Search Results - "McMullan, C."
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Genomes of the Mouse Collaborative Cross
Published in Genetics (Austin) (01-06-2017)“…The Collaborative Cross (CC) is a multiparent panel of recombinant inbred (RI) mouse strains derived from eight founder laboratory strains. RI panels are…”
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Myo19 Ensures Symmetric Partitioning of Mitochondria and Coupling of Mitochondrial Segregation to Cell Division
Published in Current biology (03-11-2014)“…During animal cell division, an actin-based ring cleaves the cell into two. Problems with this process can cause chromosome missegregation and defects in…”
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‘Well‐leg’ compartment syndrome associated with gynaecological surgery: a perioperative risk‐reduction protocol and checklist
Published in BJOG : an international journal of obstetrics and gynaecology (01-08-2021)“…‘Well‐leg’ compartment syndrome (WLCS) is an uncommon, but potentially devastating, complication associated with prolonged patient positioning for…”
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A realist process evaluation within the Facilitating Implementation of Research Evidence (FIRE) cluster randomised controlled international trial: an exemplar
Published in Implementation science : IS (16-11-2018)“…Facilitation is a promising implementation intervention, which requires theory-informed evaluation. This paper presents an exemplar of a multi-country realist…”
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Preparing for the future: challenges and opportunities for management and leadership skills
Published in British dental journal (01-01-2013)“…Key Points Opens up the debate on the role of management and leadership skills in the dental profession. Provides a leaders' perspective on their leadership…”
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Facilitating Implementation of Research Evidence (FIRE): an international cluster randomised controlled trial to evaluate two models of facilitation informed by the Promoting Action on Research Implementation in Health Services (PARIHS) framework
Published in Implementation science : IS (16-11-2018)“…Health care practice needs to be underpinned by high quality research evidence, so that the best possible care can be delivered. However, evidence from…”
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Transcriptional Signature of Histone Deacetylase Inhibition in Multiple Myeloma: Biological and Clinical Implications
Published in Proceedings of the National Academy of Sciences - PNAS (13-01-2004)“…Histone deacetylases (HDACs) affect cell growth at the transcriptional level by regulating the acetylation status of nucleosomal histones. HDAC inhibition…”
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Long‐term exercise in mice has sex‐dependent benefits on body composition and metabolism during aging
Published in Physiological reports (01-11-2016)“…Aging is associated with declining exercise and unhealthy changes in body composition. Exercise ameliorates certain adverse age‐related physiological changes…”
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A Bridge Over Turbulent Waters: Illustrating the Interaction Between Managerial Leaders and Facilitators When Implementing Research Evidence
Published in Worldviews on evidence-based nursing (01-02-2016)“…ABSTRACT Background Emerging evidence focuses on the importance of the role of leadership in successfully transferring research evidence into practice…”
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'I have the world's best job' - staff experience of the advantages of caring for older people
Published in Scandinavian journal of caring sciences (01-06-2016)“…Rationale Besides a growing demand for safe high‐quality care for older people, long‐term care (LTC) often struggles to recruit appropriately qualified nursing…”
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A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2
Published in PLoS genetics (01-02-2015)“…Significant departures from expected Mendelian inheritance ratios (transmission ratio distortion, TRD) are frequently observed in both experimental crosses and…”
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Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors
Published in Cancer cell (01-03-2004)“…Insulin-like growth factors and their receptor (IGF-1R) have been implicated in cancer pathophysiology. We demonstrate that IGF-1R is universally expressed in…”
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The surgical management of acute upper GI bleeding: Experiences from a district general hospital
Published in International journal of surgery (London, England) (01-11-2015)Get full text
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1657-P: Performance of Insulin Sensitivity Indices vs. the Hyperinsulinemic Euglycemic Clamp in Chronic Kidney Disease
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Background: Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD) and premature death. Insulin resistance (IR) is…”
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Race, Plasma Renin Activity, and Morning Blood Pressure Surge-Results From the Dietary Approaches to Stop Hypertension Trial
Published in American journal of hypertension (01-04-2014)“…BACKGROUND The association of preawake (difference between pre- and postwaking blood pressure (BP)) and sleep-through surge (difference between sleeping nadir…”
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Perinatal nutrition interacts with genetic background to alter behavior in a parent‐of‐origin‐dependent manner in adult Collaborative Cross mice
Published in Genes, brain and behavior (01-09-2018)“…Previous studies in animal models and humans have shown that exposure to nutritional deficiencies in the perinatal period increases the risk of psychiatric…”
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The Evolutionary Fates of a Large Segmental Duplication in Mouse
Published in Genetics (Austin) (01-09-2016)“…Gene duplication and loss are major sources of genetic polymorphism in populations, and are important forces shaping the evolution of genome content and…”
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A Large Mutational Study in Pachyonychia Congenita
Published in Journal of investigative dermatology (01-05-2011)“…Pachyonychia congenita (PC) is a rare autosomal dominant skin disorder characterized predominantly by nail dystrophy and painful palmoplantar keratoderma…”
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Increased expression of Candida albicans secretory proteinase, a putative virulence factor, in isolates from human immunodeficiency virus-positive patients
Published in Journal of Clinical Microbiology (01-10-1995)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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