Search Results - "McPhillips, Kathleen A."

Cell-Surface Calreticulin Initiates Clearance of Viable or Apoptotic Cells through trans-Activation of LRP on the Phagocyte by Gardai, Shyra J., McPhillips, Kathleen A., Frasch, S. Courtney, Janssen, William J., Starefeldt, Anna, Murphy-Ullrich, Joanne E., Bratton, Donna L., Oldenborg, Per-Arne, Michalak, Marek, Henson, Peter M.

“…Apoptotic-cell removal is critical for development, tissue homeostasis, and resolution of inflammation. Although many candidate systems exist, only…”
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Surfactant Proteins A and D Suppress Alveolar Macrophage Phagocytosis via Interaction with SIRPα by JANSSEN, William J, MCPHILLIPS, Kathleen A, DICKINSON, Matthew G, LINDERMAN, Derek J, MORIMOTO, Konosuke, YI QUN XIAO, OLDHAM, Kelly M, VANDIVIER, R. William, HENSON, Peter M, GARDAI, Shyra J

“…Efficient removal of apoptotic cells is essential for the resolution of acute pulmonary inflammation. Alveolar macrophages ingest apoptotic cells less avidly…”
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Lovastatin Enhances Clearance of Apoptotic Cells (Efferocytosis) with Implications for Chronic Obstructive Pulmonary Disease by Morimoto, Konosuke, Janssen, William J, Fessler, Michael B, McPhillips, Kathleen A, Borges, Valeria M, Bowler, Russell P, Xiao, Yi-Qun, Kench, Jennifer A, Henson, Peter M, Vandivier, R. William

“…Statins are potent, cholesterol-lowering agents with newly appreciated, broad anti-inflammatory properties, largely based upon their ability to block the…”
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Impaired phagocytosis of apoptotic cells by macrophages in chronic granulomatous disease is reversed by IFN-γ in a nitric oxide-dependent manner by Fernandez-Boyanapalli, Ruby, McPhillips, Kathleen A, Frasch, S Courtney, Janssen, William J, Dinauer, Mary C, Riches, David W H, Henson, Peter M, Byrne, Aideen, Bratton, Donna L

“…Immunodeficiency in chronic granulomatous disease (CGD) is well characterized. Less understood are exaggerated sterile inflammation and autoimmunity associated…”
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Assessment of apoptotic cell phagocytosis by macrophages by McPhillips, Kathleen A, Erwig, Lars-Peter

“…Cells undergo apoptosis during development, tissue homeostasis, and disease, and are rapidly cleared by both professional and nonprofessional phagocytes. In…”
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Impaired Phagocytosis of Apoptotic Cells by Macrophages in Chronic Granulomatous Disease Is Reversed by IFN-g in a Nitric Oxide-Dependent Manner by Fernandez-Boyanapalli, Ruby, McPhillips, Kathleen A, Frasch, SCourtney, Janssen, William J, Dinauer, Mary C, Riches, David WH, Henson, Peter M, Byrne, Aideen, Bratton, Donna L

“…Immunodeficiency in chronic granulomatous disease (CGD) is well characterized. Less understood are exaggerated sterile inflammation and autoimmunity associated…”
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Statins enhance clearance of apoptotic cells through modulation of Rho-GTPases by Morimoto, Konosuke, Janssen, William J, Fessler, Michael B, Xiao, Yi Qun, McPhillips, Kathleen A, Borges, Valeria M, Kench, Jennifer A, Henson, Peter M, Vandivier, R William

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Surfactant Proteins A and D Suppress Alveolar Macrophage Phagocytosis via Interaction with SIRP{alpha} by Janssen, William J, McPhillips, Kathleen A, Dickinson, Matthew G, Linderman, Derek J, Morimoto, Konosuke, Xiao, Yi Qun, Oldham, Kelly M, Vandivier, R. William, Henson, Peter M, Gardai, Shyra J

“…Efficient removal of apoptotic cells is essential for the resolution of acute pulmonary inflammation. Alveolar macrophages ingest apoptotic cells less avidly…”
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TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation by Borges, Valeria M, Vandivier, R William, McPhillips, Kathleen A, Kench, Jennifer A, Morimoto, Konosuke, Groshong, Steve D, Richens, Tiffany R, Graham, Brian B, Muldrow, Alaina M, Van Heule, Lea, Henson, Peter M, Janssen, William J

“…Efficient removal of apoptotic cells is essential for resolution of inflammation. Failure to clear dying cells can exacerbate lung injury and lead to…”
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