Search Results - "McMillin, Shawna L"

Regulation of Skeletal Muscle Glucose Transport and Glucose Metabolism by Exercise Training by Evans, Parker L, McMillin, Shawna L, Weyrauch, Luke A, Witczak, Carol A

“…Aerobic exercise training and resistance exercise training are both well-known for their ability to improve human health; especially in individuals with type 2…”
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Insulin Resistance Does Not Impair Mechanical Overload-Stimulated Glucose Uptake, but Does Alter the Metabolic Fate of Glucose in Mouse Muscle by Weyrauch, Luke A, McMillin, Shawna L, Witczak, Carol A

“…Skeletal muscle glucose uptake and glucose metabolism are impaired in insulin resistance. Mechanical overload stimulates glucose uptake into insulin-resistant…”
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Insulin Resistance Is Not Sustained Following Denervation in Glycolytic Skeletal Muscle by McMillin, Shawna L, Stanley, Erin C, Weyrauch, Luke A, Brault, Jeffrey J, Kahn, Barbara B, Witczak, Carol A

“…Denervation rapidly induces insulin resistance (i.e., impairments in insulin-stimulated glucose uptake and signaling proteins) in skeletal muscle…”
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Contribution of Insulin and Akt1 Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure by Symons, J David, McMillin, Shawna L, Riehle, Christian, Tanner, Jason, Palionyte, Milda, Hillas, Elaine, Jones, Deborah, Cooksey, Robert C, Birnbaum, Morris J, McClain, Donald A, Zhang, Quan-Jiang, Gale, Derrick, Wilson, Lloyd J, Abel, E Dale

“…Impaired insulin signaling via phosphatidylinositol 3-kinase/Akt to endothelial nitric oxide synthase (eNOS) in the vasculature has been postulated to lead to…”
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Endothelial nitric oxide synthase phosphorylation in treadmill-running mice: role of vascular signalling kinases by Zhang, Quan‐Jiang, McMillin, Shawna L., Tanner, Jason M., Palionyte, Milda, Abel, E. Dale, Symons, J. David

“…The intracellular signalling kinases Akt/protein kinase B (Akt), protein kinase A (PKA) and adenosine monophosphate-activated protein kinase (AMPK) are…”
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Muscle-Specific Ablation of Glucose Transporter 1 (GLUT1) Does Not Impair Basal or Overload-Stimulated Skeletal Muscle Glucose Uptake by McMillin, Shawna L, Evans, Parker L, Taylor, William M, Weyrauch, Luke A, Sermersheim, Tyler J, Welc, Steven S, Heitmeier, Monique R, Hresko, Richard C, Hruz, Paul W, Koumanov, Francoise, Holman, Geoffrey D, Abel, E Dale, Witczak, Carol A

“…Glucose transporter 1 (GLUT1) is believed to solely mediate basal (insulin-independent) glucose uptake in skeletal muscle; yet recent work has demonstrated…”
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Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation by Iñigo, Melissa R., Amorese, Adam J., Tarpey, Michael D., Balestrieri, Nicholas P., Jones, Keith G., Patteson, Daniel J., Jackson, Kathryn C., Torres, Maria.J., Lin, Chien-Te, Smith, Cody D., Heden, Timothy D., McMillin, Shawna L., Weyrauch, Luke A., Stanley, Erin C., Schmidt, Cameron A., Kilburg-Basnyat, Brita B., Reece, Sky W., Psaltis, Christine E., Leinwand, Leslie A., Funai, Katsuhiko, McClung, Joseph M., Gowdy, Kymberly M., Witczak, Carol A., Lowe, Dawn A., Neufer, P. Darrell, Spangenburg, Espen E.

“…Estrogen receptor-α (ERα) is a nuclear receptor family member thought to substantially contribute to the metabolic regulation of skeletal muscle. However,…”
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Skeletal muscle wasting: the estrogen side of sexual dimorphism by McMillin, Shawna L, Minchew, Everett C, Lowe, Dawn A, Spangenburg, Espen E

“…The importance of defining sex differences across various biological and physiological mechanisms is more pervasive now than it has been over the past 15-20…”
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Ablation of skeletal muscle estrogen receptor alpha impairs contractility in male mice by Sullivan, Brian P, Collins, Brittany C, McMillin, Shawna L, Toussaint, Elise, Stein, Clara Z, Spangenburg, Espen E, Lowe, Dawn A

“…Estradiol and estrogen receptor α (ERα) have been shown to be important for the maintenance of skeletal muscle strength in females, however little is known…”
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GLUT4 Is Not Necessary for Overload-Induced Glucose Uptake or Hypertrophic Growth in Mouse Skeletal Muscle by McMillin, Shawna L, Schmidt, Denise L, Kahn, Barbara B, Witczak, Carol A

“…GLUT4 is necessary for acute insulin- and contraction-induced skeletal muscle glucose uptake, but its role in chronic muscle loading (overload)-induced glucose…”
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Estradiol deficiency reduces the satellite cell pool by impairing cell cycle progression by Larson, Alexie A, Shams, Ahmed S, McMillin, Shawna L, Sullivan, Brian P, Vue, Cha, Roloff, Zachery A, Batchelor, Eric, Kyba, Michael, Lowe, Dawn A

“…The size of the satellite cell pool is reduced in estradiol (E )-deficient female mice and humans. Here, we use a combination of in vivo and in vitro…”
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Genetically increasing flux through β-oxidation in skeletal muscle increases mitochondrial reductive stress and glucose intolerance by Smith, Cody D, Lin, Chien-Te, McMillin, Shawna L, Weyrauch, Luke A, Schmidt, Cameron A, Smith, Cheryl A, Kurland, Irwin J, Witczak, Carol A, Neufer, P Darrell

“…Elevated mitochondrial hydrogen peroxide (H O ) emission and an oxidative shift in cytosolic redox environment have been linked to high-fat-diet-induced…”
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Hypoxia Resistance Is an Inherent Phenotype of the Mouse Flexor Digitorum Brevis Skeletal Muscle by Amorese, Adam J, Minchew, Everett C, Tarpey, Michael D, Readyoff, Andrew T, Williamson, Nicholas C, Schmidt, Cameron A, McMillin, Shawna L, Goldberg, Emma J, Terwilliger, Zoe S, Spangenburg, Quincy A, Witczak, Carol A, Brault, Jeffrey J, Abel, E Dale, McClung, Joseph M, Fisher-Wellman, Kelsey H, Spangenburg, Espen E

“…Abstract The various functions of skeletal muscle (movement, respiration, thermogenesis, etc.) require the presence of oxygen (O2). Inadequate O2…”
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Influence of estradiol deficiency on the acute inflammatory response following a traumatic skeletal muscle injury by McMillin, Shawna L, Noel, Richard, O’Farrell, Laura, Warren, Gordon, Lowe, Dawn

“…Abstract Estradiol (E2) influences the inflammatory response. Research has shown that skeletal muscle chemokine mRNA expression and neutrophil infiltration…”
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Contribution of Insulin and Aktl Signaling to Endothelial Nitric Oxide Synthase in the Regulation of Endothelial Function and Blood Pressure by SYMONS, J. David, MCMILLIN, Shawna L, ZHANG, Quan-Jiang, GALE, Derrick, WILSON, Lloyd J, DALE ABEL, E, RIEHLE, Christian, TANNER, Jason, PALIONYTE, Milda, HILLAS, Elaine, JONES, Deborah, COOKSEY, Robert C, BIRNBAUM, Morris J, MCCLAIN, Donald A

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