Search Results - "McShea, A."

Prenatal inflammation is associated with adverse neonatal outcomes by Bastek, Jamie A., MD, MSCE, Weber, Anita L., PhD, McShea, Meghan A., BS, Ryan, Meghan E., BA, Elovitz, Michal A., MD

“…Objective The purpose of this study was to determine whether prenatal inflammation (as assessed by clinical chorioamnionitis, maternal temperature >38°C, or…”
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Environmental variables as potential modifiable risk factors of preterm birth in Philadelphia, PA by Bastek, Jamie A., MD, MSCE, Sammel, Mary D., ScD, Jackson, Tara D., PhD, Ryan, Meghan E., BA, McShea, Meghan A., BS, Elovitz, Michal A., MD

“…Objective To examine whether variation in neighborhood context is associated with preterm birth (PTB) outcomes and gestational age (GA) at delivery in…”
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Abnormal expression of the cell cycle regulators P16 and CDK4 in Alzheimer's disease by McShea, A, Harris, PL, Webster, KR, Wahl, AF, Smith, MA

“…In this study, we demonstrate that two important regulators of the cell cycle, cyclin-dependent kinase-4 and its inhibitor p16, are increased in the brains of…”
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A Case Study Comparing Heterogeneous Lysine- and Site-Specific Cysteine-Conjugated Maytansinoid Antibody-Drug Conjugates (ADCs) Illustrates the Benefits of Lysine Conjugation by Yoder, Nicholas C, Bai, Chen, Tavares, Daniel, Widdison, Wayne C, Whiteman, Kathleen R, Wilhelm, Alan, Wilhelm, Sharon D, McShea, Molly A, Maloney, Erin K, Ab, Olga, Wang, Lintao, Jin, Shan, Erickson, Hans K, Keating, Thomas A, Lambert, John M

“…Antibody-drug conjugates are an emerging class of cancer therapeutics constructed from monoclonal antibodies conjugated with small molecule effectors…”
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Re-entry into the cell cycle: a mechanism for neurodegeneration in Alzheimer disease by McShea, A., Wahl, A.F., Smith, M.A.

“…Several recent findings demonstrated increased expression of cell cycle-related proteins in the degenerating neurons found in Alzheimer disease. We hypothesize…”
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Design, synthesis and evaluation of novel, potent DNA alkylating agents and their antibody-drug conjugates (ADCs) by Reid, Emily E., Archer, Katie E., Shizuka, Manami, McShea, Molly A., Maloney, Erin K., Ab, Olga, Lanieri, Leanne, Wilhelm, Alan, Ponte, Jose F., Yoder, Nicholas C., Chari, Ravi V.J., Miller, Michael L.

“…[Display omitted] Antibody-drug conjugates (ADCs) incorporating potent indolinobenzodiazepine (IGN) DNA alkylators as the cytotoxic payload are currently…”
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Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers by Bialucha, Carl U, Collins, Scott D, Li, Xiao, Saxena, Parmita, Zhang, Xiamei, Dürr, Clemens, Lafont, Bruno, Prieur, Pierric, Shim, Yeonju, Mosher, Rebecca, Lee, David, Ostrom, Lance, Hu, Tiancen, Bilic, Sanela, Rajlic, Ivana Liric, Capka, Vladimir, Jiang, Wei, Wagner, Joel P, Elliott, GiNell, Veloso, Artur, Piel, Jessica C, Flaherty, Meghan M, Mansfield, Keith G, Meseck, Emily K, Rubic-Schneider, Tina, London, Anne Serdakowski, Tschantz, William R, Kurz, Markus, Nguyen, Duc, Bourret, Aaron, Meyer, Matthew J, Faris, Jason E, Janatpour, Mary J, Chan, Vivien W, Yoder, Nicholas C, Catcott, Kalli C, McShea, Molly A, Sun, Xiuxia, Gao, Hui, Williams, Juliet, Hofmann, Francesco, Engelman, Jeffrey A, Ettenberg, Seth A, Sellers, William R, Lees, Emma

“…Despite an improving therapeutic landscape, significant challenges remain in treating the majority of patients with advanced ovarian or renal cancer. We…”
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Biomarkers and Cervical Length to Predict Spontaneous Preterm Birth in Asymptomatic High-Risk Women by Bastek, Jamie A., Hirshberg, Adi, Chandrasekaran, Suchitra, Owen, Carter M., Heiser, Laura M., Araujo, Brittany A., McShea, Meghan A., Ryan, Meghan E., Elovitz, Michal A.

