Search Results - "McNerney, Christina"
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R-loop induced G-quadruplex in non-template promotes transcription by successive R-loop formation
Published in Nature communications (07-07-2020)“…G-quadruplex (G4) is a noncanonical secondary structure of DNA or RNA which can enhance or repress gene expression, yet the underlying molecular mechanism…”
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Thyroid hormone signaling specifies cone photoreceptor subtypes during eye development: Insights from model organisms and human stem cell-derived retinal organoids
Published in Vitamins and hormones (2021)“…Cones are the color-detecting photoreceptors of the vertebrate eye. Cones are specialized into subtypes whose functions are determined by the expression of…”
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Fluorescence-Detected Conformational Changes in Duplex DNA in Open Complex Formation by Escherichia coli RNA Polymerase: Upstream Wrapping and Downstream Bending Precede Clamp Opening and Insertion of the Downstream Duplex
Published in Biochemistry (Easton) (28-04-2020)“…FRET (fluorescence resonance energy transfer) between far-upstream (−100) and downstream (+14) cyanine dyes (Cy3, Cy5) showed extensive bending and wrapping of…”
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G-Quadruplex and Protein Binding by Single-Molecule FRET Microscopy
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2019)“…G-quadruplex (G4) is a non-canonical nucleic acid structure that arises from the stacking of planar G-tetrads, stabilized by monovalent cations. G4 forming…”
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G-Quadruplex Forming Sequence Modulated Transcription
Published in Biophysical journal (15-02-2019)Get full text
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Roles of Upstream Promoter DNA in Bacterial Transcription Initiation
Published in Biophysical journal (02-02-2018)Get full text
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Bending and Wrapping of Upstream Promoter DNA on E. coli RNA Polymerase Facilitates Open Complex Formation in Transcription Initiation; A Fluorescence (FRET, PIFE) Study
Published in The FASEB journal (01-04-2018)“…Removal of the far‐upstream region of promoter DNA reduces the isomerization rate of closed complexes (CC) to open complexes (OC) of Escherichia coli RNA…”
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Fluorescence Kinetic Studies of DNA Unwrapping in Transcription Initiation with NTP addition and in Open Complex Dissociation by high salt
Published in The FASEB journal (01-04-2018)“…λPR promoter DNA is bent and wrapped around E. coli RNA polymerase (RNAP) in the stable open complex (RPo), as demonstrated by Cy3‐Cy5 fluorescent energy…”
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Fluorescence-Detected Conformational Changes in Duplex DNA in Open Complex Formation by E. coli RNA Polymerase: Upstream Wrapping and Downstream Bending Precede Clamp Opening and Insertion of the Downstream Duplex
Published in Biochemistry (Easton) (07-04-2020)“…FRET (fluorescence resonance energy transfer) between far-upstream(−100) and downstream(+14) cyanine dyes showed extensive bending/wrapping of λP R promoter…”
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