Search Results - "McRae, A"

Efficacy and Safety of Dapagliflozin in Patients With Acute Heart Failure by Cox, Zachary L., Collins, Sean P., Hernandez, Gabriel A., McRae, A. Thomas, Davidson, Beth T., Adams, Kirkwood, Aaron, Mark, Cunningham, Luke, Jenkins, Cathy A., Lindsell, Christopher J., Harrell, Frank E., Kampe, Christina, Miller, Karen F., Stubblefield, William B., Lindenfeld, JoAnn

“…The primary goals during acute heart failure (AHF) hospitalization are decongestion and guideline-directed medical therapy (GDMT) optimization. Unlike…”
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The perineuronal net component of the extracellular matrix in plasticity and epilepsy by McRae, Paulette A., Porter, Brenda E.

“…► Composition of the extracellular matrix of the central nervous system. ► Specialized perineuronal net component of matrix found around interneurons. ► During…”
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Effect of a Hospital and Postdischarge Quality Improvement Intervention on Clinical Outcomes and Quality of Care for Patients With Heart Failure With Reduced Ejection Fraction: The CONNECT-HF Randomized Clinical Trial by DeVore, Adam D, Granger, Bradi B, Fonarow, Gregg C, Al-Khalidi, Hussein R, Albert, Nancy M, Lewis, Eldrin F, Butler, Javed, Piña, Ileana L, Allen, Larry A, Yancy, Clyde W, Cooper, Lauren B, Felker, G. Michael, Kaltenbach, Lisa A, McRae, A. Thomas, Lanfear, David E, Harrison, Robert W, Disch, Maghee, Ariely, Dan, Miller, Julie M, Granger, Christopher B, Hernandez, Adrian F

“…IMPORTANCE: Adoption of guideline-directed medical therapy for patients with heart failure is variable. Interventions to improve guideline-directed medical…”
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Liver‐specific deletion of de novo DNA methyltransferases protects against glucose intolerance in high‐fat diet‐fed male mice by Yao, S., Prates, K., Freydenzon, A., Assante, G., McRae, A. F., Morris, M. J., Youngson, N. A.

“…Alterations to gene transcription and DNA methylation are a feature of many liver diseases including fatty liver disease and liver cancer. However, it is…”
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Efficacy and safety of dapagliflozin in acute heart failure: Rationale and design of the DICTATE-AHF trial by Cox, Zachary L, Collins, Sean P, Aaron, Mark, Hernandez, Gabriel A, III, A Thomas McRae, Davidson, Beth T, Fowler, Mike, Lindsell, Christopher J, Jr, Frank E Harrell, Jenkins, Cathy A, Kampe, Christina, Miller, Karen F, Stubblefield, William B, Lindenfeld, JoAnn

“…Dapagliflozin, a sodium-glucose cotransporter-2 inhibitor, reduces cardiovascular death and worsening heart failure in patients with chronic heart failure and…”
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Extracellular mixed histones are neurotoxic and modulate select neuroimmune responses of glial cells by Da Silva, Dylan E, Richards, Christy M, McRae, Seamus A, Riar, Ishvin, Yang, Sijie Shirley, Zurfluh, Noah E, Gibon, Julien, Klegeris, Andis

“…Although histone proteins are widely known for their intranuclear functions where they organize DNA, all five histone types can also be released into the…”
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Perineuronal net degradation in epilepsy by Rankin‐Gee, Elyse K., McRae, Paulette A., Baranov, Esther, Rogers, Stephanie, Wandrey, Luke, Porter, Brenda E.

“…Summary Objective We previously reported loss of perineuronal net (PN) immunohistochemical staining around parvalbumin‐positive interneurons in the hippocampus…”
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Sensory Deprivation Alters Aggrecan and Perineuronal Net Expression in the Mouse Barrel Cortex by McRae, Paulette A, Rocco, Mary M, Kelly, Gail, Brumberg, Joshua C, Matthews, Russell T

“…An important role for the neural extracellular matrix in modulating cortical activity-dependent synaptic plasticity has been established by a number of recent…”
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Monotone iterative technique and existence results for fractional differential equations by McRae, F.A.

