Search Results - "McNulty, M"

Preclinical characterization of abemaciclib in hormone receptor positive breast cancer by Torres-Guzmán, Raquel, Calsina, Bruna, Hermoso, Ana, Baquero, Carmen, Alvarez, Beatriz, Amat, Joaquín, McNulty, Ann M, Gong, Xueqian, Boehnke, Karsten, Du, Jian, de Dios, Alfonso, Beckmann, Richard P, Buchanan, Sean, Lallena, María José

“…Abemaciclib is an ATP-competitive, reversible kinase inhibitor selective for CDK4 and CDK6 that has shown antitumor activity as a single agent in hormone…”
Get full text

RNA-dependent stabilization of SUV39H1 at constitutive heterochromatin by Johnson, Whitney L, Yewdell, William T, Bell, Jason C, McNulty, Shannon M, Duda, Zachary, O'Neill, Rachel J, Sullivan, Beth A, Straight, Aaron F

“…Heterochromatin formed by the SUV39 histone methyltransferases represses transcription from repetitive DNA sequences and ensures genomic stability. How SUV39…”
Get full text

A genetic memory initiates the epigenetic loop necessary to preserve centromere position by Hoffmann, Sebastian, Izquierdo, Helena M, Gamba, Riccardo, Chardon, Florian, Dumont, Marie, Keizer, Veer, Hervé, Solène, McNulty, Shannon M, Sullivan, Beth A, Manel, Nicolas, Fachinetti, Daniele

“…Centromeres are built on repetitive DNA sequences (CenDNA) and a specific chromatin enriched with the histone H3 variant CENP‐A, the epigenetic mark that…”
Get full text

Third-line re-treatment of advanced pancreatic adenocarcinoma with gemcitabine and nab-paclitaxel by Das, A., Dean, A., McNulty, M.

Get full text

Use of gemcitabine and nab-paclitaxel as a third-line treatment following failure of first line gemcitabine for advanced pancreatic adenocarcinoma by McNulty, M., Dean, A., Das, A., Gordon, M.

Get full text

Alpha satellite DNA biology: finding function in the recesses of the genome by McNulty, Shannon M., Sullivan, Beth A.

Get full text

Don't wear me out—the public's knowledge of and attitudes to antibiotic use by McNulty, Cliodna A. M., Boyle, Paul, Nichols, Tom, Clappison, Peter, Davey, Peter

“…Objectives To assess the public's knowledge and attitudes to antibiotics, their reported antibiotic use and the relationship between them. Patients and methods…”
Get full text

Comparative analysis of functional assay evidence use by ClinGen Variant Curation Expert Panels by Kanavy, Dona M, McNulty, Shannon M, Jairath, Meera K, Brnich, Sarah E, Bizon, Chris, Powell, Bradford C, Berg, Jonathan S

“…The 2015 American College of Medical Genetics and Genomics (ACMG) and the Association for Molecular Pathology (AMP) guidelines for clinical sequence variant…”
Get full text

Therapeutic Inhibition of MAP Kinase Interacting Kinase Blocks Eukaryotic Initiation Factor 4E Phosphorylation and Suppresses Outgrowth of Experimental Lung Metastases by KONICEK, Bruce W, STEPHENS, Jennifer R, MCCANN, Denis J, PELLETIER, Jerry, FURIC, Luc, YINGLING, Jonathan M, STANCATO, Louis F, SONENBERG, Nahum, GRAFF, Jeremy R, MCNULTY, Ann M, ROBICHAUD, Nathaniel, PEERY, Robert B, DUMSTORF, Chad A, DOWLESS, Michele S, IVERSEN, Philip W, PARSONS, Stephen, ELLIS, Karen E

“…Activation of the translation initiation factor 4E (eIF4E) promotes malignant transformation and metastasis. Signaling through the AKT-mTOR pathway activates…”
Get full text

Comparing public knowledge around value of hand and respiratory hygiene, vaccination, and pre- and post-national COVID-19 lockdown in England by Read, Brieze, McNulty, Cliodna A.M., Verlander, Neville Q., Moss, Nicola, Lecky, Donna M.

