Search Results - "McNeill, Helen"

Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation by McNeill, Helen, Reginensi, Antoine

“…In the kidney, formation of the functional filtration units, the nephrons, is essential for postnatal life. During development, mesenchymal progenitors tightly…”
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Hippo gains weight: added insights and complexity to pathway control by Enderle, Leonie, McNeill, Helen

“…The Hippo pathway is a kinase cascade, formed by Hippo, Salvador, Warts, and Mats, that regulates the subcellular distribution and transcriptional activity of…”
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Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity by Saburi, Sakura, Hester, Ian, Goodrich, Lisa, McNeill, Helen

“…The atypical cadherin fat (ft) was originally discovered as a tumor suppressor in Drosophila and later shown to regulate a form of tissue patterning known as…”
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Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development by Reginensi, Antoine, Scott, Rizaldy P, Gregorieff, Alex, Bagherie-Lachidan, Mazdak, Chung, Chaeuk, Lim, Dae-Sik, Pawson, Tony, Wrana, Jeff, McNeill, Helen

“…Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis downstream of the Hippo kinase pathway. We investigated Yap function…”
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The inner nuclear membrane protein NEMP1 supports nuclear envelope openings and enucleation of erythroblasts by Hodzic, Didier, Wu, Jun, Krchma, Karen, Jurisicova, Andrea, Tsatskis, Yonit, Liu, Yijie, Ji, Peng, Choi, Kyunghee, McNeill, Helen

“…Nuclear envelope membrane proteins (NEMPs) are a conserved family of nuclear envelope (NE) proteins that reside within the inner nuclear membrane (INM). Even…”
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Regulation of long-range planar cell polarity by Fat-Dachsous signaling by Sharma, Praveer, McNeill, Helen

“…Fat (Ft) and Dachsous (Ds) are large cadherins that bind each other and have conserved roles in regulating planar cell polarity (PCP). We quantitatively…”
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Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow by Betterman, Kelly L, Sutton, Drew L, Secker, Genevieve A, Kazenwadel, Jan, Oszmiana, Anna, Lim, Lillian, Miura, Naoyuki, Sorokin, Lydia, Hogan, Benjamin M, Kahn, Mark L, McNeill, Helen, Harvey, Natasha L

“…The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The…”
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Mechanical stability of the cell nucleus - roles played by the cytoskeleton in nuclear deformation and strain recovery by Wang, Xian, Liu, Haijiao, Zhu, Min, Cao, Changhong, Xu, Zhensong, Tsatskis, Yonit, Lau, Kimberly, Kuok, Chikin, Filleter, Tobin, McNeill, Helen, Simmons, Craig A, Hopyan, Sevan, Sun, Yu

“…Extracellular forces transmitted through the cytoskeleton can deform the cell nucleus. Large nuclear deformations increase the risk of disrupting the integrity…”
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Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease by McNeill, Helen, Saburi, Sakura, Hester, Ian, Fischer, Evelyne, Pontoglio, Marco, Eremina, Vera, Gessler, Manfred, Quaggin, Sue E, Harrison, Robert, Mount, Richard

“…Tissue organization in Drosophila is regulated by the core planar cell polarity (PCP) proteins Frizzled, Dishevelled, Prickle, Van Gogh and Flamingo. Core PCP…”
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Podocyte-Specific Deletion of Yes-Associated Protein Causes FSGS and Progressive Renal Failure by Schwartzman, Monica, Reginensi, Antoine, Wong, Jenny S, Basgen, John M, Meliambro, Kristin, Nicholas, Susanne B, D'Agati, Vivette, McNeill, Helen, Campbell, Kirk N

“…FSGS is the most common primary glomerular disease underlying ESRD in the United States and is increasing in incidence globally. FSGS results from podocyte…”
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A critical role for NF2 and the Hippo pathway in branching morphogenesis by Reginensi, Antoine, Enderle, Leonie, Gregorieff, Alex, Johnson, Randy L., Wrana, Jeffrey L., McNeill, Helen

“…Branching morphogenesis is a complex biological process common to the development of most epithelial organs. Here we demonstrate that NF2, LATS1/2 and YAP play…”
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Yap and Taz are required for Ret-dependent urinary tract morphogenesis by Reginensi, Antoine, Hoshi, Masato, Boualia, Sami Kamel, Bouchard, Maxime, Jain, Sanjay, McNeill, Helen