“…Using the method of upper and lower solutions, an existence result for IVP of Riemann–Liouville fractional differential equation is studied. Also, the monotone…”
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Protein kinase A negatively regulates Ca2+ signalling in Toxoplasma gondii by Uboldi, Alessandro D, Wilde, Mary-Louise, McRae, Emi A, Stewart, Rebecca J, Dagley, Laura F, Yang, Luning, Katris, Nicholas J, Hapuarachchi, Sanduni V, Coffey, Michael J, Lehane, Adele M, Botte, Cyrille Y, Waller, Ross F, Webb, Andrew I, McConville, Malcolm J, Tonkin, Christopher J

“…The phylum Apicomplexa comprises a group of obligate intracellular parasites that alternate between intracellular replicating stages and actively motile…”
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Increased metalloproteinase activity in the hippocampus following status epilepticus by Dubey, Deepti, McRae, Paulette A, Rankin-Gee, Elyse K, Baranov, Esther, Wandrey, Luke, Rogers, Stephanie, Porter, Brenda E

“…Highlights • Total MMP activity increases after status epilepticus. • MMP13 activity increases after status epilepticus. • MMP3 and MMP13 mRNA levels increase…”
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Persistent decrease in multiple components of the perineuronal net following status epilepticus by McRae, Paulette A., Baranov, Esther, Rogers, Stephanie L., Porter, Brenda E.

“…In the rodent model of temporal lobe epilepsy, there is extensive synaptic reorganization within the hippocampus following a single prolonged seizure event,…”
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A Model for the Temperature Distribution in a Rolled Joint in a CANDU Reactor Exploiting the Decomposition of the β-Zr Phase by McRae, Glenn A., Griffiths, Malcolm, Coleman, Christopher E.

“…A competing-rates model is presented to account for operational changes in the metastable β-Zr phase of the Zr-2.5Nb alloy used to make CANDU reactor pressure…”
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Few-Hundred GHz Carbon Nanotube Nanoelectromechanical Systems (NEMS) by Island, J. O, Tayari, V, McRae, A. C, Champagne, A. R

“…We study 23–30 nm long suspended single-wall carbon nanotube quantum dots and observe both their stretching and bending vibrational modes. We use…”
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Impact of CONSORT extension for cluster randomised trials on quality of reporting and study methodology: review of random sample of 300 trials, 2000-8 by Ivers, N M, Taljaard, M, Dixon, S, Bennett, C, McRae, A, Taleban, J, Skea, Z, Brehaut, J C, Boruch, R F, Eccles, M P, Grimshaw, J M, Weijer, C, Zwarenstein, M, Donner, A

“…Objective To assess the impact of the 2004 extension of the CONSORT guidelines on the reporting and methodological quality of cluster randomised trials.Design…”
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Dementia: is it time for targeted national screening? by Davis, G, Baboolal, N, McRae, A, Stewart, R

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Giant electron-hole transport asymmetry in ultra-short quantum transistors by McRae, A. C., Tayari, V., Porter, J. M., Champagne, A. R.

“…Making use of bipolar transport in single-wall carbon nanotube quantum transistors would permit a single device to operate as both a quantum dot and a…”
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Localized Negative Genetic Correlation Constrains Microevolution of Coat Color in Wild Sheep by Gratten, J, Wilson, A.J, McRae, A.F, Beraldi, D, Visscher, P.M, Pemberton, J.M, Slate, J

“…The evolutionary changes that occur over a small number of generations in natural populations often run counter to what is expected on the basis of the…”
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Teasing apart "the tangled web" of influence of policy dialogues: lessons from a case study of dialogues about healthcare reform options for Canada by Mulvale, Gillian, McRae, Samantha A, Milicic, Sandra

“…The knowledge exchange literature suggests that policy dialogues are intended to enhance short-, medium- and long-term capacities of individuals, organizations…”
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ENT and airways in the emergency department: national survey of junior doctors' knowledge and skills by Whitcroft, K L, Moss, B, Mcrae, A

“…Given the urgent nature of ENT emergencies, appropriate knowledge is required amongst front-line staff. Junior doctors account for almost one quarter of…”
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