“…The COVID-19 pandemic spotlighted the importance of infection prevention and control (IPC) measures. Existing literature focuses on healthcare professionals,…”
Get full text

CTX-M ESBL-producing Enterobacteriaceae: estimated prevalence in adults in England in 2014 by McNulty, Cliodna A M, Lecky, Donna M, Xu-McCrae, Li, Nakiboneka-Ssenabulya, Deborah, Chung, Keun-Taik, Nichols, Tom, Thomas, Helen Lucy, Thomas, Mike, Alvarez-Buylla, Adela, Turner, Kim, Shabir, Sahida, Manzoor, Susan, Smith, Stephen, Crocker, Linda, Hawkey, Peter M

“…ESBL-producing Enterobacteriaceae (ESBLPE) are increasing in prevalence worldwide and are more difficult to treat than non-ESBLPE. Their prevalence in the UK…”
Get full text

The cohesin subunit Rad21 is a negative regulator of hematopoietic self-renewal through epigenetic repression of Hoxa7 and Hoxa9 by Fisher, J B, Peterson, J, Reimer, M, Stelloh, C, Pulakanti, K, Gerbec, Z J, Abel, A M, Strouse, J M, Strouse, C, McNulty, M, Malarkannan, S, Crispino, J D, Milanovich, S, Rao, S

“…Acute myelogenous leukemia (AML) is a high-risk hematopoietic malignancy caused by a variety of mutations, including genes encoding the cohesin complex. Recent…”
Get full text

Effect of availability of HIV self-testing on HIV testing frequency in gay and bisexual men at high risk of infection (FORTH): a waiting-list randomised controlled trial by Jamil, Muhammad S, MPH, Prestage, Garrett, PhD, Fairley, Christopher K, Prof, Grulich, Andrew E, Prof, Smith, Kirsty S, MPH, Chen, Marcus, PhD, Holt, Martin, PhD, McNulty, Anna M, MMed, Bavinton, Benjamin R, PhD, Conway, Damian P, PhD, Wand, Handan, PhD, Keen, Phillip, BA, Bradley, Jack, Kolstee, Johann, MPH, Batrouney, Colin, BA, Russell, Darren, PhD, Law, Matthew, Prof, Kaldor, John M, Prof, Guy, Rebecca J, Dr

“…Summary Background Frequent testing of individuals at high risk of HIV is central to current prevention strategies. We aimed to determine if HIV self-testing…”
Get full text

Preventive Intervention for Living Donor Psychosocial Outcomes: Feasibility and Efficacy in a Randomized Controlled Trial by Dew, M. A., DiMartini, A. F., DeVito Dabbs, A. J., Zuckoff, A., Tan, H. P., McNulty, M. L., Switzer, G. E., Fox, K. R., Greenhouse, J. B., Humar, A.

“…There are no evidence‐based interventions to prevent adverse psychosocial consequences after living donation. We conducted a single‐site randomized controlled…”
Get full text

Cytokine Gene Expression in Peripheral Blood Mononuclear Cells and Tissues of Cattle Infected with Mycobacterium avium subsp. paratuberculosis: Evidence for an Inherent Proinflammatory Gene Expression Pattern by COUSSENS, Paul M, VERMAN, Nitin, COUSSENS, Marc A, ELFTMAN, Michael D, MCNULTY, Amanda M

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
Get full text

European Antibiotic Awareness Day 2012: general practitioners encouraged to TARGET antibiotics through guidance, education and tools by MCNULTY, Cliodna A. M

“…On 18 November 2012, the UK will once again support the annual European Antibiotic Awareness Day (EAAD). In particular, hospitals will be asked to promote the…”
Get full text

Is Sugar Consumption Detrimental to Health? A Review of the Evidence 1995—2006 by Ruxton, C.H.S, Gardner, E.J, McNulty, H.M

“…Many countries set quantitative targets for added sugars, justifying this by expressing concern about the likely impact of sugar on weight control, dental…”
Get full text

The English antibiotic awareness campaigns: did they change the public's knowledge of and attitudes to antibiotic use? by McNulty, Cliodna A. M., Nichols, Tom, Boyle, Paul J., Woodhead, Mark, Davey, Peter

“…Objectives To determine the effect of the 2008 English public antibiotic campaigns. Methods English and Scottish (acting as controls) adults aged ≥15 years…”
Get full text

Histopathology of naturally occurring and surgically induced osteoarthritis in mice by McNulty, M.A, Loeser, R.F, Davey, C, Callahan, M.F, Ferguson, C.M, Carlson, C.S

“…Summary Objective The morphology of lesions in mouse models of osteoarthritis (OA) has not been comprehensively characterized, in part because current…”
Get full text

Sustaining success: a qualitative study of gay and bisexual men's experiences and perceptions of HIV self-testing in a randomized controlled trial by Zhang, Ye, Guy, Rebecca J, Smith, Kirsty S, Jamil, Muhammad S, Prestage, Garrett, Applegate, Tanya L, Conway, Damian P, Holt, Martin, Keen, Phillip, Bavinton, Benjamin, McNulty, Anna M, Batrouney, Colin, Russell, Darren, Vaughan, Matthew, Chen, Marcus, Fairley, Christopher K, Grulich, Andrew E, Kaldor, John M, Callander, Denton

“…HIV self-testing was proved as an effective tool for increasing testing frequency in gay and bisexual men at high risk of infection. Questions remain about…”
Get full text