Search Results - "McQuade, Leon R."
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Effect of N-acetylcysteine infusion on exercise-induced modulation of insulin sensitivity and signaling pathways in human skeletal muscle
Published in American journal of physiology: endocrinology and metabolism (15-08-2015)“…-Reactive oxygen species (ROS) produced in skeletal muscle may play a role in potentiating the beneficial responses to exercise; however, the effects of…”
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Capping dietary starch:protein ratios in moderately reduced crude protein, wheat-based diets showed promise but further reductions generated inferior growth performance in broiler chickens
Published in Animal Nutrition (01-06-2020)“…The hypothesis that capping dietary starch:protein ratios would enhance the performance of broiler chickens offered reduced-crude protein (CP) diets was tested…”
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Assessment of limiting dietary amino acids in broiler chickens offered reduced crude protein diets
Published in Animal Nutrition (01-09-2022)“…As lowering crude protein (CP) in poultry diets continues to minimize amino acid excess, it is important to understand the limiting order of amino acids and…”
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Graded methionine dietary inclusions influence growth performance and apparent ileal amino acid digestibility coefficients and disappearance rates in broiler chickens
Published in Animal Nutrition (01-03-2022)“…Graded quantities of 1.38, 2.76 and 4.14 g/kg L-methionine were included in a control diet formulated to contain 3.07 g/kg digestible methionine. Each of the 4…”
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Implications of excreta uric acid concentrations in broilers offered reduced-crude protein diets and dietary glycine requirements for uric acid synthesis
Published in Animal Nutrition (01-12-2021)“…In a previous experiment, male Ross 308 broiler chickens were offered dietary treatments with 3 levels of crude protein (222, 193, 165 g/kg) and 3 feed grains…”
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Protein digestive dynamics of meat and bone meals in broiler chickens
Published in Animal Nutrition (01-12-2020)“…This study determined the variations in protein digestibilities and digestion rates in broiler chickens offered diets containing 7 different meat and bone…”
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Reducing agent and exogenous protease additions, individually and in combination, to wheat- and sorghum-based diets interactively influence parameters of nutrient utilisation and digestive dynamics in broiler chickens
Published in Animal Nutrition (01-12-2016)“…The objective of the study was to investigate the possibility that tandem inclusions of a reducing agent and a protease may advantage chicken-meat production…”
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Growth and Differentiation of Embryoid Bodies Derived from Human Embryonic Stem Cells: Effect of Glucose and Basic Fibroblast Growth Factor
Published in Biology of reproduction (01-12-2005)“…Differentiation of embryonic stem (ES) cells generally occurs after formation of three-dimensional cell aggregates, known as embryoid bodies (EBs). This…”
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Inherited Surfactant Deficiency Caused by Uniparental Disomy of Rare Mutations in the Surfactant Protein-B and ATP Binding Cassette, Subfamily A, Member 3 Genes
Published in The Journal of pediatrics (01-12-2009)“…Objective To characterize inheritance of homozygous, rare, recessive loss-of-function mutations in surfactant protein-B ( SFTPB ) or ATP binding cassette,…”
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Proteomics of Huntington’s Disease-Affected Human Embryonic Stem Cells Reveals an Evolving Pathology Involving Mitochondrial Dysfunction and Metabolic Disturbances
Published in Journal of proteome research (05-12-2014)“…Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder caused by a mutation in the Huntingtin gene, where excessive (≥36) CAG repeats…”
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Overexpression of αvβ6 Integrin Alters the Colorectal Cancer Cell Proteome in Favor of Elevated Proliferation and a Switching in Cellular Adhesion That Increases Invasion
Published in Journal of proteome research (07-06-2013)“…Many proteins enhance cancer progression toward life-threatening metastases. These include linking proteins called integrins that mediate cell adhesion to the…”
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Improved Membrane Proteomics Coverage of Human Embryonic Stem Cells by Peptide IPG-IEF
Published in Journal of proteome research (04-12-2009)“…Protein biomarkers are fundamental tools for the characterization of stem cells and for tracking their differentiation and maturation down developmental…”
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Identification of Potential Pluripotency Determinants for Human Embryonic Stem Cells Following Proteomic Analysis of Human and Mouse Fibroblast Conditioned Media
Published in Journal of proteome research (01-09-2007)“…The unique pluripotential characteristic of human embryonic stem cells heralds their use in fields such as medicine, biotechnology, biopharmaceuticals, and…”
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Growth and Differentiation of Embryoid Bodies Derived from Human Embryonic Stem Cells: Effect of Glucose and Basic Fibroblast Growth Factor1
Published in Biology of reproduction (01-12-2005)“…Differentiation of embryonic stem (ES) cells generally occurs after formation of three-dimensional cell aggregates, known as embryoid bodies (EBs). This…”
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N-acetylcysteine alters substrate metabolism during high-intensity cycle exercise in well-trained humans
Published in Applied physiology, nutrition, and metabolism (01-12-2013)“…We investigated the effects of N-acetylcysteine (NAC) on metabolism during fixed work rate high-intensity interval exercise (HIIE) and self-paced 10-min…”
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Transplantation of 3D scaffolds seeded with human embryonic stem cells: biological features of surrogate tissue and teratoma-forming potential
Published in Regenerative medicine (01-05-2007)“…To generate complex surrogate tissue by transplanting 3D scaffolds seeded with human embryonic stem cells (hESCs) between the liver lobules of severe combined…”
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A proteome analysis of conditioned media from human neonatal fibroblasts used in the maintenance of human embryonic stem cells
Published in Proteomics (Weinheim) (01-03-2005)“…The pathways involved in the maintenance of human embryonic stem (hES) cells remain largely unknown, although some signaling pathways have been identified in…”
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Maize-based diets are more conducive to crude protein reductions than wheat-based diets for broiler chickens
Published in Animal feed science and technology (01-05-2021)“…•165 g/kg crude protein (CP) maize-based diets were superior to wheat-based diets.•222 and 165 g/kg CP maize-based diets supported very similar growth…”
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The influence of exogenous phytase on the post-enteral availability of amino acids in broiler chickens offered wheat-based diets
Published in Animal feed science and technology (01-12-2019)“…•500 FTU/kg phytase increased weight gain by 8.39% (1485 versus 1370 g/bird).•Also improved FCR by 5.10% (1.397 versus 1.472) from 7 to 28 days post-hatch.•And…”
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