McWhirter, John R, Voronina, Vera A, Guo, Chunguang, Gurer, Cagan, Yancopoulos, George D, Murphy, Andrew J, Macdonald, Lynn E

“…Despite the enormous promise of T cell therapies, the isolation and study of human T cell receptors (TCRs) of dedicated specificity remains a major challenge…”
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Effect of Bcr sequences on the cellular function of the Bcr-Abl oncoprotein by MCWHIRTER, J. R, WANG, J. Y. J

“…In Philadelphia chromosome (Ph1)-positive human leukemia, the c-Abl tyrosine kinase is activated by fusion to sequences encoded by the breakpoint cluster…”
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A novel fibroblast growth factor gene expressed in the developing nervous system is a downstream target of the chimeric homeodomain oncoprotein E2A-Pbx1 by McWhirter, J R, Goulding, M, Weiner, J A, Chun, J, Murre, C

“…Pbx1 is a homeodomain transcription factor that has the ability to form heterodimers with homeodomain proteins encoded by the homeotic selector (Hox) gene…”
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Oncogenic Homeodomain Transcription Factor E2A-Pbx1 Activates a Novel WNT Gene in Pre-B Acute Lymphoblastoid Leukemia by McWhirter, J R, Neuteboom, S T, Wancewicz, E V, Monia, B P, Downing, J R, Murre, C

“…A large fraction of pediatric pre-B acute lymphoblastoid leukemias (ALL) consistently contain a t(1;19) chromosomal translocation. The t(1;19) translocation…”
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Correction: FGF15 promotes neurnogenesis and opposes FGF8 function during neocortical development by Borello, Ugo, Cobos, Inma, Long, Jason E, McWhirter, John R, Murre, Cornelis, Rubenstein, John LR

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Allosteric Modulation of AMPA-Type Glutamate Receptors Increases Activity of the Promoter for the Neural Cell Adhesion Molecule, N-CAM by Holst, Brent D., Vanderklish, Peter W., Krushel, Leslie A., Zhou, Wei, Langdon, Ronald B., McWhirter, John R., Edelman, Gerald M., Crossin, Kathryn L.

“…To study regulation in vivo of the promoter for the neural cell adhesion molecule, N-CAM, we have used homologous recombination to insert the bacterial lacZ…”
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FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development by Borello, Ugo, Cobos, Inma, Long, Jason E, McWhirter, John R, Murre, Cornelis, Rubenstein, John L R

“…Growth, differentiation and regional specification of telencephalic domains, such as the cerebral cortex, are regulated by the interplay of secreted proteins…”
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Oxygen Mass Transfer Fundamentals of Surface Aerators by McWhirter, John R, Chern, Jia-Ming, Hutter, Joesph C

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A coiled-coil oligomerization domain of Bcr is essential for the transforming function of Bcr-Abl oncoproteins by MCWHIRTER, J. R, GALASSO, D. L, WANG, J. Y. J

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Activation of Tyrosine Kinase and Microfilament-Binding Functions of c-abl by bcr Sequences in bcr/abl Fusion Proteins by Mcwhirter, John R., Wang, Jean Y. J.

“…Chronic myelogenous leukemia and one type of acute lymphoblastic leukemia are characterized by a 9;22 chromosome translocation in which 5′ sequences of the bcr…”
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Erratum to: FGF15 promotes neurnogenesis and opposes FGF8 function during neocortical development by Borello, Ugo, Cobos, Inma, Long, Jason E, McWhirter, John R, Murre, Cornelis, Rubenstein, John LR

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The human leukemia oncogene bcr-abl abrogates the anchorage requirement but not the growth factor requirement for proliferation by Renshaw, Mark W., McWhirter, John R., Wang, Jean Y. J.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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A Coiled-Coil Oligomerization Domain of Bcr Is Essential for the Transforming Function of Bcr-Abl Oncoproteins by McWhirter, John R., Galasso, Debora L., Wang, Jean Y. J.

“…In Philadelphia chromosome-positive human leukemias, the c-abl proto-oncogene on chromosome 9 becomes fused to the bcr gene on chromosome 22, and chimeric…”
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