Search Results - "McMichael, Temet"
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E3 Ubiquitin Ligase NEDD4 Promotes Influenza Virus Infection by Decreasing Levels of the Antiviral Protein IFITM3
Published in PLoS pathogens (01-08-2015)“…Interferon (IFN)-induced transmembrane protein 3 (IFITM3) is a cell-intrinsic factor that limits influenza virus infections. We previously showed that IFITM3…”
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Occupational exposures and mitigation strategies among homeless shelter workers at risk of COVID-19
Published in PloS one (01-11-2021)“…Objective To describe the work environment and COVID-19 mitigation measures for homeless shelter workers and assess occupational risk factors for COVID-19…”
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Epidemiology of Covid-19 in a Long-Term Care Facility in King County, Washington
Published in The New England journal of medicine (21-05-2020)“…On February 28, 2020, public health officials in the Seattle area were informed of a Covid-19 infection at a long-term care facility. An investigation…”
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From APOBEC to ZAP: Diverse mechanisms used by cellular restriction factors to inhibit virus infections
Published in Biochimica et biophysica acta. Molecular cell research (01-03-2019)“…Antiviral restriction factors are cellular proteins that inhibit the entry, replication, or spread of viruses. These proteins are critical components of the…”
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Phosphorylation of the Antiviral Protein Interferon-inducible Transmembrane Protein 3 (IFITM3) Dually Regulates Its Endocytosis and Ubiquitination
Published in The Journal of biological chemistry (25-04-2014)“…Interferon-inducible transmembrane protein 3 (IFITM3) is essential for innate defense against influenza virus in mice and humans. IFITM3 localizes to…”
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Interferon-induced transmembrane proteins inhibit cell fusion mediated by trophoblast syncytins
Published in The Journal of biological chemistry (27-12-2019)“…Type I interferon (IFN) induced by virus infections during pregnancy can cause placental damage, but the mechanisms and identities of IFN-stimulated genes that…”
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IFITM3 requires an amphipathic helix for antiviral activity
Published in EMBO reports (01-10-2017)“…Interferon‐induced transmembrane protein 3 (IFITM3) is a cellular factor that blocks virus fusion with cell membranes. IFITM3 has been suggested to alter…”
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Human Genetic Determinants of Viral Diseases
Published in Annual review of genetics (27-11-2017)“…Much progress has been made in the identification of specific human gene variants that contribute to enhanced susceptibility or resistance to viral diseases…”
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The palmitoyltransferase ZDHHC20 enhances interferon-induced transmembrane protein 3 (IFITM3) palmitoylation and antiviral activity
Published in The Journal of biological chemistry (29-12-2017)“…Interferon-induced transmembrane protein 3 (IFITM3) is a cellular endosome- and lysosome-localized protein that restricts numerous virus infections. IFITM3 is…”
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10
IFITM3 protects the heart during influenza virus infection
Published in Proceedings of the National Academy of Sciences - PNAS (10-09-2019)“…Influenza virus can disseminate from the lungs to the heart in severe infections and can induce cardiac pathology, but this has been difficult to study due to…”
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MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
Published in Nature communications (17-07-2020)“…TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed…”
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Regulation of the trafficking and antiviral activity of IFITM3 by post-translational modifications
Published in Future microbiology (01-10-2014)“…IFITM3 restricts cellular infection by multiple important viral pathogens, and is particularly critical for the innate immune response against influenza virus…”
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Use of standard, contact, and droplet precautions with eye protection for the prevention of severe acute respiratory coronavirus virus 2 (SARS-CoV-2) transmission among home healthcare personnel in hospice and home healthcare settings—King and Snohomish counties, Washington, February–October 2020
Published in Infection control and hospital epidemiology (01-03-2023)“…Among EvergreenHealth Home Care Service professionals, no coronavirus disease 2019 (COVID-19) cases were reported when they were instructed to use standard,…”
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IFITM3 Restricts Human Metapneumovirus Infection
Published in The Journal of infectious diseases (05-10-2018)“…Human metapneumovirus (hMPV) utilizes a bifurcated cellular entry strategy, fusing either with the plasma membrane or, after endocytosis, with the endosome…”
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Palmitoylation on Conserved and Nonconserved Cysteines of Murine IFITM1 Regulates Its Stability and Anti-Influenza A Virus Activity
Published in Journal of Virology (01-09-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Shigellosis outbreak among persons experiencing homelessness—San Diego County, California, October–December 2021
Published in Epidemiology and infection (01-01-2024)“…During October 2021, the County of San Diego Health and Human Services Agency identified five cases of shigellosis among persons experiencing homelessness…”
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Shelter Characteristics, Infection Prevention Practices, and Universal Testing for SARS-CoV-2 at Homeless Shelters in 7 US Urban Areas
Published in American journal of public health (1971) (01-05-2021)“…To examine shelter characteristics and infection prevention practices in relation to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection…”
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A balancing act between IFITM3 and IRF3
Published in Cellular & molecular immunology (01-10-2018)Get full text
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Assessment of SARS-CoV-2 Infection Prevalence in Homeless Shelters - Four U.S. Cities, March 27-April 15, 2020
Published in MMWR. Morbidity and mortality weekly report (01-05-2020)“…In the United States, approximately 1.4 million persons access emergency shelter or transitional housing each year (1). These settings can pose risks for…”
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COVID-19 Outbreak Among Three Affiliated Homeless Service Sites - King County, Washington, 2020
Published in MMWR. Morbidity and mortality weekly report (01-05-2020)“…On March 30, 2020, Public Health - Seattle and King County (PHSKC) was notified of a confirmed case of coronavirus disease 2019 (COVID-19) in a resident of a…”
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