Search Results - "McNulty, E."
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Hydrophilic Interaction Chromatography Reduces the Complexity of the Phosphoproteome and Improves Global Phosphopeptide Isolation and Detection
Published in Molecular & cellular proteomics (01-05-2008)“…The diversity and complexity of proteins and peptides in biological systems requires powerful liquid chromatography-based separations to optimize resolution…”
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Turning Out to Vote: The Costs of Finding and Getting to the Polling Place
Published in The American political science review (01-02-2011)“…Could changing the locations of polling places affect the outcome of an election by increasing the costs of voting for some and decreasing them for others? The…”
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Temporal Characterization of Prion Shedding in Secreta of White-Tailed Deer in Longitudinal Study of Chronic Wasting Disease, United States
Published in Emerging infectious diseases (01-10-2024)“…Chronic wasting disease (CWD) affects cervids in North America, Asia, and Scandinavia. CWD is unique in its efficient spread, partially because of contact with…”
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Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction
Published in Nature chemical biology (01-03-2014)“…Allosteric small-molecule inhibitors of the p53-induced oncogenic phosphatase Wip1 bind at a ‘flap’ subdomain near the catalytic site. Inhibitor GSK2830371…”
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Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
Published in The New England journal of medicine (20-01-2005)“…This placebo-controlled study compared the effect of amiodarone and an implantable cardioverter–defibrillator (ICD) on mortality in patients with New York…”
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Monitoring longitudinal immunological responses to bluetongue virus 17 in experimentally infected sheep
Published in Virus research (01-12-2023)“…•BTV-17 infection in sheep showed sustained viral RNA detection.•Infectious virus detection diminished during height of immune response.•BTV-17 causes…”
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Very low oral exposure to prions of brain or saliva origin can transmit chronic wasting disease
Published in PloS one (20-08-2020)“…The minimum infectious dose required to induce CWD infection in cervids remains unknown, as does whether peripherally shed prions and/or multiple low dose…”
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In vitro and in vivo induction of fetal hemoglobin with a reversible and selective DNMT1 inhibitor
Published in Haematologica (Roma) (01-07-2021)“…Pharmacological induction of fetal hemoglobin (HbF) expression is an effective therapeutic strategy for the management of beta-hemoglobinopathies such as…”
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Differential Roles for "Nr4a1" and "Nr4a2" in Object Location vs. Object Recognition Long-Term Memory
Published in Learning & memory (Cold Spring Harbor, N.Y.) (01-12-2012)“…"Nr4a1" and "Nr4a2" are transcription factors and immediate early genes belonging to the nuclear receptor Nr4a family. In this study, we examine their role in…”
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Progression of chronic wasting disease in white-tailed deer analyzed by serial biopsy RT-QuIC and immunohistochemistry
Published in PloS one (14-02-2020)“…Chronic wasting disease (CWD) continues to spread or be recognized in the United States, Canada, and Europe. CWD is diagnosed by demonstration of the causative…”
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MAPK Scaffold IQGAP1 Binds the EGF Receptor and Modulates Its Activation
Published in The Journal of biological chemistry (29-04-2011)“…Cellular responses produced by EGF are mediated through the receptor (EGFR) and by various enzymes and scaffolds. Recent studies document IQGAP1 as a scaffold…”
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Characterization of subclinical ZIKV infection in immune-competent guinea pigs and mice
Published in Journal of general virology (26-08-2021)“…An infectious agent’s pathogenic and transmission potential is heavily influenced by early events during the asymptomatic or subclinical phase of disease…”
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Plant lectin can target receptors containing sialic acid, exemplified by podoplanin, to inhibit transformed cell growth and migration
Published in PloS one (23-07-2012)“…Cancer is a leading cause of death of men and women worldwide. Tumor cell motility contributes to metastatic invasion that causes the vast majority of cancer…”
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Expression of the cellular prion protein by mast cells in white-tailed deer carotid body, cervical lymph nodes and ganglia
Published in Prion (01-12-2024)“…Chronic wasting disease (CWD) is a transmissible and fatal prion disease that affects cervids. While both oral and nasal routes of exposure to prions cause…”
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Detection of Chronic Wasting Disease Prions in Fetal Tissues of Free-Ranging White-Tailed Deer
Published in Viruses (03-12-2021)“…The transmission of chronic wasting disease (CWD) has largely been attributed to contact with infectious prions shed in excretions (saliva, urine, feces,…”
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Immunological and Pathogenic Differences of Two Experimental Bluetongue Virus Serotype Infections Evaluated in Two Disparate Host Species
Published in Viruses (10-10-2024)“…Bluetongue virus (BTV) is a prevalent midge-borne pathogen that infects ruminant species worldwide. BTV infections range from asymptomatic to lethal, with…”
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Crisis leadership: a case for inclusion in accredited Master of Public Health program curricula
Published in Public health (London) (01-08-2022)“…To evaluate the exposure to crisis leadership theory already present in Council on Education for Public Health (CEPH) accredited Master of Public Health (MPH)…”
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Left Atrial Structure and Function in Heart Failure with Preserved Ejection Fraction: A RELAX Substudy
Published in PloS one (03-11-2016)“…Given the emerging recognition of left atrial structure and function as an important marker of disease in heart failure with preserved ejection fraction…”
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Evaluation of a provocative dyspnea severity score in acute heart failure
Published in The American heart journal (01-02-2016)“…Background The acute heart failure (AHF) Syndromes International Working Group proposed that dyspnea be assessed under standardized, incrementally provocative…”
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