Search Results - "McPartland, John M"

Cannabis in Asia: its center of origin and early cultivation, based on a synthesis of subfossil pollen and archaeobotanical studies by McPartland, John M., Hegman, William, Long, Tengwen

“…Biogeographers assign the Cannabis centre of origin to “Central Asia”, mostly based on wild-type plant distribution data. We sought greater precision by adding…”
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Care and feeding of the endocannabinoid system: a systematic review of potential clinical interventions that upregulate the endocannabinoid system by McPartland, John M, Guy, Geoffrey W, Di Marzo, Vincenzo

“…The "classic" endocannabinoid (eCB) system includes the cannabinoid receptors CB1 and CB2, the eCB ligands anandamide (AEA) and 2-arachidonoylglycerol (2-AG),…”
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A classification of endangered high-THC cannabis (Cannabis sativa subsp. indica) domesticates and their wild relatives by McPartland, John M, Small, Ernest

“…Two kinds of drug-type gained layman's terms in the 1980s. "Sativa" had origins in South Asia (India), with early historical dissemination to Southeast Asia,…”
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Evolutionary origins of the endocannabinoid system by McPartland, John M., Matias, Isabel, Di Marzo, Vincenzo, Glass, Michelle

“…Endocannabinoid system evolution was estimated by searching for functional orthologs in the genomes of twelve phylogenetically diverse organisms: Homo sapiens,…”
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Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review by McPartland, John M, Duncan, Marnie, Di Marzo, Vincenzo, Pertwee, Roger G

“…Based upon evidence that the therapeutic properties of Cannabis preparations are not solely dependent upon the presence of Δ(9) -tetrahydrocannabinol (THC),…”
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Experimental Endozoochory of Cannabis sativa Achenes by McPartland, John M., Naraine, Steve G.

“…The mechanism by which Cannabis sativa dispersed from its center of origin remains an open question. The literature provides many hypotheses, which we review…”
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Obesity, the endocannabinoid system, and bias arising from pharmaceutical sponsorship by McPartland, John M

“…Previous research has shown that academic physicians conflicted by funding from the pharmaceutical industry have corrupted evidence based medicine and helped…”
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Expression of the endocannabinoid system in fibroblasts and myofascial tissues by McPartland, John M., M.S., D.O

“…Summary The endocannabinoid (eCB) system, like the better-known endorphin system, consists of cell membrane receptors, endogenous ligands and…”
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Cannabis utilization and diffusion patterns in prehistoric Europe: a critical analysis of archaeological evidence by McPartland, John M., Hegman, William

“…Archaeological evidence of Cannabis sativa is comprised of textiles, cordage, fibre and seeds, or pottery impressions of those materials, as well as…”
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Models of Cannabis Taxonomy, Cultural Bias, and Conflicts between Scientific and Vernacular Names by McPartland, John M., Guy, Geoffrey W.

“…Debates over Cannabis sativa L. and C. indica Lam. center on their taxonomic circumscription and rank. This perennial puzzle has been compounded by the viral…”
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Cannabis is indigenous to Europe and cultivation began during the Copper or Bronze age: a probabilistic synthesis of fossil pollen studies by McPartland, John M., Guy, Geoffrey W., Hegman, William

“…Conventional wisdom states Cannabis sativa originated in Asia and its dispersal to Europe depended upon human transport. Various Neolithic or Bronze age groups…”
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Functional mapping of cannabinoid receptor homologs in mammals, other vertebrates, and invertebrates by McPartland, John M., Glass, Michelle

“…Over the past decade, several putative homologs of cannabinoid receptors (CBRs) have been identified by homology screening. Homology screening utilizes…”
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Origins of Cannabis sativa in Ireland and the Concept of Celtic Hemp: An Interdisciplinary Review by McPartland, John M, O'Sullivan, Saoirse E

“…Ireland's agriculture has been shaped by Celts, Romano-British Christians, Norse-Vikings, Anglo-Normans, and subsequent migrants. Who introduced hemp ( ) to…”
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Investigation of non-CB1, non-CB2 WIN55212-2-sensitive G-protein-coupled receptors in the brains of mammals, birds, and amphibians by Breivogel, Chris S., McPartland, John M., Parekh, Bhavita

“…Purpose: Previous studies have found non-CB 1 non-CB 2 G-protein-coupled receptors in rodents that are activated by the aminoalkylindole cannabinoid agonist…”
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Phylogenomic and chemotaxonomic analysis of the endocannabinoid system by McPartland, John M

“…The endocannabinoid system consists of two cannabinoid (CB) receptors, seven ligands, and ligand-catabolizing enzymes such as fatty acid amid hydrolase (FAAH)…”
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Investigation of non-CB 1 , non-CB 2 WIN55212-2-sensitive G-protein-coupled receptors in the brains of mammals, birds, and amphibians by Breivogel, Chris S, McPartland, John M, Parekh, Bhavita

“…Previous studies have found non-CB non-CB G-protein-coupled receptors in rodents that are activated by the aminoalkylindole cannabinoid agonist WIN55212-2…”
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The diagnosis of fibromyalgia in women may be influenced by menstrual cycle phase by Dunnett, Alenka J., M.Ost, Roy, Dianne, R.N., Ph.D, Stewart, Andrew, Ph.D, McPartland, John M., D.O., M.S

“…Summary This investigation evaluated changes in pressure pain threshold (PPT) in 11 healthy females during three phases of the menstrual cycle: menstrual (day…”
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Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists by Ashton, John C, Wright, Jason L, McPartland, John M, Tyndall, Joel D A

“…Cannabinoids in current use such as nabilone activate both CB1 and CB2 receptors. Selective CB2 activation may provide some of the therapeutic effects of…”
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Cannabis, cannabinoids and reproduction by Park, Boram, McPartland, John M., Glass, Michelle

“…In most countries Cannabis is the most widely used illegal drug. Its use during pregnancy in developed nations is estimated to be approximately 10%. Recent…”
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The endocannabinoid system: an osteopathic perspective by McPartland, John M

“…The present review provides an update on endocannabinoid basic science and clinical studies and proposes a new model to describe reciprocal interactions…”
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