“…To investigate whether biomarkers from different pathways of spontaneous preterm birth (cervical membrane degradation [fetal fibronectin], cervical remodeling…”
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Clinical Prediction Rules for Preterm Birth in Patients Presenting With Preterm Labor by BASTEK, Jamie A, SAMMEL, Mary D, SRINIVAS, Sindhu K, MCSHEA, Meghan A, FOREMAN, Markley N, ELOVITZ, Michal A, METLAY, Joshua P

“…To develop prediction rules to identify which women with preterm labor are at greatest risk for delivery within 10 days and before 37 weeks of gestation using…”
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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates by Catcott, Kalli C, McShea, Molly A, Bialucha, Carl Uli, Miller, Kathy L, Hicks, Stuart W, Saxena, Parmita, Gesner, Thomas G, Woldegiorgis, Mikias, Lewis, Megan E, Bai, Chen, Fleming, Michael S, Ettenberg, Seth A, Erickson, Hans K, Yoder, Nicholas C

“…Antibody-drug conjugates (ADCs) are of great interest as targeted cancer therapeutics. Preparation of ADCs for early stage screening is constrained by…”
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Abelson interactor-1 (ABI-1) interacts with MRL adaptor protein MIG-10 and is required in guided cell migrations and process outgrowth in C. elegans by McShea, Molly A., Schmidt, Kristopher L., Dubuke, Michelle L., Baldiga, Christina E., Sullender, Meagan E., Reis, Andrea L., Zhang, Subaiou, O'Toole, Sean M., Jeffers, Mary C., Warden, Rachel M., Kenney, Allison H., Gosselin, Jennifer, Kuhlwein, Mark, Hashmi, Sana K., Stringham, Eve G., Ryder, Elizabeth F.

“…Directed cell migration and process outgrowth are vital to proper development of many metazoan tissues. These processes are dependent on reorganization of the…”
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The soluble receptor for advanced glycation end products can prospectively identify patients at greatest risk for preterm birth by Bastek, Jamie A., Brown, Amy G., Foreman, Markley N., McShea, Meghan A., Anglim, Laura M., Adamczak, Joanna E., Elovitz, Michal A.

“…Objective: Our primary objective was to determine whether there was an association between levels of antenatal maternal serum soluble RAGE (sRAGE), drawn at…”
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526: Unraveling the racial disparity in preterm birth: experiences of discrimination are associated with preterm birth and low birth weight in black women by Srinivas, Sindhu K, Bastek, Jamie, McShea, Meghan A, Foreman, Markley N, Elovitz, Michal A

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482: Clinical prediction rules for preterm birth can risk stratify patients presenting with preterm labor by Bastek, Jamie A, Sammel, Mary D, Srinivas, Sindhu K, McShea, Meghan A, Foreman, Markley N, Elovitz, Michal A, Metlay, Joshua P

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491: What prevents eligible patients from receiving 17-alpha-hydroxyprogesterone caproate therapy? Important considerations for the clinician by Adamczak, Joanna E, Bastek, Jamie A, Srinivas, Sindhu K, Foreman, Markley N, McShea, Meghan A, Elovitz, Michal A

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Identification and Characterization of Human Cytomegalovirus-Encoded MicroRNAs by GREY, Finn, ANTONIEWICZ, Andy, ALLEN, Edwards, SAUGSTAD, Julie, MCSHEA, Andy, CARRINGTON, James C, NELSON, Jay

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CombiMatrix oligonucleotide arrays: Genotyping and gene expression assays employing electrochemical detection by Ghindilis, Andrey L., Smith, Maria W., Schwarzkopf, Kevin R., Roth, Kristian M., Peyvan, Kia, Munro, Sandra B., Lodes, Michael J., Stöver, Axel G., Bernards, Karen, Dill, Kilian, McShea, Andy

“…Electrochemical detection has been developed and assay performances studied for the CombiMatrix oligonucleotide microarray platform that contains 12,544…”
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High-level expression of functional human thrombomodulin in cultured porcine aortic endothelial cells by Wrighton, C J, Kopp, C W, McShea, A, Vetr, H, Bach, F H

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Fully Integrated Miniature Device for Automated Gene Expression DNA Microarray Processing by Liu, Robin Hui, Nguyen, Tai, Schwarzkopf, Kevin, Fuji, H. Sho, Petrova, Alla, Siuda, Tony, Peyvan, Kia, Bizak, Michael, Danley, David, McShea, Andy

“…A DNA microarray with 12 000 features was integrated with a microfluidic cartridge to automate the fluidic handling steps required to carry out a gene…”
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Use of Semiconductor-Based Oligonucleotide Microarrays for Influenza A Virus Subtype Identification and Sequencing by Lodes, Michael J, Suciu, Dominic, Elliott, Mark, Stover, Axel G, Ross, Marty, Caraballo, Marcelo, Dix, Kim, Crye, James, Webby, Richard J, Lyon, Wanda J, Danley, David L, McShea, Andrew

“…In the face of concerns over an influenza pandemic, identification of virulent influenza A virus isolates must be obtained quickly for effective responses…”
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