Search Results - "McNeil, Nicole M R"

Enhanced Glutathione Peroxidase Activity of Water-Soluble and Polyethylene Glycol-Supported Selenides, Related Spirodioxyselenuranes, and Pincer Selenuranes by McNeil, Nicole M. R, Press, David J, Mayder, Don M, Garnica, Pablo, Doyle, Lisa M, Back, Thomas G

“…Diaryl selenides containing o-hydroxymethylene substituents function as peroxide-destroying mimetics of the antioxidant selenoenzyme glutathione peroxidase…”
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NMR and Computational Studies of the Configurational Properties of Spirodioxyselenuranes. Are Dynamic Exchange Processes or Temperature-Dependent Chemical Shifts Involved? by Press, David J, McNeil, Nicole M. R, Rauk, Arvi, Back, Thomas G

“…Spirodioxyselenurane 4a and several substituted analogs revealed unexpected 1H NMR behavior. The diastereotopic methylene hydrogens of 4a appeared as an AB…”
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Structure–Activity Relationships of Potent, Targeted Covalent Inhibitors That Abolish Both the Transamidation and GTP Binding Activities of Human Tissue Transglutaminase by Akbar, Abdullah, McNeil, Nicole M. R, Albert, Marie R, Ta, Viviane, Adhikary, Gautam, Bourgeois, Karine, Eckert, Richard L, Keillor, Jeffrey W

“…Human tissue transglutaminase (hTG2) is a multifunctional enzyme. It is primarily known for its calcium-dependent transamidation activity that leads to…”
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Effects of Methoxy Substituents on the Glutathione Peroxidase-like Activity of Cyclic Seleninate Esters by Press, David J, McNeil, Nicole M. R, Hambrook, Miranda, Back, Thomas G

“…Cyclic seleninate esters function as mimetics of the antioxidant enzyme glutathione peroxidase and catalyze the reduction of hydrogen peroxide with a…”
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Fluxional Cyclic Seleninate Ester: NMR and Computational Studies, Glutathione Peroxidase-like Behavior, and Unexpected Rearrangement by McNeil, Nicole M. R, Matz, Marie C, Back, Thomas G

“…The oxidation of allyl selenide 12 with hydrogen peroxide produced the corresponding allyl selenurane 14, the cyclic seleninate ester 4, or the rearranged…”
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Oxidation of Disulfides to Thiolsulfinates with Hydrogen Peroxide and a Cyclic Seleninate Ester Catalyst by McNeil, Nicole M R, McDonnell, Ciara, Hambrook, Miranda, Back, Thomas G

“…Cyclic seleninate esters function as mimetics of the antioxidant selenoenzyme glutathione peroxidase. They catalyze the reduction of harmful peroxides with…”
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Novel irreversible peptidic inhibitors of transglutaminase 2 by Cundy, Nicholas J, Arciszewski, Jane, Gates, Eric W. J, Acton, Sydney L, Passley, Kyle D, Awoonor-Williams, Ernest, Boyd, Elizabeth K, Xu, Nancy, Pierson, Élise, Fernandez-Ansieta, Catalina, Albert, Marie R, McNeil, Nicole M. R, Adhikary, Gautam, Eckert, Richard L, Keillor, Jeffrey W

“…Transglutaminase 2 (TG2), also referred to as tissue transglutaminase, plays crucial roles in both protein crosslinking and cell signalling. It is capable of…”
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Structure-activity relationships of N-terminal variants of peptidomimetic tissue transglutaminase inhibitors by McNeil, Nicole M.R., Gates, Eric W.J., Firoozi, Neda, Cundy, Nicholas J., Leccese, Jessica, Eisinga, Sarah, Tyndall, Joel D.A., Adhikary, Gautam, Eckert, Richard L., Keillor, Jeffrey W.

“…Tissue transglutaminase (TG2) is a multifunctional protein that catalyses protein crosslinking in the extracellular matrix, and functions as an intracellular…”
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