“…Despite the high occurrence of congenital abnormalities of the lower urinary tract in humans, the molecular, cellular and morphological aspects of their…”
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Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development by Cappello, Silvia, Gray, Mary J, Badouel, Caroline, Lange, Simona, Einsiedler, Melanie, Srour, Myriam, Chitayat, David, Hamdan, Fadi F, Jenkins, Zandra A, Morgan, Tim, Preitner, Nadia, Uster, Tami, Thomas, Jackie, Shannon, Patrick, Morrison, Victoria, Di Donato, Nataliya, Van Maldergem, Lionel, Neuhann, Teresa, Newbury-Ecob, Ruth, Swinkells, Marielle, Terhal, Paulien, Wilson, Louise C, Zwijnenburg, Petra J G, Sutherland-Smith, Andrew J, Black, Michael A, Markie, David, Michaud, Jacques L, Simpson, Michael A, Mansour, Sahar, McNeill, Helen, Götz, Magdalena, Robertson, Stephen P

“…Magdalena Götz, Stephen Robertson and colleagues show that biallelic mutations in DCHS1 and FAT4 cause a multisystem disorder that includes periventricular…”
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Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth by Ragni, Chiara V., Diguet, Nicolas, Le Garrec, Jean-François, Novotova, Marta, Resende, Tatiana P., Pop, Sorin, Charon, Nicolas, Guillemot, Laurent, Kitasato, Lisa, Badouel, Caroline, Dufour, Alexandre, Olivo-Marin, Jean-Christophe, Trouvé, Alain, McNeill, Helen, Meilhac, Sigolène M

“…Although in flies the atypical cadherin Fat is an upstream regulator of Hippo signalling, the closest mammalian homologue, Fat4, has been shown to regulate…”
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Correction: The Rho Guanine Nucleotide Exchange Factor DRhoGEF2 Is a Genetic Modifier of the PI3K Pathway in Drosophila by Chang, Ying-Ju, Zhou, Lily, Binari, Richard, Manoukian, Armen, Mak, Tak, McNeill, Helen, Stambolic, Vuk

“…[This corrects the article DOI: 10.1371/journal.pone.0152259.]…”
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Planar polarity from flies to vertebrates by Fanto, Manolis, McNeill, Helen

“…Planar cell polarity (PCP) has been demonstrated in the epithelium of organisms from flies to humans. Recent research has revealed that the planar organization…”
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The atypical cadherin fat directly regulates mitochondrial function and metabolic state by Sing, Anson, Tsatskis, Yonit, Fabian, Lacramioara, Hester, Ian, Rosenfeld, Robyn, Serricchio, Mauro, Yau, Norman, Bietenhader, Maïlis, Shanbhag, Riya, Jurisicova, Andrea, Brill, Julie A, McQuibban, G Angus, McNeill, Helen

“…Fat (Ft) cadherins are enormous cell adhesion molecules that function at the cell surface to regulate the tumor-suppressive Hippo signaling pathway and planar…”
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Regulation of Neuronal Migration by Dchs1-Fat4 Planar Cell Polarity by Zakaria, Sana, Mao, Yaopan, Kuta, Anna, Ferreira de Sousa, Catia, Gaufo, Gary O., McNeill, Helen, Hindges, Robert, Guthrie, Sarah, Irvine, Kenneth D., Francis-West, Philippa H.

“…Planar cell polarity (PCP) describes the polarization of cell structures and behaviors within the plane of a tissue. PCP is essential for the generation of…”
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Unkempt is negatively regulated by mTOR and uncouples neuronal differentiation from growth control by Avet-Rochex, Amélie, Carvajal, Nancy, Christoforou, Christina P, Yeung, Kelvin, Maierbrugger, Katja T, Hobbs, Carl, Lalli, Giovanna, Cagin, Umut, Plachot, Cedric, McNeill, Helen, Bateman, Joseph M

“…Neuronal differentiation is exquisitely controlled both spatially and temporally during nervous system development. Defects in the spatiotemporal control of…”
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In Vivo Interaction Proteomics Reveal a Novel p38 Mitogen-Activated Protein Kinase/Rack1 Pathway Regulating Proteostasis in Drosophila Muscle by Belozerov, Vladimir E., Ratkovic, Srdjana, McNeill, Helen, Hilliker, Arthur J., McDermott, John C.

“…Classifications Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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