Search Results - "McPhie, Gordon I"

Identification and pharmacological profile of a new class of selective nicotinic acetylcholine receptor potentiators by Broad, Lisa M, Zwart, Ruud, Pearson, Kathy H, Lee, Martin, Wallace, Louise, McPhie, Gordon I, Emkey, Renee, Hollinshead, Sean P, Dell, Colin P, Baker, S Richard, Sher, Emanuele

“…Here we report the discovery, by high-throughput screening, of three novel (2-amino-5-keto)thiazole compounds that act as selective potentiators of nicotinic…”
Get more information

Expression and functional characterisation of a human chimeric nicotinic receptor with α6β4 properties by Evans, Non M., Bose, Suchira, Benedetti, Giovanni, Zwart, Ruud, Pearson, Kathy H., McPhie, Gordon I., Craig, Peter J., Benton, Jason P., Volsen, Stephen G., Sher, Emanuele, Broad, Lisa M.

“…Despite being cloned several years ago, the expression of functional nicotinic acetylcholine receptors containing the human α6 subunit in recombinant mammalian…”
Get full text

PSAB-OFP, a selective α7 nicotinic receptor agonist, is also a potent agonist of the 5-HT3 receptor by BROAD, Lisa M, FELTHOUSE, Catherine, BAKER, S. Richard, SHER, Emanuele, ZWART, Ruud, MCPHIE, Gordon I, PEARSON, Kathy H, CRAIG, Peter J, WALLACE, Louise, BROADMORE, Richard J, BOOT, John R, KEENAN, Martine

Get full text

Stable expression and characterisation of a human α7 nicotinic subunit chimera: a tool for functional high-throughput screening by Craig, Peter J., Bose, Suchira, Zwart, Ruud, Beattie, Ruth E., Folly, Elizabeth A., Johnson, Laura R., Bell, Emma, Evans, Non M., Benedetti, Giovanni, Pearson, Kathy H., McPhie, Gordon I., Volsen, Stephen G., Millar, Neil S., Sher, Emanuele, Broad, Lisa M.

“…A chimera comprising the N-terminal region of the human α7 nicotinic acetylcholine receptor, fused to the transmembrane/C-terminal domains of the mouse…”
Get full text

PSAB-OFP, a selective alpha 7 nicotinic receptor agonist, is also a potent agonist of the 5-HT3 receptor by Broad, Lisa M, Felthouse, Catherine, Zwart, Ruud, McPhie, Gordon I, Pearson, Kathy H, Craig, Peter J, Wallace, Louise, Broadmore, Richard J, Boot, John R, Keenan, Martine, Baker, S Richard, Sher, Emanuele

“…5-Hydroxytryptamine 3 (5-HT(3)) and alpha 7 nicotinic receptors share high sequence homology and pharmacological cross-reactivity. An assessment of the…”
Get full text

Stable expression and characterisation of a human alpha 7 nicotinic subunit chimera: a tool for functional high-throughput screening by Craig, Peter J, Bose, Suchira, Zwart, Ruud, Beattie, Ruth E, Folly, Elizabeth A, Johnson, Laura R, Bell, Emma, Evans, Non M, Benedetti, Giovanni, Pearson, Kathy H, McPhie, Gordon I, Volsen, Stephen G, Millar, Neil S, Sher, Emanuele, Broad, Lisa M

“…A chimera comprising the N-terminal region of the human alpha7 nicotinic acetylcholine receptor, fused to the transmembrane/C-terminal domains of the mouse…”
Get full text

Expression and functional characterisation of a human chimeric nicotinic receptor with alpha6beta4 properties by Evans, Non M, Bose, Suchira, Benedetti, Giovanni, Zwart, Ruud, Pearson, Kathy H, McPhie, Gordon I, Craig, Peter J, Benton, Jason P, Volsen, Stephen G, Sher, Emanuele, Broad, Lisa M

“…Despite being cloned several years ago, the expression of functional nicotinic acetylcholine receptors containing the human alpha6 subunit in recombinant…”
Get full text

PSAB-OFP, a selective α7 nicotinic receptor agonist, is also a potent agonist of the 5-HT 3 receptor by Broad, Lisa M, Felthouse, Catherine, Zwart, Ruud, McPhie, Gordon I, Pearson, Kathy H, Craig, Peter J, Wallace, Louise, Broadmore, Richard J, Boot, John R, Keenan, Martine, Baker, S.Richard, Sher, Emanuele

“…5-Hydroxytryptamine 3 (5-HT 3) and α7 nicotinic receptors share high sequence homology and pharmacological cross-reactivity. An assessment of the potential…”
Get full text