Search Results - "McMillan, A"

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets by Witkiewicz, Agnieszka K., McMillan, Elizabeth A., Balaji, Uthra, Baek, GuemHee, Lin, Wan-Chi, Mansour, John, Mollaee, Mehri, Wagner, Kay-Uwe, Koduru, Prasad, Yopp, Adam, Choti, Michael A., Yeo, Charles J., McCue, Peter, White, Michael A., Knudsen, Erik S.

“…Pancreatic ductal adenocarcinoma (PDA) has a dismal prognosis and insights into both disease etiology and targeted intervention are needed. A total of 109…”
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LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer by Tavazoie, Masoud F., Pollack, Ilana, Tanqueco, Raissa, Ostendorf, Benjamin N., Reis, Bernardo S., Gonsalves, Foster C., Kurth, Isabel, Andreu-Agullo, Celia, Derbyshire, Mark L., Posada, Jessica, Takeda, Shugaku, Tafreshian, Kimia N., Rowinsky, Eric, Szarek, Michael, Waltzman, Roger J., Mcmillan, Elizabeth A., Zhao, Connie, Mita, Monica, Mita, Alain, Chmielowski, Bartosz, Postow, Michael A., Ribas, Antoni, Mucida, Daniel, Tavazoie, Sohail F.

“…Therapeutic harnessing of adaptive immunity via checkpoint inhibition has transformed the treatment of many cancers. Despite unprecedented long-term responses,…”
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Transferable Plasmids of Salmonella enterica Associated With Antibiotic Resistance Genes by McMillan, Elizabeth A., Jackson, Charlene R., Frye, Jonathan G.

“…Salmonella enterica is a common foodborne illness in the United States and globally. An increasing number of Salmonella infections are resistant to…”
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Experimental verification of multipartite entanglement in quantum networks by McCutcheon, W., Pappa, A., Bell, B. A., McMillan, A., Chailloux, A., Lawson, T., Mafu, M., Markham, D., Diamanti, E., Kerenidis, I., Rarity, J. G., Tame, M. S.

“…Multipartite entangled states are a fundamental resource for a wide range of quantum information processing tasks. In particular, in quantum networks, it is…”
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Patterns of NPP, GPP, respiration, and NEP during boreal forest succession by GOULDEN, M.L, MCMILLAN, A.M.S, WINSTON, G.C, ROCHA, A.V, MANIES, K.L, HARDEN, J.W, BOND-LAMBERTY, B.P

“…We combined year-round eddy covariance with biometry and biomass harvests along a chronosequence of boreal forest stands that were 1, 6, 15, 23, 40, ∼74, and…”
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Metabolic Diversity in Human Non-Small Cell Lung Cancer Cells by Chen, Pei-Hsuan, Cai, Ling, Huffman, Kenneth, Yang, Chendong, Kim, Jiyeon, Faubert, Brandon, Boroughs, Lindsey, Ko, Bookyung, Sudderth, Jessica, McMillan, Elizabeth A., Girard, Luc, Chen, Dong, Peyton, Michael, Shields, Misty D., Yao, Bo, Shames, David S., Kim, Hyun Seok, Timmons, Brenda, Sekine, Ikuo, Britt, Rebecca, Weber, Stephanie, Byers, Lauren A., Heymach, John V., Chen, Jing, White, Michael A., Minna, John D., Xiao, Guanghua, DeBerardinis, Ralph J.

“…Intermediary metabolism in cancer cells is regulated by diverse cell-autonomous processes, including signal transduction and gene expression patterns, arising…”
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Twin-beam sub-shot-noise raster-scanning microscope by Sabines-Chesterking, J., McMillan, A. R., Moreau, P. A., Joshi, S. K., Knauer, S., Johnston, E., Rarity, J. G., Matthews, J. C. F.

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A Field and Modeling Study of Fractured Rock Permeability Reduction Using Microbially Induced Calcite Precipitation by Cuthbert, Mark O, McMillan, Lindsay A, Handley-Sidhu, Stephanie, Riley, Michael. S, Tobler, Dominique J, Phoenix, Vernon. R

“…Microbially induced calcite precipitation (MICP) offers an attractive alternative to traditional grouting technologies for creating barriers to groundwater…”
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Systemic Delivery of CRISPR/Cas9 Targeting HPV Oncogenes Is Effective at Eliminating Established Tumors by Jubair, Luqman, Fallaha, Sora, McMillan, Nigel A.J.

