Search Results - "McPherson, Ann J"

Immune regulation by 4-1BB and 4-1BBL: complexities and challenges by Wang, Chao, Lin, Gloria H.Y, McPherson, Ann J, Watts, Tania H

“…The tumor necrosis factor receptor family member 4-1BB plays a key role in the survival of activated and memory CD8⁺ T cells. Depending on the disease model,…”
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Opposing Roles for TRAF1 in the Alternative versus Classical NF-κB Pathway in T Cells by McPherson, Ann J., Snell, Laura M., Mak, Tak W., Watts, Tania H.

“…T cells lacking TRAF1 hyperproliferate in response to T cell receptor signaling but have impaired signaling downstream of specific TNFR family members such as…”
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The contextual role of TNFR family members in CD8+ T-cell control of viral infections by Wortzman, Michael E., Clouthier, Derek L., McPherson, Ann J., Lin, Gloria H. Y., Watts, Tania H.

“…Summary Immunity to viruses must be tightly controlled to avoid pathology. Receptors and ligands of the tumor necrosis factor (TNF) family play important roles…”
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T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy by Snell, Laura M., Lin, Gloria H. Y., McPherson, Ann J., Moraes, Theo J., Watts, Tania H.

“…GITR [glucocorticoid inducible tumor necrosis factor receptor (TNFR)‐related protein] and 4‐1BB are costimulatory TNFR family members that are expressed on…”
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CD8 T cell-intrinsic GITR is required for T cell clonal expansion and mouse survival following severe influenza infection by Snell, Laura M, McPherson, Ann J, Lin, Gloria H Y, Sakaguchi, Shimon, Pandolfi, Pier Paolo, Riccardi, Carlo, Watts, Tania H

“…The regulation of T cell expansion by TNFR family members plays an important role in determining the magnitude of the immune response to pathogens. As several…”
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Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection by Wang, Chao, McPherson, Ann J, Jones, R Brad, Kawamura, Kim S, Lin, Gloria H Y, Lang, Philipp A, Ambagala, Thanuja, Pellegrini, Marc, Calzascia, Thomas, Aidarus, Nasra, Elford, Alisha R, Yue, Feng Yun, Kremmer, Elisabeth, Kovacs, Colin M, Benko, Erika, Tremblay, Cecile, Routy, Jean-Pierre, Bernard, Nicole F, Ostrowski, Mario A, Ohashi, Pamela S, Watts, Tania H

“…The signaling adaptor TNFR-associated factor 1 (TRAF1) is specifically lost from virus-specific CD8 T cells during the chronic phase of infection with HIV in…”
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Role of 4-1BBL and TRAF1 in the CD8 T cell response to influenza virus and HIV by Watts, Tania H, Lin, Gloria H Y, Wang, Chao, McPherson, Ann J, Snell, Laura M, Sabbagh, Laurent

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The contextual role of TNFR family members in CD 8 + T‐cell control of viral infections by Wortzman, Michael E., Clouthier, Derek L., McPherson, Ann J., Lin, Gloria H. Y., Watts, Tania H.

“…Summary Immunity to viruses must be tightly controlled to avoid pathology. Receptors and ligands of the tumor necrosis factor ( TNF ) family play important…”
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T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy: TNF Receptor Family Members by SNELL, Laura M, LIN, Gloria H. Y, MCPHERSON, Ann J, MORAES, Theo J, WATTS, Tania H

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Immune regulation by 4-1 BB and 4-1BBL: complexities and challenges: Mechanisms of Costimulation by CHAO WANG, LIN, Gloria H. Y, MCPHERSON, Ann J, WATTS, Tania H

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