Search Results - "McNally, Molly"
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Identification of pancreatic tumors in vivo with ligand-targeted, pH responsive mesoporous silica nanoparticles by multispectral optoacoustic tomography
Published in Journal of controlled release (10-06-2016)“…Despite significant efforts to translate nanotechnology for cancer application, lack of identification of biodistribution/accumulation of these nanovehicles in…”
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Active Targeting Significantly Outperforms Nanoparticle Size in Facilitating Tumor-Specific Uptake in Orthotopic Pancreatic Cancer
Published in ACS applied materials & interfaces (27-10-2021)“…Nanoparticles are widely studied as theranostic vehicles for cancer; however, clinical translation has been limited due to poor tumor specificity. Features…”
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Diabetes, Obesity, and Inflammation: Impact on Clinical and Radiographic Features of Breast Cancer
Published in International journal of molecular sciences (09-03-2021)“…Obesity, diabetes, and inflammation increase the risk of breast cancer, the most common malignancy in women. One of the mainstays of breast cancer treatment…”
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Mesoporous Silica Nanoparticles: Properties and Strategies for Enhancing Clinical Effect
Published in Pharmaceutics (17-04-2021)“…Due to the theragnostic potential of mesoporous silica nanoparticles (MSNs), these were extensively investigated as a novel approach to improve clinical…”
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Optoacoustic imaging identifies ovarian cancer using a microenvironment targeted theranostic wormhole mesoporous silica nanoparticle
Published in Biomaterials (01-11-2018)“…At the intersection of the newly emerging fields of optoacoustic imaging and theranostic nanomedicine, promising clinical progress can be made in dismal…”
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Tumor targeted mesoporous silica-coated gold nanorods facilitate detection of pancreatic tumors using Multispectral optoacoustic tomography
Published in Nano research (01-12-2015)“…Multispectral optoacoustic tomography (MSOT) is an emerging imaging technology that offers several advantages over traditional modalities, particularly in its…”
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Intraoperative Imaging in Hepatopancreatobiliary Surgery
Published in Cancers (20-07-2023)“…Hepatopancreatobiliary surgery belongs to one of the most complex fields of general surgery. An intricate and vital anatomy is accompanied by difficult…”
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The neutral red assay can be used to evaluate cell viability during autophagy or in an acidic microenvironment in vitro
Published in Biotechnic & histochemistry (19-05-2021)“…Harsh conditions within the tumor microenvironment, such as hypoxia and extracellular acidic pH (pH ), inactivate some chemotherapies, which results in limited…”
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Molecular Imaging of Inflammatory Disease
Published in Biomedicines (04-02-2021)“…Inflammatory diseases include a wide variety of highly prevalent conditions with high mortality rates in severe cases ranging from cardiovascular disease, to…”
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Abstract 2790: Evaluation of S100A9 targeted nanoparticles containing rapamycin to treat pancreatic adenocarcinoma
Published in Cancer research (Chicago, Ill.) (15-08-2020)“…Abstract Despite Pancreatic cancer being expected to contribute to only 3% of new cancer cases in both males and females in 2019, it is expected to cause an…”
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Abstract 1934: Development of spectrally distinct silica coated gold nanorods for detection of cancer using MSOT
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Traditional cancer imaging devices are limited in their ability to screen for multiple contrast agents simultaneously in real time. Multispectral…”
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Engagement in Early Intervention Services Among Mothers in Recovery From Opioid Use Disorders
Published in Pediatrics (Evanston) (01-02-2020)“…Opioid-exposed infants frequently qualify for early intervention (EI). However, many eligible families choose not to enroll in this voluntary service. This…”
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Abstract P1-01-04: Uptake of trastuzumab targeted mesoporous silica-coated chitosan capped gold nanorods in breast cancer cell lines and ex vivo patient samples
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Background: Approximately two-thirds of operative breast cancer cases are suitable for breast conserving surgery (BCS). In order for BCS to be…”
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Abstract P3-06-04: Tumor specific cargo release in ex vivo patient samples and murine models of triple negative breast cancer by a pH-targeted nanoparticle: V3-RUBY
Published in Cancer research (Chicago, Ill.) (15-02-2020)“…Abstract Background: Triple negative breast cancer (TNBC), unlike other breast cancer subtypes, lacks a specific targetable receptor. As such tumor specific…”
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Making Teaching Count: Optimization of Resident Conference Learning using Quality Improvement Methodology
Published in Pediatrics (Evanston) (01-08-2019)“…Background: Regularly scheduled didactics such as academic half days (AHDs) or noon conferences have become one of the primary modalities for structured…”
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Abstract 1952: Tumor microenvironment targeted Rosella nanoparticle for the detection of triple negative breast cancer by multispectral optoacoustic tomography
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Purpose: Recent advances in the nanotechnology and molecular imaging provides an excellent opportunity for development of delivery vehicles and…”
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Abstract 1937: pH-responsive tumor-targeted mesoporous silica nanoparticle for the identification of pancreatic cancer using optoacoustic tomography
Published in Cancer research (Chicago, Ill.) (01-07-2019)“…Abstract Purpose: Due to inadequate early detection and inability to operate at advanced stages, pancreatic ductal adenocarcinoma (PDAC) has remained one of…”
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Abstract 4664: Enzymatically-responsive tumor-targeted mesoporous silica nanoparticle for identification of pancreatic cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: Pancreatic cancer remains an unsolved health issue, with its rapid progression and resistance to modern therapy leading to poor prognoses for…”
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Abstract 4122: Acidic tumor microenvironment targeted wormhole-shaped mesoporous silica nanoparticles to detect ovarian cancer by multispectral optoacoustic tomography
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: The implementation of the innovative technologies remains the top priority for the development of potential modalities for the diagnosis and…”
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Abstract 3727: Dual acidic pH targeted mesoporous silica nanoparticles for noninvasive detection of triple negative breast cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: Current screening methods for triple negative breast cancer suggest the presence and size of tumor, but do not identify the tumor…”
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