“…The recent advancements in CRISPR/Cas9 engineering have resulted in the development of more targeted and potentially safer gene therapies. The challenge in the…”
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Molecular determinants of nephron vascular specialization in the kidney by Barry, David M., McMillan, Elizabeth A., Kunar, Balvir, Lis, Raphael, Zhang, Tuo, Lu, Tyler, Daniel, Edward, Yokoyama, Masataka, Gomez-Salinero, Jesus M., Sureshbabu, Angara, Cleaver, Ondine, Di Lorenzo, Annarita, Choi, Mary E., Xiang, Jenny, Redmond, David, Rabbany, Sina Y., Muthukumar, Thangamani, Rafii, Shahin

“…Although kidney parenchymal tissue can be generated in vitro, reconstructing the complex vasculature of the kidney remains a daunting task. The molecular…”
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KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II by McNamara, Ryan P., Reeder, Jonathan E., McMillan, Elizabeth A., Bacon, Curtis W., McCann, Jennifer L., D’Orso, Iván

“…The transition from transcription initiation to elongation at promoters of primary response genes (PRGs) in metazoan cells is controlled by inducible…”
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CRISPR/Cas9-loaded stealth liposomes effectively cleared established HPV16-driven tumours in syngeneic mice by Jubair, Luqman, Lam, Alfred K, Fallaha, Sora, McMillan, Nigel A J

“…Gene-editing has raised the possibility of being able to treat or cure cancers, but key challenges remain, including efficient delivery, in vivo efficacy, and…”
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Small-molecule TFEB pathway agonists that ameliorate metabolic syndrome in mice and extend C. elegans lifespan by Wang, Chensu, Niederstrasser, Hanspeter, Douglas, Peter M., Lin, Rueyling, Jaramillo, Juan, Li, Yang, Oswald, Nathaniel W., Zhou, Anwu, McMillan, Elizabeth A., Mendiratta, Saurabh, Wang, Zhaohui, Zhao, Tian, Lin, Zhiqaing, Luo, Min, Huang, Gang, Brekken, Rolf A., Posner, Bruce A., MacMillan, John B., Gao, Jinming, White, Michael A.

“…Drugs that mirror the cellular effects of starvation mimics are considered promising therapeutics for common metabolic disorders, such as obesity, liver…”
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Prevalence and characterization of Escherichia coli isolated from the Upper Oconee Watershed in Northeast Georgia by Cho, Sohyun, Hiott, Lari M, Barrett, John B, McMillan, Elizabeth A, House, Sandra L, Humayoun, Shaheen B, Adams, Eric S, Jackson, Charlene R, Frye, Jonathan G

“…Surface waters are important sources of water for drinking, industrial, agricultural, and recreational uses; hence, contamination of water by fecal,…”
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Review: Examining the Natural Role of Amphibian Antimicrobial Peptide Magainin by McMillan, Katelyn A M, Coombs, Melanie R Power

“…Host defense peptides (HDPs) are a group of antimicrobial peptides (AMPs) that are crucial components of the innate immune system of many different organisms…”
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Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial by Patel, B, Kirkwood, A A, Dey, A, Marks, D I, McMillan, A K, Menne, T F, Micklewright, L, Patrick, P, Purnell, S, Rowntree, C J, Smith, P, Fielding, A K

“…Safety and efficacy data on pegylated asparaginase (PEG-ASP) in adult acute lymphoblastic leukaemia (ALL) induction regimens are limited. The UK National…”
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Prevalence and Subtype Characterization of Campylobacter in Ceca of Commercial Broiler Chickens at Processing – A 452 Flock, Seven-year Survey by Berrang, Mark E., McMillan, Elizabeth A., Knapp, Steven W., Meinersmann, Richard J.

“…Human Campylobacter infections have been associated with chicken and other poultry meat products. Environmental conditions such as temperature and season can…”
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TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer by Cooper, Jonathan M, Ou, Yi-Hung, McMillan, Elizabeth A, Vaden, Rachel M, Zaman, Aubhishek, Bodemann, Brian O, Makkar, Gurbani, Posner, Bruce A, White, Michael A

“…Emerging observations link dysregulation of TANK-binding kinase 1 (TBK1) to developmental disorders, inflammatory disease, and cancer. Biochemical mechanisms…”
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Exudate From Retail Chicken Liver Packaging Allows for Survival of Naturally Occurring Campylobacter, Coliforms, and Aerobic Microorganisms Under Drying Conditions by McMillan, Elizabeth A., Berrang, Mark E., Adams, Eric S., Meinersmann, Richard J.

“…•Campylobacter was detected in fresh retail chicken liver exudate.•Campylobacter from exudate survived up to 24 h under drying conditions.•Campylobacter…”
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Development of novel lipidic particles for siRNA delivery that are highly effective after 12 months storage by Clarke, Daniel, Idris, Adi, McMillan, Nigel A J

“…Liposomes are versatile and well-proven as a means to deliver nucleic acids into cells. Most of the formulation procedures used are labour intensive and result…”
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